Protein Alignment AdamTS-B and adamts15

DIOPT Version :10

• Sequence 1: NP_572247.2
• Gene: AdamTS-B / 31490
• FlyBaseID: FBgn0029791
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: XP_012822382.1
• Gene: adamts15 / 100489270
• XenbaseID: XB-GENE-6051208
• Length: 938
• Species: Xenopus tropicalis
• Alignment Length: 1025
• Identity: 341/1025 - (33%)
• Similarity: 483/1025 - (47%)
• Gaps: 180/1025 - (17%)

  Fly    48 LVVPRRVHPDGAFMTHQLEYAHELDHRRHRQRRSLNSEHDTQAADLHLLLPLA--NETLHLELMA 110
            :|:|:|:.||             |:.|.:     |..|:| .|.||.::..:.  .|..:|.|:.
 Frog    30 VVIPKRLDPD-------------LNGRYY-----LKKEND-NAKDLGVIFQITAFYEDFYLNLIP 75

  Fly   111 HSYFLAPNL------VVERHRRDLRTRSPLTTRHLNCHFHGKVRGQPATNVAISTCAGLVGHIRT 169
            .:.|:||..      .:.:...|||          :|.:.|.|.....:..|:|.|.||.|....
 Frog    76 DAQFIAPAFSMHFPGSIPKQSPDLR----------HCFYSGDVNSDRDSFAALSLCGGLRGAFGY 130

  Fly   170 AGNEYFIEPSKEHEPHPVNGHPHVVFQRSSVKPKHSLRKRNKRKRGGKSGSGAEVSNCGTREPRR 234
            .|.||.|.|.:......:         :||.:..|.|::|.     |...|....|.||.
 Frog   131 QGEEYLIRPLQNVTRDQL---------QSSHQGPHLLQRRK-----GPLKSVDTTSRCGV----- 176

  Fly   235 RMETRLEWQARGKVKVQGGRQIRRHHHHHHHHHHKHKYRHHQQKISRVPHTKFKYETQFQTEPDH 299
                       |....||..:..          :|:|..|::::::   .|:.|        ..|
 Frog   177 -----------GSGLNQGIMEAL----------NKYKGSHNKKQLN---GTRLK--------GSH 209

  Fly   300 AEIPRRRRSISSPRHVETLIVADATMSAFH-RDLNGYLLTIMNMVSALYKDPSIGNSIEIVVVRI 363
                |.||..|..|:||||||||.||..|| .||..||||:|...:.||:.|||.|.|.||||:.
 Frog   210 ----RSRRFASITRYVETLIVADETMLKFHGDDLQHYLLTLMATAARLYRHPSIQNPINIVVVKF 270

  Fly   364 IQLDEEESQLQLNLTQNAQKNLDRFCSWQHKLNKGSEKDPHHHDVAILITRKNIC-ANNCMTLGL 427
            :.|.::....:  :|.||...|..||.||.|.||.|:|.|.:.|.|||.|:.::| |:.|.|||:
 Frog   271 MVLTDDGKGPK--VTTNAAMTLRSFCGWQKKWNKVSDKHPEYWDTAILFTKMDLCGASTCDTLGM 333

  Fly   428 ANVGGMCKPKQSCSVNEDNGIMLSHTITHELGHNFGMFHDTAKIGCHPRVGPI--VHIMTPTFGA 490
            |:||.||.||:||||.||:|:..:.|..|||||.|.|.||..|: |....|.:  .::|:||.
 Frog   334 ADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNMPHDNVKV-CEEAFGKLRENYMMSPTL-- 395

  Fly   491 DTLQV----CWSNCSRKYITHFLDQGLGEC-LDDPPTPLDEYNYTGELPGMRYNARGQCRLQFNL 550
              :|:    .||.||...||.|||.|.||| ||:|..|:   :...||||.||:...||.|.|.|
 Frog   396 --IQIDRANPWSACSAAIITDFLDSGHGECLLDEPAKPI---SLPEELPGARYSLSRQCELAFGL 455

  Fly   551 TTDSEVGACSAPH-EFCSTLWC--KVNGE--CVTHMRPTAPGTLCGRNKWCQNGKCVRREEL--A 608
                  |:...|: ::|:.|||  :..|:  |.|...|.|.||.||..|:|.||.||.|..:  .
 Frog   456 ------GSKPCPYMQYCTKLWCTGRARGQLVCQTRHFPWADGTSCGDGKFCLNGACVERHNVNRY 514

  Fly   609 AVNGGWGDWSEWSECSRSCGGGVSTQQRECDNPVPANGGVFCIGERKRYKICRKRPCPAEEPSFR 673
            .|:|.||.||.:.:|||:|||||...:|||:||.|:|||.||.|.|.:|:.|...|||....|||
 Frog   515 KVDGAWGKWSPYGQCSRTCGGGVQLAKRECNNPEPSNGGSFCEGLRVKYRSCSLNPCPETGKSFR 579

  Fly   674 AQQCARFDNVSYQ----GATYKWLPFFDKNNP---CKLFCSDVDDTIIANWGATVLDGTPCTLGT 731
            .:||..|:..::.    ..|..|:|.:...:|   |||.|..............|:|||||:...
 Frog   580 EEQCESFNGFNHSTNRITQTVGWVPKYSGVSPRDKCKLICRANGTGYFYVLSPKVVDGTPCSPDA 644

  Fly   732 NNMCIDGICKKVGCDWIVDSEVQDDRCGVCGGSGDQCQPVRETYTDPFAAKDGAYVEIVTIPARA 796
            .::|:.|.|.|.|||..:.|:.:.|:|.||||....|:.:...:|.|.    ..|..:|||||.|
 Frog   645 TSVCVQGKCIKAGCDGQLGSKKKYDKCRVCGGDNKSCKKISGLFTKPI----HGYNFVVTIPAGA 705

  Fly   797 RHILIRE-----LANSPHFLAIATGDGGDRFYLNGDSLISMPGEFEIAGAESL--YDRVDEQ-ET 853
            .::.:|:     |.|..::||:....|  |:.|||:.::: .||.:|:...||  |...... ||
 Frog   706 SNLDVRQRGYKGLINDDNYLAVKNAQG--RYLLNGNYIVA-AGERDISVRGSLLKYSGTGTAVET 767

  Fly   854 ITIPQPIQHSISLYAIVRGNESNAGIFYEFTLP-----------ALNVTAG---------RQFQW 898
            :.....||.|:::..:..|..:...:.|.|.:|           ..|..||         .|..|
 Frog   768 LQAINVIQESLTIEVLCVGKMTPPRLRYSFYIPREKKDGKVGQVISNSLAGLPPPLPRLKPQSNW 832

  Fly   899 RLSNWTACSASCGGGVQHREPICQENGKALGDTLPCWTHAKNKRPARQSRGCGDQPCPAHWWPGP 963
            ...||..||.|||.|.|.|...|::..:.|..  .|....   ||: :.|.||| |||. |..|.
 Frog   833 IAGNWGDCSVSCGTGHQIRTIECRDPWEQLAS--DCQAAL---RPS-ERRTCGD-PCPV-WDAGE 889

  Fly   964 WQFCPVTCRPVGFVAPPQRRRSVVCLDEHDVVVADAECGHLQKPAEMEPC 1013
            |..|..:|.. ||     :||.:.|..:..|.:....|...:||.|::.|
 Frog   890 WSSCSKSCGR-GF-----KRRQLRCSADGGVTLPREHCHLKRKPQELDFC 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdamTS-B	NP_572247.2	Pep_M12B_propep	47..195	CDD:460254	36/154 (23%)
		ZnMc_ADAMTS_like	314..518	CDD:239801	100/212 (47%)
		ADAMTS_CR_2	534..602	CDD:465496	28/72 (39%)
		TSP1	614..666	CDD:214559	28/51 (55%)
		ADAMTS_CR_3	672..768	CDD:437068	33/102 (32%)
		ADAMTS_spacer1	770..886	CDD:461796	33/123 (27%)
		TSP1	901..956	CDD:214559	20/54 (37%)
		TSP1_ADAMTS	959..1020	CDD:465950	16/55 (29%)
adamts15	XP_012822382.1	Pep_M12B_propep	30..158	CDD:460254	39/165 (24%)
		ZnMc_ADAMTS_like	219..425	CDD:239801	101/212 (48%)
		ADAMTS_CR_2	439..506	CDD:465496	28/72 (39%)
		TSP1	520..572	CDD:214559	28/51 (55%)
		ADAMTS_CR_3	<615..681	CDD:437068	24/65 (37%)
		ADAMTS_spacer1	683..800	CDD:461796	33/123 (27%)
		TSP1_ADAMTS	832..882	CDD:465950	20/56 (36%)
		TSP1_ADAMTS	885..938	CDD:465950	16/55 (29%)