Protein Alignment Rtel1 and rtel1

DIOPT Version :10

• Sequence 1: NP_572254.1
• Gene: Rtel1 / 31497
• FlyBaseID: FBgn0029798
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: XP_031750114.1
• Gene: rtel1 / 100487920
• XenbaseID: XB-GENE-6035930
• Length: 1269
• Species: Xenopus tropicalis
• Alignment Length: 1038
• Identity: 394/1038 - (37%)
• Similarity: 574/1038 - (55%)
• Gaps: 127/1038 - (12%)

  Fly     1 MPESLIAGIPVHFPFEPYPVQRAYMEKVIHCLRDGTNGVLESPTGTGKTLSLLCSSLAWIRTRQS 65
            ||:..:||:.|.|||:||..|..||.|||.||:.|.||||||||||||||.|||::|||     .
 Frog     1 MPQVPVAGLTVDFPFQPYKCQEDYMGKVIQCLQQGVNGVLESPTGTGKTLCLLCATLAW-----R 60

  Fly    66 EHQKQMV-------KMEKAD-FSGLGGGAPGGDLSELAKTMGRANNW--GVPKVIYASRTHSQLT 120
            :|.|..:       :|..|: |......|.||     |...|:|:.:  .|||:|||||||||||
 Frog    61 QHYKDGISARKIAERMNGAELFPERPAAAWGG-----ASAEGQASAYYSDVPKIIYASRTHSQLT 120

  Fly   121 QAMRELKRTAYANMRSVVLGSRDQLCIHPEVMREQGNSNKTNMCKLRVHSKTCSFQMRVESRKDH 185
            |.:.|||.|.| ..:..|||||:||||||||.:::.|..|.:||:.:|.::||.|...||.:...
 Frog   121 QVISELKHTVY-RPKVCVLGSREQLCIHPEVKKQESNHAKVHMCRSKVSTRTCHFYNNVEEKSTE 184

  Fly   186 PDLRGPTIMDIEDLVKVGQRLKICPYFASRELVPQADITFMPYNYLLDPKARKANKIELGNTIVI 250
            .||.. .|:|||||||.|.:.:.|||:.||.|..||||.|||||||||||:|:|:.|:|..|:||
 Frog   185 KDLTN-HILDIEDLVKSGTKHRACPYYLSRNLKQQADIIFMPYNYLLDPKSRRAHNIDLKGTVVI 248

  Fly   251 LDEAHNIEKICEESASVQIKSSDVAMAIEDVTHIMQVFASGESQDMAGDEPK----DFTLD---- 307
            .|||||:|::||:|:|..:...|:|..|:.:..:::       :.|...|.|    :|.:|
 Frog   249 FDEAHNVERMCEDSSSFDLTPYDLASGIDAMDLVLK-------EQMENVEQKRYQAEFNMDSQSS 306

  Fly   308 -------DLTLLKEMLLELEKAIDAIVVDNAVDGTTFPASMMYELLGKANFTYGNVATIVSLLDK 365
                   ||..:|..|::||.:|::..:.....|.|...|.:::|...:..|:...|.::..|::
 Frog   307 GLTLELEDLAKVKAALMQLENSIESTQLPPGGGGVTKVGSYIFQLFAASGITFDTKAKLLESLEQ 371

  Fly   366 LVQYLLVASQQMSIRKGGTFT------LLSDLLTIVF-------ANKEDVMSKVYASFKVHVLVE 417
            ::|::..:|        |.||      .|:|::.|||       ||.......:...:|||:..:
 Frog   372 IIQHVGGSS--------GIFTNTMGLQKLADIIQIVFSMEPPEGANVSSFNQNISKYYKVHIHPD 428

  Fly   418 ESKQGHGKQQG-----AKQQGGWLGKGTIAAATGLSKVAKIINFWCFNPGFGMEQLLNTQVRSVI 477
            .:::  .|.:|     :|:|||                 |::::|||:||:.|..|:...||.||
 Frog   429 TNQR--KKPRGDVWSNSKKQGG-----------------KVLSYWCFSPGYTMHDLVRQGVRCVI 474

  Fly   478 LTSGTLAPLKPLIAELAIPVAQHLENPHIVDQSQVYVKIIGTGPDRQQLISNYANRDNPKYISSL 542
            ||||||.||.....|:.||....|||||::|:.|::|.|:..|||..||.|:|..|.:.:|:|||
 Frog   475 LTSGTLCPLSSFTMEMQIPFPVSLENPHVIDKHQIWVGIVPRGPDGSQLSSSYDRRFSEEYLSSL 539

  Fly   543 GQTILNVARIVPDGLLVFFPSYPMLNKCVDAWQASGLWADISCKKPIFLEPRSKDQFTSTMEEFY 607
            |:||.|:||:||.||||||||||:|:|.::.|:..||.|.|...||:|:|||.|..||..::.:|
 Frog   540 GKTIGNIARVVPHGLLVFFPSYPVLDKSIEFWKERGLSAKIDDVKPMFVEPRGKGSFTEVIDAYY 604

  Fly   608 QAIR--DSKGAVFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDPKVILKRRYLEANRTREN 670
            :.||  :..||.|:||||||.||||||||.|||.||||||||||..||:|:||.::|:..|..:.
 Frog   605 EKIRSANGSGASFLAVCRGKASEGLDFADNNGRGVIITGLPFPPRMDPRVVLKMQFLDEMRRSQG 669

  Fly   671 Q---LLSGQEWYNLDATRAVNQAIGRVIRHRNDYGAILLCDSRFKDASQVQQLSKWIRGHLGDRP 732
            .   .|||||||...|:||||||||||||||||||||.|||.||..:....||..|:|.::....
 Frog   670 SAGLYLSGQEWYRQQASRAVNQAIGRVIRHRNDYGAIFLCDHRFNQSDARAQLPSWVRPYVRTYD 734

  Fly   733 QCSPFGPIVRELRQFFKNAEANMKLP----DERETDSPLETVCKTEDEPLAAIPKVKREPGSNAT 793
            .   ||.|:|::.|||:.|...|..|    |::|...||.........|:|  |...||....|.
 Frog   735 N---FGHIIRDVSQFFRVALKIMPTPTLHSDQKEGPVPLIGCSSQSPRPVA--PSSSREAPKKAK 794

  Fly   794 FKSANESAIKVEMANSIKTWTPADYASAAGHKLGGAAPNAMDFMSRLDSNVSSIDFNCCTDSKSG 858
            ...::..::|.:.........|.........::..::......:..|:.:...:.     :.|:|
 Frog   795 TLDSHVPSLKRKRDECSSEVVPGSVCEGYEQEVPMSSQRPAGLLDALEHSEKRVQ-----EEKAG 854

  Fly   859 SSGLVKIHKRERSSPTAPESSSQVT------KKRYKLVENIKVEPSSSQAKEAPEERAAFLRELR 917
                   .|..|.|..:.:...::.      |::.|:|:|...|.:|.|...:   .:.||..::
 Frog   855 -------EKVSRLSTLSLQYDKRLADEQRGGKRKIKIVQNRAPEDTSDQKMTS---ASLFLVSVK 909

  Fly   918 SLVTQDQFRRFGKALLEYKNGTYESFQALMAILLDVLSAPKVRY-MLVGMRKYLKNEHKDEFD 979
            ..::|:.:..|..|:.|||..  ...|.|::.|..:......:| :|.|..::::.:||.|||
 Frog   910 QSLSQENYGTFMAAMTEYKKN--NDLQQLISHLRTLFCQDPAKYNLLRGFYQFIRPQHKLEFD 970

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtel1	NP_572254.1	rad3	10..742	CDD:273169	339/779 (44%)
		HN_RTEL1	896..985	CDD:259826	22/85 (26%)
rtel1	XP_031750114.1	rad3	8..741	CDD:273169	340/781 (44%)
		HN_RTEL1	881..981	CDD:259826	25/95 (26%)
		HN_RTEL1	1028..1128	CDD:259826
		RING_Ubox	1207..1256	CDD:473075