Protein Alignment AdamTS-B and adamts1

DIOPT Version :9

• Sequence 1: NP_572247.2
• Gene: AdamTS-B / 31490
• FlyBaseID: FBgn0029791
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: XP_021331598.1
• Gene: adamts1 / 565145
• ZFINID: ZDB-GENE-070814-1
• Length: 1026
• Species: Danio rerio
• Alignment Length: 1041
• Identity: 332/1041 - (31%)
• Similarity: 477/1041 - (45%)
• Gaps: 222/1041 - (21%)

  Fly    77 RQRRSLNSEHDTQAADLHLLLPLANETLHLELMAHSYFLAPNLVVERHRRDLRTRSPLT-----T 136
            :|.|..:||......|:.      .:.:.|.|.....||||..|.:      ....|.|     .
Zfish    42 KQSREEDSEKRIYRLDVF------GKRMVLALEPDQTFLAPGFVFQ------MVGKPETGEFDSA 94

  Fly   137 RHLNCHFHGKVRGQPATNVAISTCAGLVGHIRTAGNEYFIEPSKEHEPHPVNGHPHVVFQRSSVK 201
            ....|.|.|.|.|...::.||:.|.||.|.....|.||||:|...      .|       .::.:
Zfish    95 GEARCFFSGTVNGDELSSAAINLCKGLHGGFSVGGEEYFIQPENS------TG-------AATDR 146

  Fly   202 PKHSLRKRNKRKRGGKSGSGAEVSNCGTREPRRRMETRLEWQARGKVKVQGGRQIRRHHHHHHHH 266
            ..|::|:|.......:||     |.||..|
Zfish   147 DTHTIRRRTPGILAEESG-----SKCGVNE----------------------------------- 171

  Fly   267 HHKHKYRHHQQKISRVPHTKFKYETQFQTEPDHAEIPRRRRSISSPRHVETLIVADATMSAFH-R 330
                    .:::::..|||  .:....:::..|    |.||.:|:||::|.:||||.:|:.|| .
Zfish   172 --------EEERVTEKPHT--THSKPSESKAHH----RSRRFVSTPRYLEIMIVADQSMAEFHGA 222

  Fly   331 DLNGYLLTIMNMVSALYKDPSIGNSIEIVVVRIIQLDEEESQLQLNLTQNAQKNLDRFCSWQHKL 395
            .|..||||||.:.|.||:.|:|.|||.:.||:::.:.:||.  ..:::.||...|..||.||.:.
Zfish   223 QLKPYLLTIMAVASRLYRHPTIHNSITLAVVKLLVVHDEEH--GPHVSTNAALTLRSFCQWQKQH 285

  Fly   396 NKGSEKDPHHHDVAILITRKNIC-ANNCMTLGLANVGGMCKPKQSCSVNEDNGIMLSHTITHELG 459
            |:.|::.|.|:|.|:|.|||::| |::|.|||:|:||..|.|.:|||:.||:|:..:.|:.||||
Zfish   286 NQPSDRHPEHYDTAVLFTRKDLCGAHSCDTLGMADVGTACDPDRSCSIIEDDGLQAAFTVAHELG 350

  Fly   460 HNFGMFHDTAKIGCHPRVGPI--VHIMTPTFGADTLQVCWSNCSRKYITHFLDQGLGECLDDPPT 522
            |.|.|.||.|| .|....|..  .|:|..|.........||.||...:|.|||.|.|:||.|.|.
Zfish   351 HVFNMPHDDAK-QCASVNGDQWGAHMMASTLSNLNQLDPWSPCSALMVTSFLDNGHGQCLLDKPQ 414

  Fly   523 PLDEYNYTGELPGMRYNARGQCRLQFNLTTDSEVGACSAPHEFCSTLWCKV---NG--ECVTHMR 582
            ..:|...|  |||..|:|..||||.|.    .|...|......|:.|||.|   ||  .|.|...
Zfish   415 KPEELPQT--LPGSVYDADRQCRLTFG----EESQHCPDLSSTCAALWCTVTSANGLLVCQTKNF 473

  Fly   583 PTAPGTLCGRNKWCQNGKCVRREELA----AVNGGWGDWSEWSECSRSCGGGVSTQQRECDNPVP 643
            |.|.||.||.|.:|..|:|:.:.|.|    .||||||.|..|.:|||:|||||....|:|.||.|
Zfish   474 PWADGTPCGSNSYCMAGQCLSKTEAAKYETPVNGGWGSWGSWGDCSRTCGGGVQYSFRDCVNPRP 538

  Fly   644 ANGGVFCIGERKRYKICRKRPCP-AEEPSFRAQQCARFDNVSYQ-----GATYKWLPFFDKNNP- 701
            .|||.:|.|:|.:|:.|....|| :...:||.:||...:::|.|     |...:|:|.:...:|
Zfish   539 KNGGKYCEGKRIQYRSCNTETCPDSNGLTFREEQCLAHNDLSSQVSLGSGEGVEWVPKYAGVSPK 603

  Fly   702 --CKLFCSDVDDTIIANWGATVLDGTPCTLGTNNMCIDGICKKVGCDWIVDSEVQDDRCGVCGGS 764
              |||.|..............|.||||||..:.::|:.|.|.|.|||.::.|:.:.|:||:|||.
Zfish   604 DRCKLVCRAKGTGYFFILKPKVADGTPCTPDSTSVCVQGQCVKAGCDRVIGSDKRFDKCGICGGD 668

  Fly   765 GDQCQPVRETYTDPFAAKDGAYVEIVTIPARARHILIRELA-------NSPHFLAIATGDGGDRF 822
            |..|:.|..:..   .|:.| |.::|||||.|.|:.:::.:       ||  :||:...||.  :
Zfish   669 GSTCKKVSGSME---RARPG-YQDVVTIPAGATHLDVKQRSFGGRSQDNS--YLAVRRQDGS--Y 725

  Fly   823 YLNGD-SLISMPGEFEIAGA-----------ESLYDRVDEQETITI--------PQP-IQHSISL 866
            .|||| .|.::..:..:.||           |.|.......|.:||        |:| :::|
Zfish   726 LLNGDYKLTTLETDISVKGALLRYSGSSVLLERLRSFAPLPEPLTIQVLSVGESPRPRVKYS--- 787

  Fly   867 YAIVRGNESNAGIFYEFTLPALN-VTAGRQFQWRLSNWTACSASCGGGVQHREPICQENGK---- 926
            |...|.|.||.        |::| ::.....:|.|..|..||.:||||:|.|:.:|.::.:
Zfish   788 YFAPRPNGSNR--------PSINAISKAVDAEWFLGEWGTCSKTCGGGIQTRDVMCLDSKRRPSK 844

  Fly   927 --------------ALGDTLPCW------THAK----------------NKRPAR--------QS 947
                          ||.| .|.|      |.:|                |:||::        .|
Zfish   845 NCVDELRPASSRQCALQD-CPFWFLGEWGTCSKTCGGGIQTRDVMCLDHNRRPSKDCVELHPPSS 908

  Fly   948 RGCGDQPCPAHWWPGPWQFCPVTCRPVGFVAPPQRRRSVVCLDEHDVVVADAECGHLQKPAEMEP 1012
            |.|..|.||| |:.|.|..|..||.  |.:    ::|.|:|||.:.....|  |..| :||....
Zfish   909 RQCALQDCPA-WFLGEWGTCSKTCG--GGI----QKRDVMCLDHNHRPSED--CVEL-RPASSRQ 963

  Fly  1013 C 1013
            |
Zfish   964 C 964

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdamTS-B	NP_572247.2	Pep_M12B_propep	78..194	CDD:279848	32/120 (27%)
		ZnMc_ADAMTS_like	314..518	CDD:239801	89/207 (43%)
		Reprolysin	315..521	CDD:279729	91/209 (44%)
		ADAM_CR	<558..602	CDD:301627	19/48 (40%)
		TSP1	614..666	CDD:214559	25/51 (49%)
		ADAM_spacer1	773..886	CDD:283607	36/140 (26%)
		TSP1	901..956	CDD:214559	24/102 (24%)
adamts1	XP_021331598.1	Pep_M12B_propep	29..136	CDD:307618	30/105 (29%)
		ZnMc_ADAMTS_like	204..410	CDD:239801	90/208 (43%)
		ADAM_CR	423..495	CDD:326582	31/75 (41%)
		TSP1	517..561	CDD:214559	21/43 (49%)
		ADAM_spacer1	673..791	CDD:310520	33/128 (26%)
		TSP1	811..864	CDD:214559	15/53 (28%)
		TSP1	869..917	CDD:214559	9/47 (19%)
		TSP1	922..970	CDD:214559	17/52 (33%)
		TSP1	972..1026	CDD:214559

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D125522at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100241
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820