DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33080 and Myorg

DIOPT Version :9

Sequence 1:	NP_788858.1	Gene:	CG33080 / 31491	FlyBaseID:	FBgn0053080	Length:	925	Species:	Drosophila melanogaster
Sequence 2:	NP_001078984.1	Gene:	Myorg / 329828	MGIID:	2140300	Length:	716	Species:	Mus musculus

Alignment Length:	705	Identity:	191/705 - (27%)
Similarity:	322/705 - (45%)	Gaps:	68/705 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 KKRETKDYKIKIFVIIMFFIIIFLIGYAYVAYHQQV------------LTRSYFQKIKFNSHDRI 294
            |.:.||:.:..:...::..:::.....|:..|...:            |.|..| .|:....:::
Mouse    46 KPKPTKELRPLLCSAVLGLLLVLAAVVAWCYYSASLRKAERLRAELLDLNRGGF-SIRNQKGEQV 109

  Fly   295 FRILSHEDKEVISGQLGV-TLGFDTAPFHCLEEQRRSDGSVCIEWNGVARLHL---NFEDKGVFR 355
            ||:...      ||.|.: :...|.|...|   .|.:||         ..||.   ....|....
Mouse   110 FRLAFR------SGALDLDSCSRDGALLGC---SRAADG---------RPLHFFIQTVRPKDTVM 156

  Fly   356 CYTLQWQALTPGLLPTDCYELKRDNGLWFGGGVTKGQEWSLSY-ANFDFAPYASGD--SKIHQFG 417
            ||.::|:...||........|......|:||...:.|.|.:.. ...:..|:.:.|  |....||
Mouse   157 CYRVRWEEAVPGRAVEHAMFLGDAAAHWYGGAEMRTQHWPIRLDGQQEPQPFVTSDVYSSDAAFG 221

  Fly   418 NGVKRYFINSIGVAMQVSEKTPLQLGVNRTENRFCLRAANDEFTFVNHL--TPLPQLDYRICTTE 480
            ..::||:::|...|::|::..|..||.|.||....|:|...:.::....  |..|:|.||:|...
Mouse   222 GILERYWLSSRAAAIKVNDSVPFHLGWNSTERSMRLQARYHDTSYKPPAGRTAAPELSYRVCVGS 286

  Fly   481 DMRSLHMLMTQQSLWDGLKEQEFKVLHS-LLEEPVWR--IPHTELPESLNESAICDYSES--AIA 540
            |:.|:|..|.::..     .:..:|..| ...:|:|.  ..|   ..:::::.:..:::.  ...
Mouse   287 DVTSIHKYMVRRYF-----NKPSRVPASEAFRDPIWSTWALH---GRAVDQNKVLQFAQQIRQHR 343

  Fly   541 MGLGHIVINEFWQENIGDFTVDKARFPTLKDTIDVLHRRGFKVVLTIQPFISTDSANFKDAVKRK 605
            ....|:.|::.:....|||..|:.:||...|....|...||:|.|.:.||::.:|::|.:.|:|:
Mouse   344 FNSSHLEIDDMYTPAYGDFNFDEGKFPNASDMFRRLRDAGFRVTLWVHPFVNYNSSSFGEGVERE 408

  Fly   606 LLIYERHSERSIPALTRYKSSSSAGVLDITNNASVPWLLEKLQRLKEEYGVQSFYLDLGTGYNLP 670
            |.:  |.....:|||.|:.:...| |||.|:..:..|....|:||:..|.|.||..|.|....||
Mouse   409 LFV--REPTGRLPALVRWWNGIGA-VLDFTHPEAREWFQGHLRRLRLRYNVTSFKFDAGEVSYLP 470

  Fly   671 HYYQCRQTLDNPDTYARLFTASLEG-AGLMAVSTASVVPKPPTFLSTPPANATWE---GLRETLG 731
            ..:...:.|.:|..::|.:|...|. ..|..|...........|......::.|.   |||..:.
Mouse   471 RDFSTYRPLSDPSVWSRRYTEMAEPFFSLAEVRVGYQSQNISCFFRLVDRDSVWGYDLGLRSLIP 535

  Fly   732 AVLNYGVIGYPFVLPGVIGGDYLLQRPLSKMVSFYSLSQPPLPDPELFIRWLQLATFMPAMQFSH 796
            |||...::||||:||.:|||:.:.:|...:       ...|.|:.||::|||::|.||||||||.
Mouse   536 AVLTVSMLGYPFILPDMIGGNAVPERTAGR-------QDGPGPERELYVRWLEVAAFMPAMQFSI 593

  Fly   797 LPSEYRSDLVTRVAQELKEVRQLIVIPLLKKYLNPSMNEGLPLVRPLWMMDPHDPACLIVSDEFS 861
            .|.:|.:::|. :|.:...:|..:|.|||.:......:.|.|:|||||.:.|.|.....:..:|.
Mouse   594 PPWQYDAEVVA-IAHKFAALRASLVAPLLLELAGEITDTGDPIVRPLWWIAPGDETAHRIDSQFL 657

  Fly   862 VGEELIVAPILHANREEREVYLPQGVWKDGIDGSLRKGSRWMHGYRVPKDKIAYF 916
            :|:.|:|||:|...::||:||||.|.|:........|....:..|.|..|::|||
Mouse   658 IGDTLLVAPVLEPGKQERDVYLPAGKWRSYKGELFDKTPVLLTDYPVDLDEVAYF 712

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33080	NP_788858.1	GH31_NET37	511..888	CDD:269878	119/384 (31%)
Myorg	NP_001078984.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
Myorg	NP_001078984.1	GH31_NET37	313..684	CDD:269878	119/384 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5596
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004094
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103615
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.660