DRSC/TRiP Functional Genomics Resources

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Protein Alignment AdamTS-B and mig-17

DIOPT Version :10

Sequence 1:NP_572247.2 Gene:AdamTS-B / 31490 FlyBaseID:FBgn0029791 Length:1023 Species:Drosophila melanogaster
Sequence 2:NP_505901.2 Gene:mig-17 / 179575 WormBaseID:WBGene00003248 Length:509 Species:Caenorhabditis elegans


Alignment Length:338 Identity:87/338 - (25%)
Similarity:140/338 - (41%) Gaps:69/338 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   330 RDLNGYLLTIMNMVSALYKDPS-----IGNSIEIVVVRIIQLDEEESQ----LQLNLTQNAQKNL 385
            ||||...:.....:::...|.|     |.:.:...:.:.:.:..||.|    .::.|..:::|.:
 Worm   169 RDLNSTFVDDTFFMNSTDSDNSSTDALISSDMPKKLRKFVDITLEEMQENNSTEMTLKIDSKKAI 233

  Fly   386 DRFCSWQHKLNKGSEKDPHHHDVAILITRKNICA--NNCMTLGLANVGGMCKPKQSCSVNEDNGI 448
            |:|..|   |.:.:....|.|  |:|||:.::.:  .|..|.|:|.||.:|:...|.||.||.|.
 Worm   234 DKFTIW---LKEQTGLPRHEH--AVLITKFDLISINGNSATQGMAYVGNICENGDSSSVVEDIGA 293

  Fly   449 MLSHTI-THELGHNFGMFHD----TAKIGCHPRVGPIVHIMTPTFGADTLQVC----WSNCSRKY 504
            .|:..| .||:||:.|..||    ||:  |......::.:.. :..||.....    .||||...
 Worm   294 GLTSLIMAHEIGHSLGALHDGAYETAE--CDSNDNYLMAVAV-SGSADRQSFLNSRRMSNCSINS 355

  Fly   505 ITHFLDQGLGECLDDPPT----PLDEYNYTGELPGMRYNARGQCRLQFNLTTDSEVGACSAP--- 562
            |...|.:....|:....|    .:.:.::. :.||.......||::.|        |....|   
 Worm   356 IIENLKEPTANCVKKWKTKKGKDVSQKDFI-KKPGELVKITRQCQVAF--------GPTFIPCLH 411

  Fly   563 ----HE--FCSTLWCK--VNGECVT-HMRPTAPGTLCGRNKWCQNGKCVRREELAAVNGGWGDWS 618
                ||  .|..:||.  .:.||.| :..|...||.||.|.||..|.||:..:            
 Worm   412 IGYFHEQSICERIWCSDGESDECQTLNYFPAFDGTECGYNMWCLEGSCVQNTK------------ 464

  Fly   619 EWSEC----SRSC 627
            :|.:|    |::|
 Worm   465 KWMDCKDINSKTC 477

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdamTS-BNP_572247.2 Pep_M12B_propep 47..195 CDD:460254
ZnMc_ADAMTS_like 314..518 CDD:239801 56/207 (27%)
ADAMTS_CR_2 534..602 CDD:465496 24/79 (30%)
TSP1 614..666 CDD:214559 4/18 (22%)
ADAMTS_CR_3 672..768 CDD:437068
ADAMTS_spacer1 770..886 CDD:461796
TSP1 901..956 CDD:214559
TSP1_ADAMTS 959..1020 CDD:465950
mig-17NP_505901.2 ZnMc_ADAM_like 162..361 CDD:239795 54/199 (27%)
ADAMTS_CR_2 388..460 CDD:465496 24/79 (30%)
Blue background indicates that the domain is not in the aligned region.

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