Protein Alignment AdamTS-B and madd-4

DIOPT Version :9

• Sequence 1: NP_572247.2
• Gene: AdamTS-B / 31490
• FlyBaseID: FBgn0029791
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: NP_492405.3
• Gene: madd-4 / 172706
• WormBaseID: WBGene00009958
• Length: 1045
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 137/602 - (22%)
• Similarity: 184/602 - (30%)
• Gaps: 261/602 - (43%)

  Fly   614 WGDWSEWSECSRSCGGGVSTQQRECDNPVPANGGVFCIGERKRYKICRKRPCPAEEPSFRAQQCA 678
            |..||.||.|:::||||||.|.|.|....       |.||..|:|:|.::.|.::....|...|.
 Worm    26 WAAWSPWSSCTKTCGGGVSRQLRRCLTSK-------CSGESVRFKVCAQKTCESKSRLARDTICG 83

  Fly   679 RFDNVSYQGATYKWLPFFDKNNPCKLFCSDVDDTIIANWGATVLDGTPCTLGTNN-MCIDGICKK 742
            ..:.||              ...|::.|.  .....||:...|.|||||...|:. :|..|.|:.
 Worm    84 GEEIVS--------------RGQCEVVCR--SRLTGANFLWRVDDGTPCQAATSRAVCSKGSCQI 132

  Fly   743 VGCDWIVDSEVQDDRCGVCGGSGDQCQ------PVRETYT------DPFAAKDGA---------- 785
            ||||.::.|..:.|.||||||.||.|.      .|.|.||      |......||
 Worm   133 VGCDGLISSSFRFDACGVCGGRGDTCDNGKFIWKVSEEYTACASNCDDIVDWSGAGRSIASTSQP 197

  Fly   786 ----------------------------------------------------------------- 785
                                                                             
 Worm   198 IVVCVNAITGRVVPEKLCADKLRPKVEARPCPMLICPSRCRWMAADWTECVPHCGEGTRKREVYC 262

  Fly   786 --------------YVEIVTIPA-----------------------------RARHILI------ 801
                          :.|..|.||                             |.||:..
 Worm   263 VQTAHNVTVHVPDTFCENGTRPAAEENCVSTSCGRWEAGKWSKCTASCGQGVRRRHVACVGGSDC 327

  Fly   802 ------RE----LANSPHFLAIATGDGGDRFYLNGDSLISMPGEFE------IAGAES------- 843
                  |:    .|..|..:|..:.|..||.||:|::..||....:      :||..|
 Worm   328 DEGGRPRQETTCYAGIPCSIATNSLDWNDRAYLDGNTFGSMDNHNDWQAPRLVAGEWSTCSSTCG 392

  Fly   844 --LYDRVDE--------QETITIPQ--------------------PIQHSISLYAIVRGNESNAG 878
              :..|..|        ...|.:|.                    |:|....|      :|..|
 Worm   393 TGVMSRTVECVAVNPISSAPIKLPMSECQDQEQPKLFESCEVRSCPLQEDSKL------SEDEA- 450

  Fly   879 IFYEFTLPALNVTAGRQFQWRLSNWTACSASCGGGVQHREPICQE--NGKALGDTLPCWTHA-KN 940
                            .:|||..:||.|||||.||.|.....|.:  .||::.     |:.. ..
 Worm   451 ----------------PYQWRYGDWTQCSASCLGGKQKAALKCIQVSTGKSVQ-----WSQCDAR 494

  Fly   941 KRPARQSRGCGDQPCPAHWWPGPWQFCPVTCRPVGFVAPPQRRRSVVC---------LDEHDVVV 996
            :||..:||.|...|||..|....:..|.::|      .....||||.|         .|.| :|:
 Worm   495 RRPPEKSRPCNQHPCPPFWLTSKYSDCSMSC------GSGTARRSVKCAQTVSKTDGADAH-IVL 552

  Fly   997 ADAECGHLQKPAEMEPC 1013
            .|..| |.:||.|.|.|
 Worm   553 RDDRC-HFKKPQETETC 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdamTS-B	NP_572247.2	Pep_M12B_propep	78..194	CDD:279848
		ZnMc_ADAMTS_like	314..518	CDD:239801
		Reprolysin	315..521	CDD:279729
		ADAM_CR	<558..602	CDD:301627
		TSP1	614..666	CDD:214559	21/51 (41%)
		ADAM_spacer1	773..886	CDD:283607	37/295 (13%)
		TSP1	901..956	CDD:214559	20/57 (35%)
madd-4	NP_492405.3	TSP1	26..71	CDD:214559	21/51 (41%)
		TSP1	382..438	CDD:214559	6/55 (11%)
		IGc2	666..723	CDD:197706

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13723
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010