DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3097 and AGBL1

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_001373023.1	Gene:	AGBL1 / 123624	HGNCID:	26504	Length:	1121	Species:	Homo sapiens

Alignment Length:	310	Identity:	61/310 - (19%)
Similarity:	104/310 - (33%)	Gaps:	105/310 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 YHDLETIYSFMR--EIRTKFPNIVRLY----TIGQTAEGRDLKVLRISENPRENKKVWID----- 201
            ||...|..:.|.  :|..|..|:..:|    .:.||..|....::.|:..|..|....::
Human   730 YHYPYTYTALMTHLDILEKSVNLKEVYFRQDVLCQTLGGNPCPLVTITAMPESNSDEHLEQFRHR 794

  Fly   202 ------GGIHARE----WISPATVTFILYQLMSDWENQP-AHI--RGLTWYIMPVMNPDGYEYSR 253
                  ..:|..|    |:...|:.|::       .:.| |.:  ....:.|:|::||||.
Human   795 PYQVITARVHPGESNASWVMKGTLEFLV-------SSDPVARLLRENFIFKIIPMLNPDGV---- 848

  Fly   254 TTNRLWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAK 318
                     .:.:.|...||.||||.    |....:...|.....:|..
Human   849 ---------INGNHRCSLSGEDLNRQ----WLSPSAHLQPTIYHAKGLL---------------- 884

  Fly   319 RKYNLES-------YLTFHSYGQ---MIVYPWAYK------AVKVKDASVLQRVSSLAAERILQK 367
              |:|.|       :..||.:.|   :.:|..:.|      |..|..:::|:.|:.....:||.|
Human   885 --YHLSSIGRSPVVFCDFHGHSQKKNVFLYGCSIKETLWQAACTVGTSTILEEVNYRTLPKILDK 947

  Fly   368 TGTSY------------RAAVTHEVLGIAGGGSDDWSRAALGVKYVYTIE 405
            ...::            ||:....|:         |..  :||...||:|
Human   948 LAPAFTMSSCSFLVEKSRASTARVVV---------WRE--MGVSRSYTME 986

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	61/310 (20%)
AGBL1	NP_001373023.1	Pepdidase_M14_N	596..730	CDD:407865	61/310 (20%)
AGBL1	NP_001373023.1	M14_Nna1	754..1019	CDD:349477	54/286 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900