DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4078 and UVH6

DIOPT Version :9

Sequence 1:	NP_001259262.1	Gene:	CG4078 / 31497	FlyBaseID:	FBgn0029798	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_171818.1	Gene:	UVH6 / 839557	AraportID:	AT1G03190	Length:	758	Species:	Arabidopsis thaliana

Alignment Length:	838	Identity:	193/838 - (23%)
Similarity:	351/838 - (41%)	Gaps:	166/838 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IAGIPVHFPFEP-YPVQRAYMEKVIHCLRDGTNGVLESPTGTGKTLSLLCSSLAWIRTRQSEHQK 69
            |..:.|:||::. ||.|..||.::...|....:.:||.|||||||::||....::..:|
plant     5 IEDVTVYFPYDNIYPEQYEYMVELKRALDAKGHCLLEMPTGTGKTIALLSLITSYRLSR------ 63

  Fly    70 QMVKMEKADFSGLGGGAPGGDLSELAKTMGRANNWGVPKVIYASRTHSQLTQAMRELKRT----- 129
                             |...:                |::|.:||..::.:.:.|||..
plant    64 -----------------PDSPI----------------KLVYCTRTVHEMEKTLGELKLLHDYQV 95

  Fly   130 ----AYANMRSVVLGSRDQLCIHPEVMREQGNSNKTNMCKLRVHS------------KTCSFQMR 178
                ..|.:.::.|.||..||::.:|:..:...:....|:.|..|            :.|.|...
plant    96 RHLGTQAKILALGLSSRKNLCVNTKVLAAENRDSVDAACRKRTASWVRALSTENPNVELCDFFEN 160

  Fly   179 VESRKDHPDLRGPTIMDIEDLVKVGQRLKICPYFASRELVPQADITFMPYNYLLDPKARKANKIE 243
            .|...::. |..|.:..:|||...|:....||||.:|.::..|::....|.||||||.......|
plant   161 YEKAAENA-LLPPGVYTLEDLRAFGKNRGWCPYFLARHMIQFANVIVYSYQYLLDPKVAGFISKE 224

  Fly   244 L-GNTIVILDEAHNIEKICEESASVQIKSSDVAMAIEDVTHIMQVFASGESQDMAGDEPKDFTLD 307
            | ..::|:.||||||:.:|.|:.||.::...:..|..::..|.|.....::.| ||
plant   225 LQKESVVVFDEAHNIDNVCIEALSVSVRRVTLEGANRNLNKIRQEIDRFKATD-AG--------- 279

  Fly   308 DLTLLKEMLLELEKAIDAIVVDNAVDG----TTFPASMMYELLGKANFTYGNVAT---IVSLLDK 365
                  .:..|..:.::.:.:...:.|    ...|| :.:::|.:|  ..||:..   .|.:|.:
plant   280 ------RLRAEYNRLVEGLALRGDLSGGDQWLANPA-LPHDILKEA--VPGNIRRAEHFVHVLRR 335

  Fly   366 LVQYLLVASQQMSIRKGGTFTLLSDL----------------------LTIVFANKEDVMS-KVY 407
            |:|||.|.....::.|....:.:|.|                      ||:...:.::.:. :..
plant   336 LLQYLGVRLDTENVEKESPVSFVSSLNSQAGIEQKTLKFCYDRLQSLMLTLEITDTDEFLPIQTV 400

  Fly   408 ASFKVHVLVEESKQGHGKQQGAKQQGGWLGKGTIAAATGLSKVAK------------IINFWCFN 460
            ..|...|                        ||.  |.|.|.:.:            |:...|.:
plant   401 CDFATLV------------------------GTY--ARGFSIIIEPYDERMPHIPDPILQLSCHD 439

  Fly   461 PGFGMEQLLNTQVRSVILTSGTLAP--LKPLIAELAIPVAQHLENPHIVDQSQVYVKIIGTGPDR 523
            ....::.:.: :.:||::|||||:|  |.|.:......|::..:..  :.:..:...::..|.|:
plant   440 ASLAIKPVFD-RFQSVVITSGTLSPIDLYPRLLNFTPVVSRSFKMS--MTRDCICPMVLTRGSDQ 501

  Fly   524 QQLISNYANRDNPKYISSLGQTILNVARIVPDGLLVFFPSYPMLNKCVDAWQASGLWADISCKKP 588
            ..:.:.:..|.:|..:.:.|:.::.:..|||||::.||.||..::..:..|..:|:..:|..:|.
plant   502 LPVSTKFDMRSDPGVVRNYGKLLVEMVSIVPDGVVCFFVSYSYMDGIIATWNETGILKEIMQQKL 566

  Fly   589 IFLEPRSKDQFTSTMEEFYQAIRDSKGAVFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDP 653
            :|:|.:...:.|..::.:.:|....:||||.:|.||||:||:||....||.|::.|:||......
plant   567 VFIETQDVVETTLALDNYRRACDCGRGAVFFSVARGKVAEGIDFDRHYGRLVVMYGVPFQYTLSK 631

  Fly   654 KVILKRRYL-EANRTRENQLLSGQEWYNLDATRAVNQAIGRVIRHRNDYGAILLCDSRFKDASQV 717
            .:..:..|| :..:.:|...|:      .||.|...|.:|||||.:.|||.::..|.|:....:.
plant   632 ILRARLEYLHDTFQIKEGDFLT------FDALRQAAQCVGRVIRSKADYGMMIFADKRYSRHDKR 690

  Fly   718 QQLSKWIRGHLGDRPQCSPFGPIVRELRQFFKNAEANMKLPDERETDSPLETVCKTED 775
            .:|..||..||.|..........:...|:|.:    .|..|.::......:|:...||
plant   691 SKLPGWILSHLRDAHLNLSTDMAIHIAREFLR----KMAQPYDKAGTMGRKTLLTQED 744

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4078	NP_001259262.1	rad3	10..742	CDD:273169	185/799 (23%)
		DEAD_2	111..274	CDD:284209	51/184 (28%)
		Helicase_C_2	546..725	CDD:290046	56/179 (31%)
		HN_RTEL1	896..985	CDD:259826
UVH6	NP_171818.1	rad3	7..714	CDD:273169	185/800 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186062at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820