Protein Alignment CG33080 and Gaa

DIOPT Version :9

• Sequence 1: NP_788858.1
• Gene: CG33080 / 31491
• FlyBaseID: FBgn0053080
• Length: 925
• Species: Drosophila melanogaster
• Sequence 2: NP_001152796.1
• Gene: Gaa / 14387
• MGIID: 95609
• Length: 953
• Species: Mus musculus
• Alignment Length: 917
• Identity: 185/917 - (20%)
• Similarity: 304/917 - (33%)
• Gaps: 273/917 - (29%)

  Fly    91 NSI----SMPSGINALDLEALRLRHQM-QPQDALHEEIIADDATSSLGTPATPD-----TPG--- 142
            ||:    ::.|...|:.|..|.||..| .||| |||      ::|.|.....|.     .||
Mouse    10 NSVVGACTLISLTTAVILGHLMLRELMLLPQD-LHE------SSSGLWKTYRPHHQEGYKPGPLH 67

  Fly   143 --------TTAPTTTANTPDKAINFANDDSDDEFGNARRPVHRDRFRSRRRASIAPLPALRLNSK 199
                    ..|||.....|....:.|.|          :.:.:::..:|   ....:||.::..:
Mouse    68 IQEQTEQPKEAPTQCDVPPSSRFDCAPD----------KGISQEQCEAR---GCCYVPAGQVLKE 119

  Fly   200 EMLAS----------DFDSHSLASNQASITSVNSLASLLREKMQAFPQLIRKKKRETKDYKIKIF 254
            ..:..          .:...:|:|.::..|     |:|.|.....||          ||......
Mouse   120 PQIGQPWCFFPPSYPSYRLENLSSTESGYT-----ATLTRTSPTFFP----------KDVLTLQL 169

  Fly   255 VIIMFFIIIFLIGYAYVAYHQQVLTRSYFQKIKFNSHDRIF------RILSHEDKEVISGQLGVT 313
            .::|                 :..:|.:| |||..:..|..      |:||.....:.|
Mouse   170 EVLM-----------------ETDSRLHF-KIKDPASKRYEVPLETPRVLSQAPSPLYS------ 210

  Fly   314 LGFDTAPFHCLEEQRRSDGSVCIEWNGVARLHLNFEDKGVFRCYTLQWQALT-------PGLLPT 371
            :.|...||..: .:|:..|.|.:. ..||.|.  |.|:.:....:|..|.:|       |.:|.|
Mouse   211 VEFSEEPFGVI-VRRKLGGRVLLN-TTVAPLF--FADQFLQLSTSLPSQHITGLGEHLSPLMLST 271

  Fly   372 DCYELKRDNGLWFGGGVTKGQEWSLSYANFDFAPYASGDSKIHQFGNGVKRYFINSIGVAMQVSE 436
            |...:.    ||                |.|..|           ..|...|..:...:|:   |
Mouse   272 DWARIT----LW----------------NRDTPP-----------SQGTNLYGSHPFYLAL---E 302

  Fly   437 KTPLQLGVNRTENRFCLRA-ANDEFTFVNHLTPLPQLDYRICTTEDMRSLHMLMTQQSLWDGLKE 500
            ...|..||      |.|.: |.|..     |.|.|.|.:|  :|..:..:::.:..:.  ..:.:
Mouse   303 DGGLAHGV------FLLNSNAMDVI-----LQPSPALTWR--STGGILDVYVFLGPEP--KSVVQ 352

  Fly   501 QEFKVLHSLLEEPVWRIP-HTELPESLNESAIC--DYSESAIA------MGLGHIVINEFW---- 552
            |...|:......|.|.:. |           :|  .||.:||.      |...|..::..|
Mouse   353 QYLDVVGYPFMPPYWGLGFH-----------LCRWGYSSTAIVRQVVENMTRTHFPLDVQWNDLD 406

  Fly   553 -QENIGDFTVDKARFPTLKDTIDVLHRRGFKVVLTIQPFISTDSAN-------FKDAVKRKLLIY 609
             .:...|||.::..|....|.:..||:.|.:.::.:.|.||  ||.       :.:.::|.:.|.
Mouse   407 YMDARRDFTFNQDSFADFPDMVRELHQDGRRYMMIVDPAIS--SAGPAGSYRPYDEGLRRGVFIT 469

  Fly   610 ERHSERSI----PALTRYKSSSSAGVLDITNNASVPWLLEKLQRLKEEYGVQSFYLDLGTGYNLP 670
            ....:..|    |..|.:.        |.||..::.|..:.:.....:......:||:....|..
Mouse   470 NETGQPLIGKVWPGTTAFP--------DFTNPETLDWWQDMVSEFHAQVPFDGMWLDMNEPSNFV 526

  Fly   671 HYYQ--C-RQTLDNPDTYARLFTASLEGAGLMAVS------------------------------ 702
            ...|  | ...|:||.....:....|:.|.:.|.|
Mouse   527 RGSQQGCPNNELENPPYVPGVVGGILQAATICASSHQFLSTHYNLHNLYGLTEAIASSRALVKTR 591

  Fly   703 -TASVVPKPPTFLS--------TPPANATWEGLRETLGAVLNYGVIGYPFVLPGVIG--GDYLLQ 756
             |...|....||..        |....::||.|..::..:|.:.::|.|.|...:.|  ||
Mouse   592 GTRPFVISRSTFSGHGRYAGHWTGDVRSSWEHLAYSVPDILQFNLLGVPLVGADICGFIGD---- 652

  Fly   757 RPLSKMVSFYSLSQPPLPDPELFIRWLQLATFMPAMQ----FSHLPSE-YRSDLVTRVAQELKEV 816
                             ...||.:||.||..|.|.|:    .:.:|.| ||.....:.|......
Mouse   653 -----------------TSEELCVRWTQLGAFYPFMRNHNDLNSVPQEPYRFSETAQQAMRKAFA 700

  Fly   817 RQLIVIPLLKKYLNPSMNEGLPLVRPLWMMDPHDPACLIVSDEFSVGEELIVAPILHANREEREV 881
            .:..::|.|....:.:...|..:.|||::..|.||:...|..:...|..|::.|:|...:.|...
Mouse   701 LRYALLPYLYTLFHRAHVRGDTVARPLFLEFPEDPSTWSVDRQLLWGPALLITPVLEPGKTEVTG 765

  Fly   882 YLPQGVW 888
            |.|:|.|
Mouse   766 YFPKGTW 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33080	NP_788858.1	GH31_NET37	511..888	CDD:269878	92/450 (20%)
Gaa	NP_001152796.1	Trefoil	82..130	CDD:278515	6/60 (10%)
		NtCtMGAM_N	147..253	CDD:293468	30/148 (20%)
		GH31_N	246..359	CDD:270212	31/161 (19%)
		Glyco_hydro_31	340..825	CDD:279404	95/477 (20%)
		GH31_MGAM_SI_GAA	359..717	CDD:269888	76/399 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810