DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33080 and gaa2

DIOPT Version :9

Sequence 1:	NP_788858.1	Gene:	CG33080 / 31491	FlyBaseID:	FBgn0053080	Length:	925	Species:	Drosophila melanogaster
Sequence 2:	XP_009304541.2	Gene:	gaa2 / 100332784	ZFINID:	ZDB-GENE-130530-749	Length:	966	Species:	Danio rerio

Alignment Length:	815	Identity:	158/815 - (19%)
Similarity:	260/815 - (31%)	Gaps:	255/815 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 DFDSHSLASNQASITSVNSLASLLREKMQAFPQLIRKKKRET-----------------KDYKIK 252
            |:.|:.|.|  ...|.:..:..|||.|...:|:.|...:.|.                 |.|::.
Zfish   164 DYPSYELMS--IVDTEMGKVGKLLRNKKTYYPKDIDALQLEVLFEEDHRLRVKITDPTEKRYEVP 226

  Fly   253 IFVIIMFFIIIFLIGYAYVAYHQQVLTRSY---FQKIKFNSHDRIFRILSHEDKEVISGQLGVTL 314
            |.|.::               |::....||   |.|..|.      .|:    |...:|  .|.|
Zfish   227 IDVPVV---------------HKRASNPSYTVDFIKEPFG------LIV----KRTQTG--AVLL 264

  Fly   315 GFDTAPFHCLEEQRRSDGSVCIEW-NGVARLHLNFEDKGVFRCYTLQWQALTPGLLPTDCYELKR 378
            ....||....::..:...|:...: .|:.....||       .:.:||..||
Zfish   265 NTSIAPLFYADQFLQMSSSLPTRFIYGLGEHRSNF-------LHDVQWNTLT------------- 309

  Fly   379 DNGLWFGGGVTKGQEWSLSYANFDFAPYASGDSKIHQFGNGVKRYFINS--IGVAMQVSEKTPLQ 441
               :|  .......|.:..|....|......|...|.|      :.:||  :.|.:|.:.....:
Zfish   310 ---MW--ARDVPPMELTNLYGVHPFYLSMESDGNAHGF------FMLNSNAMDVVLQPAPAVTWR 363

  Fly   442 L--GVNRTENRFCLRAANDEFTFVNHLTPLPQ--------------------LDYRICTTEDMRS 484
            :  |:               ..|...|.|.|.                    |.|.:|...
Zfish   364 MIGGI---------------LDFYIFLGPDPSSVIGQYLDVVGKPAMPIYWALGYHLCRWG---- 409

  Fly   485 LHMLMTQQSLWDGLKEQEFKVLHSLLEEPVWRIPHTELPESLNESAICDYSESAIAMGLGHIVIN 549
               ..|....|..:||..                :..:|:.:..:.| ||.:.::
Zfish   410 ---YKTSNKTWSVVKEMR----------------NYGIPQDVQWNDI-DYMDRSL---------- 444

  Fly   550 EFWQENIGDFTVDKARFPTLKDTIDVLHRRGFKVVLTIQPFISTDSA-----NFKDAVKRKLLIY 609
                    |||.|.:.|.||.|.:..|.|.....|:.:.|.||....     .|.:..|:.:.|.
Zfish   445 --------DFTYDPSGFSTLPDLVKDLQRHDQHYVMILDPGISNSQPPGSYWPFDEGKKKGIFIN 501

  Fly   610 ERHSERSI----PALTRYKSSSSAGVLDITNNASVPWLLEKLQRLKEEYGVQSFYLDLGTGYNLP 670
            :.:.:..|    |.||.:.        |.:|..:..|..:.|||...:......::|:    |.|
Zfish   502 DSNGDILIGKVWPGLTAFP--------DFSNPDTHEWWYQNLQRFHNKVPFDGVWIDM----NEP 554

  Fly   671 HYY------QCRQT-LDNPDTYARLFTASLEGA--------------------GLM-AVSTAS-- 705
            ..:      .|... |:||.....:...:|:|.                    ||| |.:|.|
Zfish   555 SNFFDGSLNGCPDNELENPPYTPGILGGTLKGKTVCASARQKISVHYNIHSLYGLMEAQATESAL 619

  Fly   706 --VVPKPPTFL--STPPA------------NATWEGLRETLGAVLNYGVIGYPFVLPGVIGGDYL 754
              :..|.|..:  ||.|:            .:.|:.|..::..:|.:.::|.|     :||.|
Zfish   620 RRITKKRPFIISRSTFPSQGKYSGHWLGDNRSQWKDLATSIPGMLTFNILGIP-----LIGAD-- 677

  Fly   755 LQRPLSKMVSFYSLSQPPLPDPELFIRWLQLATFMPAMQFSHLPSEYRSDLVT------RVAQEL 813
                   :..|...:     ..||.:||.||..|.|..: :|...:.:....|      |.|.:.
Zfish   678 -------ICGFGGST-----TEELCVRWTQLGAFYPFTR-NHNSIDEQDQEPTAFSPAARTAMKE 729

  Fly   814 KEVRQLIVIPLLKKYLNPSMNEGLPLVRPLWMMDPHDPACLIVSDEFSVGEELIVAPILHANREE 878
            ..:.:..:.|.|....:.:...|..:..||....|.|.....:..:|..|:.|:|.|:|.|.|:.
Zfish   730 AILLRYSLFPHLYTLFHHAHVSGHTVATPLLFQFPTDEKTYGIDKQFLWGKSLLVTPVLDAGRDY 794

  Fly   879 REVYLPQGVWKDGIDGSLRKGSRWMHGYRVPKDKI 913
            ...|.|:|:|.|...|:....|........|.|||
Zfish   795 VVGYFPKGLWYDFHTGNSLISSGEEIKLEAPADKI 829

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33080	NP_788858.1	GH31_NET37	511..888	CDD:269878	90/437 (21%)
gaa2	XP_009304541.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810