Protein Alignment CG33080 and ROT2

DIOPT Version :9

• Sequence 1: NP_788858.1
• Gene: CG33080 / 31491
• FlyBaseID: FBgn0053080
• Length: 925
• Species: Drosophila melanogaster
• Sequence 2: NP_009788.3
• Gene: ROT2 / 852530
• SGDID: S000000433
• Length: 954
• Species: Saccharomyces cerevisiae
• Alignment Length: 689
• Identity: 132/689 - (19%)
• Similarity: 244/689 - (35%)
• Gaps: 223/689 - (32%)

  Fly   395 SLSYANFDFAPYASGDSKIHQFGN--GVKRYFINSIGVAMQVSEKTPLQLGVNRTE--------- 448
            |||.:..|.....:||..:..|..  .:|.|:.|::  .:.|:|:..|.:..:||:
Yeast   170 SLSNSTADTFHLRNGDVSVEIFAEPFQLKVYWQNAL--KLIVNEQNFLNIEHHRTKQENFAHVLP 232

  Fly   449 -----NRF---CLRAAND-----------EFTFV---------NHLTPLPQLD------------ 473
                 |.|   .|.:.:|           :|:|:         .|.|.|..:|
Yeast   233 EETTFNMFKDNFLYSKHDSMPLGPESVALDFSFMGSTNVYGIPEHATSLRLMDTSGGKEPYRLFN 297

  Fly   474 -----YRICTTEDM-RSLHMLMTQQS----------LWDGLKEQEFK---VLHSLLEEPVWRIPH 519
                 |.|.|::.| .|:..:.:..|          .|..:|....|   :.|.:.|..|..:..
Yeast   298 VDVFEYNIGTSQPMYGSIPFMFSSSSTSIFWVNAADTWVDIKYDTSKNKTMTHWISENGVIDVVM 362

  Fly   520 T---ELPESLNE-------------SAI----C--DYSESAIAMGL-----GHIVINEF-W--QE 554
            :   ::|..:::             |:|    |  :|::....:.:     .|::..:| |  .|
Yeast   363 SLGPDIPTIIDKFTDLTGRPFLPPISSIGYHQCRWNYNDEMDVLTVDSQMDAHMIPYDFIWLDLE 427

  Fly   555 NIGD---FTVDKARFPTLKDTIDVLHRRGFKVVLTIQPFISTDSANFKDAVKRKLLIYERHSERS 616
            ...|   ||..:..||..|..:..|.:.|..:|:.|.|.:..|              || .|:|.
Yeast   428 YTNDKKYFTWKQHSFPNPKRLLSKLKKLGRNLVVLIDPHLKKD--------------YE-ISDRV 477

  Fly   617 IPALTRYKSSSSAGVLDITNNASVP--------WLLEKLQRLKEEYGV---QSFY---------- 660
            |        :.:..|.|...|..|.        | ::.:.:    ||.   :||:
Yeast   478 I--------NENVAVKDHNGNDYVGHCWPGNSIW-IDTISK----YGQKIWKSFFERFMDLPADL 529

  Fly   661 --LDLGTGYNLPHYYQCRQTLDNPDTYA----------------RLFTASLEGAGLMAV-STASV 706
              |.:....|.|..:      |.|:|.|                .::..|:..|...|: |..|.
Yeast   530 TNLFIWNDMNEPSIF------DGPETTAPKDLIHDNYIEERSVHNIYGLSVHEATYDAIKSIYSP 588

  Fly   707 VPKPP------TFLSTPPANATWEG--------LRETLGAVLNYGVIGYPFVLPGVIGGDYLLQR 757
            ..|.|      .|..:....|||.|        |:.::..||:..:.|.||     ||.|
Yeast   589 SDKRPFLLTRAFFAGSQRTAATWTGDNVANWDYLKISIPMVLSNNIAGMPF-----IGAD----- 643

  Fly   758 PLSKMVSFYSLSQPPLPDPELFIRWLQLATFMPAMQ-FSHLPSEYR-----SDLVTRVAQELKEV 816
                 ::.::..    |.|||..||.|...:.|..: .:|:.::.|     ::.:..:.:::.::
Yeast   644 -----IAGFAED----PTPELIARWYQAGLWYPFFRAHAHIDTKRREPYLFNEPLKSIVRDIIQL 699

  Fly   817 RQLIVIPLLKKYLNPSMNEGLPLVRPLWMMDPHDPACLIVSDEFSVGEE-LIVAPILHANREERE 880
            |..: :|.|....:.|...|.|::.|:::..|.......:.::|..... |:|.|:....:.|.|
Yeast   700 RYFL-LPTLYTMFHKSSVTGFPIMNPMFIEHPEFAELYHIDNQFYWSNSGLLVKPVTEPGQSETE 763

  Fly   881 VYLPQGVWKD--GIDGSLRKGSRWMH-GYRVPKDKIAYF 916
            :..|.|::.:  .:...:..|:..:. ....|.|||..|
Yeast   764 MVFPPGIFYEFASLHSFINNGTDLIEKNISAPLDKIPLF 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33080	NP_788858.1	GH31_NET37	511..888	CDD:269878	91/470 (19%)
ROT2	NP_009788.3	GH31_N	259..380	CDD:270212	19/120 (16%)
		GH31_GANC_GANAB_alpha	380..850	CDD:269889	94/477 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810