DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx27 and SNX13

DIOPT Version :9

Sequence 1:	NP_727023.1	Gene:	Snx27 / 31493	FlyBaseID:	FBgn0052758	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001337791.1	Gene:	SNX13 / 23161	HGNCID:	21335	Length:	968	Species:	Homo sapiens

Alignment Length:	122	Identity:	36/122 - (29%)
Similarity:	58/122 - (47%)	Gaps:	20/122 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 YIDYSDKRSLPISIPDYGIVNRNGERYIVFNIHMAGRQLCS-------RRYREFANLHSLLRKEF 216
            |.||.     |.::.  |:.|.:|:.|.::.|.:..|.|.|       |||.:|.:.|..:.::|
Human   570 YADYD-----PYAVA--GVCNDHGKTYALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQF 627

  Fly   217 SGF-NFPKLPGKWPF-QLSEQQLDTRRRGLEQYLEKVCAVRVIAESDA----VQDFL 267
            ... :..|||||..| .:....|:.|::.|..||:.:.|..::..|.|    |.|||
Human   628 ESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMKASPALAHYVYDFL 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx27	NP_727023.1	PDZ_signaling	46..138	CDD:238492
		PX_SNX27	165..270	CDD:132796	33/116 (28%)
		UBQ	278..363	CDD:294102
		FERM-like_C_SNX27	428..528	CDD:270146
SNX13	NP_001337791.1	PXA	97..284	CDD:214611
		RGS_SNX13	377..511	CDD:188674
		PX_SNX13	557..687	CDD:132783	36/122 (30%)
		Nexin_C	803..911	CDD:312222
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1370
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030