DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdamTS-B and wu:fb59d01

DIOPT Version :9

Sequence 1:	NP_572247.2	Gene:	AdamTS-B / 31490	FlyBaseID:	FBgn0029791	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	NP_001373281.1	Gene:	wu:fb59d01 / 322379	ZFINID:	ZDB-GENE-030131-1098	Length:	211	Species:	Danio rerio

Alignment Length:	167	Identity:	35/167 - (20%)
Similarity:	56/167 - (33%)	Gaps:	48/167 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 LANVGGMC----KPKQSCSVNEDNGIMLSHTITHELGHNFGMFHDTAKIGCHPRVGPIVHIMTPT 487
            ||.||..|    .|...|:..:|.|     |.|.::..   .|:|.....|.|      .....|
Zfish    10 LAVVGSGCVSASSPGPKCTGQKDEG-----TGTEKIKK---YFYDLQADSCVP------FYFKGT 60

  Fly   488 FG----ADTLQVCWSNCSRKYITHF-----------LDQGLGECLDDPPTPLDEYNYTGELPGM- 536
            .|    .|:.:.|...||.|.:..:           :|:|....|    .|:..||...::..|
Zfish    61 GGNGNRFDSDKECVKACSPKALQIYPTDETSICSMEMDEGTCFAL----FPMYYYNAEEKICRMF 121

  Fly   537 ----------RYNARGQCRLQFNLTTDSEVGACSAPH 563
                      |:.:|.:|:......:...:||...|:
Zfish   122 IYRGCRGNANRFESREECQQTCLARSGRLMGAADLPN 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdamTS-B	NP_572247.2	Pep_M12B_propep	78..194	CDD:279848
		ZnMc_ADAMTS_like	314..518	CDD:239801	24/109 (22%)
		Reprolysin	315..521	CDD:279729	25/112 (22%)
		ADAM_CR	<558..602	CDD:301627	2/6 (33%)
		TSP1	614..666	CDD:214559
		ADAM_spacer1	773..886	CDD:283607
		TSP1	901..956	CDD:214559
wu:fb59d01	NP_001373281.1	Kunitz_BPTI	27..77	CDD:394972	13/63 (21%)
wu:fb59d01	NP_001373281.1	Kunitz_BPTI	92..143	CDD:394972	10/54 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900