DRSC/TRiP Functional Genomics Resources

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Protein Alignment AdamTS-B and Adamtsl4

DIOPT Version :10

Sequence 1:NP_572247.2 Gene:AdamTS-B / 31490 FlyBaseID:FBgn0029791 Length:1023 Species:Drosophila melanogaster
Sequence 2:XP_038958286.1 Gene:Adamtsl4 / 310670 RGDID:1561012 Length:1035 Species:Rattus norvegicus


Alignment Length:538 Identity:147/538 - (27%)
Similarity:207/538 - (38%) Gaps:138/538 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   557 GACSAPHEFCSTLWCKVNGECVTHMRPTAPGTLCGRNKWCQNGKCVRREELAAVNGGW------- 614
            ||...||.|                .|.....| .|..|...|...|..:      ||       
  Rat   273 GAERQPHPF----------------SPVTRSQL-SRRHWRPPGSPHRSPD------GWLPLTRDS 314

  Fly   615 -GDWSEWSECSRSCGGGVSTQQRECDNPVPANGGVFCIGERKRYKICRKRPCPAEEPSFRAQQCA 678
             ..||.::..|                |.|.     |.||.::.:.|.:.|||.|:|..||.|||
  Rat   315 SPHWSLFAPSS----------------PTPE-----CSGESEQMRACSQEPCPPEQPDPRALQCA 358

  Fly   679 RFDNVSYQGATYKWLPFFD--KNNPCKLFCSDVDDTIIANWGATVLDGTPCTLGTNNMCIDGICK 741
            .||:..:.|..|:|.||.:  .:..|:|.|..............|.|||.|..|:.::|:.|.|.
  Rat   359 AFDSQEFMGQLYQWEPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGSLDICVAGHCL 423

  Fly   742 KVGCDWIVDSEVQDDRCGVCGGSGDQCQPVRETYTDPFAAKDG--AYVEIVTIPARARHILIREL 804
            ..|||.|:.|..:.|.||||||.|..|:.|....||    :.|  .|.:|:.|||.|.|:.|.:.
  Rat   424 SPGCDGILGSGRRPDGCGVCGGDGSTCRLVSGNLTD----RGGPLGYQKILWIPAGASHLRISQF 484

  Fly   805 ANSPHFLAIATGDGGDRFYLNGDSLISMPGEFEIAGAESLYDRVDEQ----ETITIPQPIQHSIS 865
            ..|.::||: .|.|| |..:||:..:..||.:...|....|:|...:    ||::...|....:.
  Rat   485 RPSSNYLAL-RGPGG-RSIINGNWAVDPPGSYAAVGTVFQYNRPPREEGKGETLSAEGPTTQPVD 547

  Fly   866 LYAIVRGNESNAGIFYEFTL-----------PALNV----------------------TAGRQFQ 897
            :|.|.:  |.|.|:||::..           |||.:                      |..||.:
  Rat   548 VYMIFQ--EDNPGVFYQYVTSAAPESPSTMPPALQLQPEMLRGEPLLPSAPRPVRAPGTLQRQAR 610

  Fly   898 --------------------WRLSNWTACSASCGGGVQHREPIC--QENGKALGDTLPCWTHAKN 940
                                |:....:.||||||.||.....:|  :|:|:.| |...|   |..
  Rat   611 IPQVPPPTHVRTAMGSSAGYWKQVGHSECSASCGKGVWRPIFLCVSRESGEEL-DEQSC---AVG 671

  Fly   941 KRPARQSRGCGDQPCPAHWWPGPWQFCPVTCRPVGFVAPPQRRRSVVCLDEH---DVVVADAECG 1002
            .||......|...|||.:|..|.|..|..:|      .|..:.|.::|..|.   ...|....||
  Rat   672 ARPPASPESCHRPPCPPYWEAGEWTSCSRSC------GPGTQHRQLLCRQEFGGGGSSVPPERCG 730

  Fly  1003 HLQKPAEMEPCESSLPIC 1020
            ||.:|...:.|:  |.:|
  Rat   731 HLPRPNITQSCQ--LRLC 746

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdamTS-BNP_572247.2 Pep_M12B_propep 47..195 CDD:460254
ZnMc_ADAMTS_like 314..518 CDD:239801
ADAMTS_CR_2 534..602 CDD:465496 10/44 (23%)
TSP1 614..666 CDD:214559 11/59 (19%)
ADAMTS_CR_3 672..768 CDD:437068 37/97 (38%)
ADAMTS_spacer1 770..886 CDD:461796 36/132 (27%)
TSP1 901..956 CDD:214559 19/56 (34%)
TSP1_ADAMTS 959..1020 CDD:465950 17/63 (27%)
Adamtsl4XP_038958286.1 PHA03247 <24..358 CDD:223021 30/128 (23%)
ADAMTS_CR_3 356..450 CDD:437068 35/93 (38%)
ADAMTS_spacer1 452..565 CDD:461796 36/120 (30%)
TSP1_ADAMTS 637..686 CDD:465950 18/52 (35%)
TSP1_ADAMTS 690..746 CDD:465950 17/63 (27%)
TSP1_ADAMTS 754..804 CDD:465950
TSP1_ADAMTS 808..869 CDD:465950
TSP1_ADAMTS 875..931 CDD:465950
TSP1_ADAMTS 935..986 CDD:465950
PLAC 994..1023 CDD:462560
Blue background indicates that the domain is not in the aligned region.

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