Protein Alignment HMGB3 and Hmg-2

DIOPT Version :10

• Sequence 1: NP_001427702.1
• Gene: HMGB3 / 3149
• HGNCID: 5004
• Length: 222
• Species: Homo sapiens
• Sequence 2: NP_611553.1
• Gene: Hmg-2 / 37407
• FlyBaseID: FBgn0026582
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 209
• Identity: 50/209 - (23%)
• Similarity: 82/209 - (39%)
• Gaps: 68/209 - (32%)

Human    54 PEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMAKADKVRYDREMKDYGPAKGGKKKKDP------ 112
            ||.||:....|       ::|.......|||    ||           ||||.||.|:|
  Fly    13 PESPVSLPIAS-------QSMDTATIEDFDE----DK-----------PAKGKKKAKNPKGRHSD 55

Human   113 ------------------NAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDS 159
                              .|||.|.:|:..|.::.|.:::...|..:..:..:.:||.|:.|.:.
  Fly    56 SDIGSELKKLAQRRINVAGAPKMPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEE 120

Human   160 EKQPYITKAAKLKEKYEK---------------DVADYKSKGKFDGA------KGPAKVAR-KKV 202
            .|.|||..|||.|..|::               ::|..|...|.||:      ||.:.:.: ||.
  Fly   121 RKLPYIEAAAKDKAIYQEQLQMFLKEHPEIVANELAKAKKATKLDGSPKEKTPKGESALGKAKKT 185

Human   203 EEEDEEEEEEEEEE 216
            :.:..:.:.|:.::
  Fly   186 KAKPVKRQSEDPDD 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HMGB3	NP_001427702.1	None
Hmg-2	NP_611553.1	HMG-box_HMG20	75..154	CDD:438796	21/78 (27%)