Protein Alignment IntS6 and SAGE1

DIOPT Version :9

• Sequence 1: NP_001259259.1
• Gene: IntS6 / 31496
• FlyBaseID: FBgn0261383
• Length: 1284
• Species: Drosophila melanogaster
• Sequence 2: NP_001368831.1
• Gene: SAGE1 / 55511
• HGNCID: 30369
• Length: 904
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 101/509 - (19%)
• Similarity: 171/509 - (33%)
• Gaps: 164/509 - (32%)

  Fly   841 TSDQDTPLNGYVH----------------NFINGISDDAETGETEAVPGGASLPGASS----ANE 885
            |.||...:|.:||                |.::|:.:.|          |||:|..||    |..
Human   430 TRDQYATVNHHVHEARMENGQRKQDNVLSNVLSGLINMA----------GASIPAMSSRDLYATI 484

  Fly   886 PSSIGASPAVSATPATSVIPASNGSEVCSAVAAGSSSSISS------------------------ 926
            ..|:......|..|.|..: .||.:.....:|||...|:|:
Human   485 THSVREEKMESGKPQTDKV-ISNDAPQLGHMAAGGIPSMSTKDLYATVTQNVHEERMENNQPQPS 548

  Fly   927 ---SASSPGVLYVPLNGL-----------TTHAAYSSNLGGPSSPLDNLSS------LGGAAGGG 971
               |...||:.|:.:.|:           .||..:...:....:..||:.|      :..||
Human   549 YDLSTVLPGLTYLTVAGIPAMSTRDQYATVTHNVHEEKIKNGQAASDNVFSTVPPAFINMAA--- 610

  Fly   972 GSGLLGVSKPGSLPLANGYGHGHSSAI-----------SPPSPLSLVPLSPLGTSTPAASSSGLS 1025
                .|||   |:...:.|     :|:           |.|:|.:::..:|......||  :|:|
Human   611 ----TGVS---SMSTRDQY-----AAVTHNIREEKINNSQPAPGNILSTAPPWLRHMAA--AGIS 661

  Fly  1026 SSSAYFSHNDINDASEISRILQTCHNG----TSSGSSVGAGASNSNLNGNGSTESGGGVSSDDHA 1086
            |:..    .|:...:..|...:...||    .:|.|:|..|..|.         ||.|:|.....
Human   662 STIT----RDLYVTATHSVHEEKMTNGQQAPDNSLSTVPPGCINL---------SGAGISCRSTR 713

  Fly  1087 SLGGNSFDALKRTAGTAGSTAAGNPHYYWASGLNHHNNNNSSAAGAASGSTLSNNHNHRGHNNSS 1151
            .|.......::.                     ....|:.:...|..|.|......|..|| ...
Human   714 DLYATVIHDIQE---------------------EEMENDQTPPDGFLSNSDSPELINMTGH-CMP 756

  Fly  1152 PNKLEVKINSSCGSS-------PTHNNGGMGSPGQS----------LPLIFT-----EEQREAAR 1194
            ||.|:...:.....|       |..|...:|:...|          :.|:.|     :.....|:
Human   757 PNALDSFSHDFTSLSKDELLYKPDSNEFAVGTKNYSVSAGDPPVTVMSLVETVPNTPQISPAMAK 821

  Fly  1195 LHNVELRLQIFRDIRRPGRDYSQLLEHLNLVKGDQDMQSDFVDMCIVESLRFRR 1248
            ..|.:::.|:.:::||.|::|.::...|..|:|...::..||:..|.|:.||::
Human   822 KINDDIKYQLMKEVRRFGQNYERIFILLEEVQGSMKVKRQFVEFTIKEAARFKK 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS6	NP_001259259.1	vWFA	4..>147	CDD:238119
		INT_SG_DDX_CT_C	1196..1257	CDD:291946	15/53 (28%)
SAGE1	NP_001368831.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..72
		INT_SG_DDX_CT_C	823..884	CDD:405888	15/53 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160432
Domainoid	1	1.000	42	1.000	Domainoid score	I12419
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12957
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.030