Protein Alignment HMGB3 and Dsp1

DIOPT Version :10

• Sequence 1: NP_001427702.1
• Gene: HMGB3 / 3149
• HGNCID: 5004
• Length: 222
• Species: Homo sapiens
• Sequence 2: NP_001138203.1
• Gene: Dsp1 / 117294
• FlyBaseID: FBgn0278608
• Length: 397
• Species: Drosophila melanogaster
• Alignment Length: 214
• Identity: 96/214 - (44%)
• Similarity: 140/214 - (65%)
• Gaps: 21/214 - (9%)

Human    30 KPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMAKADKVRYD 94
            ||:|:|:|||:||||||||||||:|:..|.|||||:||:||||||..|||.:|.|||:.||.||:
  Fly   182 KPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYE 246

Human    95 REMKDYGPAKG-----GKKK---KDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGE 151
            .||::|.|.||     |||:   ||||||||..|.||.||::.|.|:|:.||...:||:||:||.
  Fly   247 AEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGR 311

Human   152 MWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKF-------------DGAKGPAKVARKKVE 203
            .|::::...||.|.:.|.:.|.:||:::.:||:.||.             ...|.....|..:.:
  Fly   312 KWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQQQ 376

Human   204 EEDEEEEEEEEEEEEEEDE 222
            .:..||:.::::.:.::||
  Fly   377 HQQLEEQHDDDDGDGDDDE 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HMGB3	NP_001427702.1	None
Dsp1	NP_001138203.1	HMG-box_HMGB_rpt1	182..250	CDD:438794	46/67 (69%)
		HMG-box_NHP6-like	262..342	CDD:438792	35/79 (44%)