DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdamTS-B and XB995277

DIOPT Version :9

Sequence 1:	NP_572247.2	Gene:	AdamTS-B / 31490	FlyBaseID:	FBgn0029791	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	XP_031760531.1	Gene:	XB995277 / 100487633	XenbaseID:	XB-GENE-995278	Length:	488	Species:	Xenopus tropicalis

Alignment Length:	363	Identity:	106/363 - (29%)
Similarity:	158/363 - (43%)	Gaps:	51/363 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   573 VNGECVTHMRPTAPGTLCGRNKWCQNGKCVRREELAAVNGGWGDWSEWSECSRSCGGGVSTQQRE 637
            ::.:|.|.:          .:...|:|...|..:     |.|..|:.|:..|.:||.||:.:.|.
Frog    17 IHADCDTQV----------TDSMYQSGGITRPSK-----GQWTAWASWTSSSSTCGNGVAVRTRR 66

  Fly   638 C------DNPVPANGGVFCIGERKRYKICRKRPCPAEEPSFRAQQCARFDNVSYQGAT--YKWLP 694
            |      |.         |.||:::|:.|:...||.:...||..|||.::.....|:.  |||:|
Frog    67 CLRVTRMDR---------CAGEQRQYRSCQSGICPEDALPFRDLQCALYNYRPIPGSQRGYKWVP 122

  Fly   695 FFDKNNPCKLFCSDVDDTIIANWGATVLDGTPCTLGTNNMCIDGICKKVGCDWIVDSEVQDDRCG 759
            |:.....|.|.|..|.......:| .|||||.|...:|..||:|.|.|..|:.|..|||..:.||
Frog   123 FYGAPTACHLNCLAVGQNFYYTFG-RVLDGTSCGPNSNGTCINGQCLKADCNGIFTSEVSKESCG 186

  Fly   760 VCGGSGDQCQPVRETYTDPFAAKD-GAYVEIVTIPARARHILIRELANSPHFLAIATGDGGDRFY 823
            .|....:.|..::..|..||.:.. ..|..:..|||.|..|.:.:  .|.:.||:...:|  .:.
Frog   187 KCQEQQNTCVLIQRVYLAPFPSSGYFGYKNVTRIPAGASQIKVMD--ESRNILALMDSNG--HYV 247

  Fly   824 LNGDSLISMPGEFEIAGAESLYDRVDE-QETITIPQPIQHSISLYAIVRGNESNAGIFYEFTLPA 887
            :|||.::|..|.:::||.|..|.|..| .|.:....|...  .||..|...|:|.||.|:|.||.
Frog   248 INGDWVVSWSGIYKVAGTEVHYIRNSESHEVLEADGPTNE--DLYVQVLFQENNPGITYQFWLPK 310

  Fly   888 ---LNVTAGRQFQWR------LSNWTACSASCGGGVQH 916
               .|........|:      |::|...:.| |.|..|
Frog   311 DLYDNYKREPHLSWQQSENEDLNSWVNKTTS-GNGESH 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdamTS-B	NP_572247.2	Pep_M12B_propep	78..194	CDD:279848
		ZnMc_ADAMTS_like	314..518	CDD:239801
		Reprolysin	315..521	CDD:279729
		ADAM_CR	<558..602	CDD:301627	4/28 (14%)
		TSP1	614..666	CDD:214559	16/57 (28%)
		ADAM_spacer1	773..886	CDD:283607	35/114 (31%)
		TSP1	901..956	CDD:214559	5/16 (31%)
XB995277	XP_031760531.1	TSP1	<56..92	CDD:214559	12/44 (27%)
		ADAM_CR_2	99..168	CDD:407643	25/69 (36%)
		ADAM_spacer1	207..309	CDD:368694	32/107 (30%)
		NTR	379..479	CDD:396359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000