Protein Alignment AdamTS-B and adamts14

DIOPT Version :10

• Sequence 1: NP_572247.2
• Gene: AdamTS-B / 31490
• FlyBaseID: FBgn0029791
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: XP_031762102.1
• Gene: adamts14 / 100497380
• XenbaseID: XB-GENE-490125
• Length: 1240
• Species: Xenopus tropicalis
• Alignment Length: 1104
• Identity: 304/1104 - (27%)
• Similarity: 453/1104 - (41%)
• Gaps: 223/1104 - (20%)

  Fly    32 PLYGLHSDELVAG---EGQLVVPRRVHPDGAFMTHQLEYAHELDHRRHRQRRSLNSEHDTQ---- 89
            |:....:.|.::|   |..::||......|.:::|.:..|..       .|..|.|||..|
 Frog    21 PVESFTNKESISGKLSEYGVIVPFSTDHLGHYISHVVSAAGS-------SRGGLTSEHPGQTQRV 78

  Fly    90 ------AADLHLL--LPLANETLHLELMAHSYFLAPNLVVERHRRDLRTRSPLTTRHLNCHFHGK 146
                  :.|.||.  :.:..:.|||.|..:.:.::....|| .:.|.:..|. .:.|..|.:.|.
 Frog    79 ARSAPESYDRHLYFNVTVFGKQLHLRLKPNRHLVSHGATVE-WQEDFQETSQ-GSLHAGCVYTGD 141

  Fly   147 VRGQPATNVAISTCAGLVGHIRTAGNEYFIEP-SKEHEPHPVNGHPHVVFQRSSVKPKHSLRKRN 210
            :...|...||||.|.||.|.|||...|||||| .|..:....||..|||::||:|       ::|
 Frog   142 ITDMPGATVAISNCDGLAGMIRTDETEYFIEPLEKGRQDEEENGRAHVVYRRSAV-------QQN 199

  Fly   211 KRKRGGKSGSGAEVSNCGTREPRRRMETRLEWQARGKV--------KVQGGRQIRRHHHHHHHHH 267
            |                     ....||.....||.||        .:|.|   .|....:..|.
 Frog   200 K---------------------TANQETEHNEVARNKVGDLPYSLDLLQDG---LREKERNKRHA 240

  Fly   268 HKHKYRHHQQKISRVPHTKFKYETQFQTEPDHAEIPRRRRSISSPRHVETLIVADATMSAFH--R 330
            .|..|                                         ::|.|:..|.::..||  .
 Frog   241 KKDDY-----------------------------------------NIEVLLAVDDSVVRFHGKE 264

  Fly   331 DLNGYLLTIMNMVSALYKDPSIGNSIEIVVVRIIQLDEEESQLQLNLTQNAQKNLDRFCSWQHKL 395
            .:..|:||::|:|..:|.|.|:|..|.||:||:|.:...:| :.|....|..::||:.|.|.:..
 Frog   265 HVQNYVLTLLNIVDEIYHDESLGVHINIVLVRMIMVGYRQS-ISLIERGNPSRSLDQVCRWANSQ 328

  Fly   396 NKGSEKDPHHHDVAILITRKNICANNCMTLGLANVGGMCKPKQSCSVNEDNGIMLSHTITHELGH 460
            .:.......|||.|:.:||::.......  |.|.|.|||.|.:||::|.::|...:..:.||.||
 Frog   329 QRSDPDHAEHHDHAVFLTRQDFGPAGMQ--GYAPVTGMCHPLRSCTLNHEDGFSSAFVVAHETGH 391

  Fly   461 NFGMFHDTAKIGCHPRVGPIVHIMTPTFGADTLQVCWSNCSRKYITHFLDQGLGECLDDPPTPLD 525
            ..||.||.....|..... :..||.|...|...:..||.||::.:..::..  .:||.|.|.. .
 Frog   392 VLGMEHDGQGNRCADETS-MGSIMAPLVQAAFHRYHWSRCSKQELNRYIHS--YDCLLDDPFD-H 452

  Fly   526 EYNYTGELPGMRYNARGQCRLQFNLTTDSEVG--ACSAPHEF--CSTLWCKVNGE---CVTHMRP 583
            ::....||||:.|:...|||..|.      ||  .|:|...|  |..|||.....   |.|...|
 Frog   453 KWPKLPELPGINYSMDEQCRFDFG------VGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGP 511

  Fly   584 TAPGTLCGRNKWCQNGKCVRR--EELAAVNGGWGDWSEWSECSRSCGGGVSTQQRECDNPVPANG 646
            ...||.|...|||..|.|:.:  |:..:.:|||..||.:..|||:|||||.::.|:|:||.||.|
 Frog   512 PLDGTECSPGKWCFKGYCIWKTPEQSYSQDGGWSSWSRFGSCSRTCGGGVRSRSRQCNNPPPAYG 576

  Fly   647 GVFCIGERKRYKICRKRPCPAEEPSFRAQQCA-RFDNVSYQGATYKWLPF--FDKNNPCKLFC-- 706
            |..|.|....|::|....|......||||||: |....::|...:.|||:  .|....|:|.|
 Frog   577 GRDCPGAAYEYQMCNNEECRGPFEDFRAQQCSQRNSYYTHQNTKHMWLPYEHHDDAQKCELICQS 641

  Fly   707 SDVDDTIIANWGATVLDGTPCTL-GTNNMCIDGICKKVGCDWIVDSEVQDDRCGVCGGSGDQCQP 770
            .:..|.:..|  ..|.|||.|:. ...::|..|.|..:|||..:.|..:||:||||||....|:.
 Frog   642 KETGDVVFMN--QVVHDGTRCSYKDPYSVCARGDCVHIGCDKEIGSIKEDDKCGVCGGDNSHCRT 704

  Fly   771 VRETYTDPFAAKDGAYVEIVTIPARARHILIRELANSPHFLAIATGDGGDRFYLNGDSLISMPGE 835
            |:.|.... ..:....:::..|||.||||.|.|...|.:::||.....|:.. ||...:......
 Frog   705 VKGTLVKS-PKQTAGILKMFEIPAGARHIQIEETEPSTNYIAIKNQASGNPI-LNVKGVEGKSKT 767

  Fly   836 FEIAGAESLYDRVDEQETITIPQPIQHSISLYAIVRGNESNAGIFYEF-----TLPAL---NVTA 892
            |...|.:..|...|.:||:....|:...|.:..:.:..|....:.|::     .||.:   ||..
 Frog   768 FIELGLDWDYTIEDGKETVKTIGPLHEPIVVLVVPQEEEEKTTLTYKYIIHEDLLPMIGNNNVLL 832

  Fly   893 GR--QFQWRLSNWTACSASCGGGVQ---------------HR---------EPI--------CQE 923
            ..  .::|.|.:|:.||.:||||:|               ||         :||        |.:
 Frog   833 EEMDSYEWALKSWSQCSKACGGGIQYTKYGCRRKGDNRMVHRNFCDNNKKPKPIRRRCNQQECSQ 897

  Fly   924 NG----------KALGD------TLPCWTHAKN-------------KRPARQSRGCGDQPCPAHW 959
            .|          |:.|.      .:.|..|..|             :||..: |.|...||||.|
 Frog   898 PGWVAEEWGACSKSCGKLGVQARLVQCIQHLHNGTNRTVHTKYCTAERPETR-RPCNRTPCPAQW 961

  Fly   960 WPGPWQFCPVTCRPVGFVAPPQRRRSVVCLDEHDVVVADAECGHLQKPAEMEPCESSLPICRTK 1023
            ..|.|..|..:|      ....::|.|||....:.:   .:|.. :||..::.|.  :..|..|
 Frog   962 RTGAWSQCSSSC------GEGIQQRQVVCKASDNAI---GQCDG-EKPETIQVCR--MAACTGK 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdamTS-B	NP_572247.2	Pep_M12B_propep	47..195	CDD:460254	48/160 (30%)
		ZnMc_ADAMTS_like	314..518	CDD:239801	62/205 (30%)
		ADAMTS_CR_2	534..602	CDD:465496	26/74 (35%)
		TSP1	614..666	CDD:214559	23/51 (45%)
		ADAMTS_CR_3	672..768	CDD:437068	37/101 (37%)
		ADAMTS_spacer1	770..886	CDD:461796	27/120 (23%)
		TSP1	901..956	CDD:214559	24/115 (21%)
		TSP1_ADAMTS	959..1020	CDD:465950	13/60 (22%)
adamts14	XP_031762102.1	Pep_M12B_propep	76..191	CDD:460254	37/116 (32%)
		ZnMc_ADAMTS_like	245..446	CDD:239801	63/247 (26%)
		ADAMTS_CR_2	461..530	CDD:465496	26/74 (35%)
		TSP1	544..595	CDD:214559	23/50 (46%)
		ADAMTS_CR_3	601..702	CDD:437068	37/102 (36%)
		ADAMTS_spacer1	704..818	CDD:461796	27/115 (23%)
		TSP1_ADAMTS	840..895	CDD:465950	14/54 (26%)
		TSP1_ADAMTS	900..957	CDD:465950	9/57 (16%)
		TSP1_ADAMTS	961..1010	CDD:465950	13/60 (22%)