DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4078 and AT1G79890

DIOPT Version :9

Sequence 1:	NP_001259262.1	Gene:	CG4078 / 31497	FlyBaseID:	FBgn0029798	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_178107.1	Gene:	AT1G79890 / 844328	AraportID:	AT1G79890	Length:	882	Species:	Arabidopsis thaliana

Alignment Length:	928	Identity:	240/928 - (25%)
Similarity:	393/928 - (42%)	Gaps:	257/928 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FPFEPYPVQRAYMEKVIHCLRDGTNGVLESPTGTGKTLSLLCSSLAWIRTRQS------------ 65
            ||::||.:|..:|..:...|..|...:|||||||||:||::||:|.|:..|:.
plant    10 FPYKPYSIQIDFMNALYQFLDKGGVSMLESPTGTGKSLSIICSALQWLTDRKEKRNSGLTEESHK 74

  Fly    66 ----------------------------------------EHQKQM-VKMEKAD----------- 78
                                                    :|.|:: .:.||||
plant    75 VDGNDDEDEPDWMRNFTLNEADGANGDKSIKNTKSPFSLRKHAKEVFTEGEKADELNDQEFLLDE 139

  Fly    79 FSGLGGGAPGGDLSELAKTMG---------------RANNWGVPKVIYASRTHSQLTQAMRELKR 128
            :......:|||..|:.....|               ..:..|..||.:.|||||||:|.::||::
plant   140 YESQDESSPGGGNSKRKPARGFDSSSSEDEEDENDCSDDEQGGFKVFFCSRTHSQLSQFVKELRK 204

  Fly   129 TAYA-NMRSVVLGSRDQLCIHPEVMREQGN-------------------SNKTNM---------- 163
            |.:| .::.|.||||..|||:.:|:: .||                   |.|.|:
plant   205 TVFAKKLKVVCLGSRKNLCINEDVLK-LGNVTRINERCLDLQKKKISQVSKKKNLGANVRIVRTK 268

  Fly   164 --CK---LRVHS-----KTCSFQMRVESRKDHPDLRGPTIMDIEDLVKVGQRLKICPYFASRELV 218
              |:   ||.|.     |..|||...              |||||||::|:.::.|||:.||.:.
plant   269 ASCRCPMLRKHKLQREFKAESFQQEA--------------MDIEDLVQLGREMRTCPYYGSRRMA 319

  Fly   219 PQADITFMPYNYLLDPKARKANKIELGNTIVILDEAHNIEKICEESASVQIKSSDVAMAI---ED 280
            |.||:..:||..||...:|::..:.|.|::||:|||||:       |...:...|..:.:   ||
plant   320 PAADLVILPYQSLLSKSSRESLGLSLKNSVVIIDEAHNL-------ADTLLSMHDAKLTVSQLED 377

  Fly   281 VTHIMQVFASGESQDMAGDEPKDFTLDDLTLLKEMLLELEKAIDAIVVDNAVDGTTFPA------ 339
            :...::.:. |..|::.|...:.:....|.|.:..|..|....:...|:..:| |..|:
plant   378 IHCSIESYL-GRFQNLLGAGNRRYIQIMLILTRAFLKPLASDRNLSSVNVGLD-TENPSKSKPCG 440

  Fly   340 --SM-MYELLGKANFTYGNVATIVSLLDK----------------LVQYLLVASQQMSIRKGGTF 385
              || :|:.|...|....|:..:::.:.:                ::|...||.::||  |..:|
plant   441 ACSMAIYDFLFSLNIDNINLVKLLAYIKESNIIHKVSGYGERVAAMLQKDPVAHEEMS--KLTSF 503

  Fly   386 TLLSDLLTIVFANKED---VMSKVYASFKVHVLVEESKQGHGKQQGAKQQGGWLGKGTIAAATGL 447
            ...||:|..:..|..|   ::|:..:|                  .:.|.||::   .....||.
plant   504 RAFSDMLVALTNNNGDGRIIISRTSSS------------------TSGQHGGYI---KYVMLTGA 547

  Fly   448 SKVAKIINFWCFNPGFGMEQLLNTQVRSVILTSGTLAPLKP----LIAELAIPVAQHLENPHIVD 508
            ...:::::                :..:|||..|||.|::.    |...|.....|.....|||.
plant   548 KLFSEVVD----------------EAHAVILAGGTLQPIEETRERLFPWLPSNQLQFFSCSHIVP 596

  Fly   509 QSQVYVKIIGTGPDRQQLISNYANRDNPKYISSLGQTILNVARIVPDGLLVFFPSYPMLNKCVDA 573
            ...:....:..||..|....::::|.:...|..||..:.|:..:||:|::|||.|:....:...|
plant   597 PESIMPIAVSHGPSGQSFDFSHSSRSSIGMIQELGLLMSNLVAVVPEGIIVFFSSFEYETQVHTA 661

  Fly   574 WQASGLWADISCKKPIFLEPRSKDQFTSTMEEFYQAIRDSKGAVFMAVCRGKVSEGLDFADRNGR 638
            |..||:...|..||.:|.|||...:..:.:.::.:||...:||:.:||..||||||::|:|...|
plant   662 WSNSGILRRIVKKKRVFREPRKNTEVEAVLRDYKEAIESERGAIMLAVVGGKVSEGINFSDSMCR 726

  Fly   639 AVIITGLPFPPLKDPKVILKRRYLEANRTRENQLLS--------------------------GQE 677
            .|::.|||:|...|.:::.:.:::|.....::...|                          |:|
plant   727 CVVMVGLPYPSPSDIELLERIKHIEGRADSDSIKPSVTLVDDSYYSGDVQAGFGVLKSCKRRGKE 791

  Fly   678 WYNLDATRAVNQAIGRVIRHRNDYGAILLCDSRF-KDASQ-------VQQLSKWIRGHLGDRPQC 734
            :|.....:||||:|||.|||..||.:|||.|:|: .|.|:       ..:|.|||:    ||...
plant   792 YYENLCMKAVNQSIGRAIRHEKDYASILLVDARYSNDPSKRTSHSHPSNKLPKWIK----DRLIY 852

  Fly   735 SP--FGPIVRELRQFFKN 750
            |.  :|.:.|.|.||||:
plant   853 STKGYGDVHRLLHQFFKH 870

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4078	NP_001259262.1	rad3	10..742	CDD:273169	234/918 (25%)
		DEAD_2	111..274	CDD:284209	65/202 (32%)
		Helicase_C_2	546..725	CDD:290046	67/212 (32%)
		HN_RTEL1	896..985	CDD:259826
AT1G79890	NP_178107.1	DinG	1..846	CDD:224120	228/898 (25%)
		DEAD_2	187..375	CDD:284209	66/209 (32%)
		Helicase_C_2	636..849	CDD:290046	68/216 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186062at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820