DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Snx27 and MDM1

DIOPT Version :9

Sequence 1:NP_727023.1 Gene:Snx27 / 31493 FlyBaseID:FBgn0052758 Length:531 Species:Drosophila melanogaster
Sequence 2:NP_013603.1 Gene:MDM1 / 854867 SGDID:S000004572 Length:1127 Species:Saccharomyces cerevisiae


Alignment Length:347 Identity:79/347 - (22%)
Similarity:125/347 - (36%) Gaps:93/347 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   166 RSLPISIPDYGIVN-RNGER---YIVFNI-HMAGRQLCS----RRYREFANLHSLLRKEFSGFN- 220
            |...|.|..|...| .||.:   |.:.|| |....|:.|    |||.||..|::.|:|.|.... 
Yeast   780 RKTKIYIRSYFSENSSNGLKEITYYIINIHHFNNGQVSSWDMARRYNEFFELNTYLKKNFRDLMR 844

  Fly   221 -----FP-KLPGKWPFQLSEQQL-DTRRRGLEQYLEKVCAVRVIAESDAVQDFLTD--------- 269
                 || |:.....:.:::..| :.|::.||:||.::.::..|.|.:..:.||||         
Yeast   845 QLQDLFPSKVKMSLKYHVTKTLLYEERKQKLEKYLRELLSISEICEDNIFRRFLTDPTPFKLNKE 909

  Fly   270 -TEDDISASPVDIKVMLPDHEVSTVSVKKSSNAQVV-WEILVQRANLTAY-TQQYFYLFEIVEYN 331
             ..|||...|:        ||....|...|:::.|| .:.......|..| .:::|:.       
Yeast   910 YMHDDILEEPL--------HEPIGSSNSTSNSSSVVDLQSSEDGGELNFYEDERHFFT------- 959

  Fly   332 FERKLQPHEIPHQLYVQNYSTASSTCLCVRRWLFSVAKELTLPDGEQAGRFIFYQAVDEVNRGNI 396
                    :..:..|.||.|.....|                      ..||...|:::.|.|.:
Yeast   960 --------DSGYPFYSQNKSFVKQIC----------------------DLFISLFALNKANAGWL 994

  Fly   397 RADGRLYELKALQDAKKAGDYLALARTLPGYGDVVFPHCSCDSRKEGHVVPAVGMKSFRLHACRE 461
            |....:..|:.|           |..|:..|..|.....    |.|..|..|:  .:|:.....:
Yeast   995 RGRAIITVLQQL-----------LGSTIEKYIKVSIQKL----RSEDQVFEAI--VTFKNMLWGD 1042

  Fly   462 DGSLEAQMVELTWDSITRSESD 483
            :|..|.:..|..  ..||||.:
Yeast  1043 NGLFERKRNETA--EATRSEGE 1062

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Snx27NP_727023.1 PDZ_signaling 46..138 CDD:238492
PX_SNX27 165..270 CDD:132796 37/130 (28%)
UBQ 278..363 CDD:294102 15/86 (17%)
FERM-like_C_SNX27 428..528 CDD:270146 13/56 (23%)
MDM1NP_013603.1 PXA 85..276 CDD:214611
RGS 462..567 CDD:413378
PX_MDM1p 763..900 CDD:132786 35/119 (29%)
Nexin_C 993..1106 CDD:400794 19/89 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1370
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

Return to query results.
Submit another query.