Protein Alignment CG3149 and Rft1

DIOPT Version :10

• Sequence 1: NP_572246.1
• Gene: CG3149 / 31489
• FlyBaseID: FBgn0027564
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001412772.1
• Gene: Rft1 / 328370
• MGIID: 3607791
• Length: 562
• Species: Mus musculus
• Alignment Length: 574
• Identity: 206/574 - (35%)
• Similarity: 298/574 - (51%)
• Gaps: 66/574 - (11%)

  Fly     2 ARNVLESSLLGAGFSIIFQILCRILTFGINAYIVRHVGREVLGIMNV------------------ 48
            ::.||..:...|...::.|:|.|::||.:||:|:|.:.:|::||:||
Mouse     3 SQEVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVREPNGSSQTWDWQRSHLE 67

  Fly    49 ---RLLLLESTLLFLSREAINRAALSANAQQGDRCSWAQLINQMWLTVPICAVLCAPCL-YIWLN 109
               ||.||.||..||:|||..||.||..||:    .|:|.:|.:|||||: .:..:.|| ::||.
Mouse    68 LCTRLTLLYSTTTFLAREAFRRACLSGGAQR----DWSQTLNLLWLTVPL-GIFWSSCLGWVWLQ 127

  Fly   110 WLSAVDAIYASQYEFACYAVAFSCVLELMAESAVFVAQVFCFVKLKILLNTLHILVRSAIFLWIV 174
            .|...|......|.........|.|:||:.|....:||...|||||:|..::.:::||.:...:|
Mouse   128 LLEVPDPDVVPYYGTGVLFFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESMSVILRSVLTALLV 192

  Fly   175 TGDRSAAINAFAIAQLSSAVTIVLGQYGFFYFYLKGFKDFVTQQAKKKPVAPKAWQVSLYEHMDD 239
            .......:..|::|||.....:||    .:..||        .|..:.|.:.|  |::|
Mouse   193 LWLPHWGLYIFSLAQLLYTTVLVL----CYAIYL--------IQLLRSPESAK--QLTL------ 237

  Fly   240 FPFKQLSDFLPGVMFNPNGKHFNRELQTLTLSFVKQGVLKQILTEGEKYVMSVSPVLSFGEQATY 304
             |..:::..||.:  :.:....|.:...|..||.||..|||||||||:|||:...||:||:|..|
Mouse   238 -PVSRVTQLLPSI--SRSRAFVNWKEAGLAWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVY 299

  Fly   305 DVVNNLGSMAARFIFRPIEDSSYFYFTQTLSRDIKLAKQPQERVRQASSVLNNLLLGVSSIGLIA 369
            |:||||||:.||.||:|:|:|.|.:|.:.|.|:...:.|.|:.|..|::||.:||......||..
Mouse   300 DIVNNLGSLVARLIFQPVEESFYLFFAKVLEREKDASLQKQDDVAVAAAVLESLLKLALLTGLTM 364

  Fly   370 FTFGQSYSYPVLLLYGGPDFVAGGLPQSLLQWHCLAIYLLAVNGISEGYMFATNTSRDIDKYNYL 434
            ..||.:||...|.:|||....:|..| .|::.:||.:.|||:||::|.:|||..:..::|:||:.
Mouse   365 TVFGFAYSQLALDIYGGAMLSSGSGP-VLMRCYCLYVLLLAINGVTECFMFAAMSKEEVDRYNFT 428

  Fly   435 MAIFSVSFLVLSYILTGIFGPVGFIFANCINMLSRILYSTYYIRHQYRPLSLDPLLGL-WPGKLF 498
            |...|.|||||||:||...|.||||.|||.||..||..|..:|.|.:|.....||.|| ....|.
Mouse   429 MLALSSSFLVLSYLLTSWCGSVGFIMANCFNMGIRITQSLSFIHHYFRESPHRPLAGLRLSPVLL 493

  Fly   499 GCTLFLAGIV--------CYWYQSSDLATHLGV-----GVLAGLACLLSWALAH 539
            |..:..|||.        |.....:.|| |:.|     ||..|.|.|....|.|
Mouse   494 GVFILSAGITSVSEAFLCCERGWPARLA-HIAVGTICLGVTLGTAFLTETKLIH 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3149	NP_572246.1	Rft-1	8..547	CDD:427987	204/568 (36%)
Rft1	NP_001412772.1	None