Protein Alignment PGAP1 and BST1

DIOPT Version :10

• Sequence 1: NP_572245.1
• Gene: PGAP1 / 31487
• FlyBaseID: FBgn0029789
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: NP_116628.1
• Gene: BST1 / 850519
• SGDID: S000001869
• Length: 1029
• Species: Saccharomyces cerevisiae
• Alignment Length: 1133
• Identity: 227/1133 - (20%)
• Similarity: 409/1133 - (36%)
• Gaps: 320/1133 - (28%)

  Fly     2 FMFRNCAVLLVIGSIC-CFIYGLFRLHVEVEPNACRMTYMFGEPMFAKVGVRDGDQYP---NYAL 62
            :.:|..::|.:: ||| ..:..|.:.....:...|...|||  |.:|::...|....|   .|.|
Yeast    52 YTYRLFSILGIL-SICSLLLISLLKPFNGADAPQCESIYMF--PSYARIDGFDERYTPLAHKYHL 113

  Fly    63 YYYYEGL--RQPLDPLKRRMTGAPVIFVPGNAGSYKQVRSLASVA--------LRKAMSNDAGIH 117
            |.|.|..  |:||:..:.::.|.||:|:||||||::|.||:||..        .|..:.|:...:
Yeast   114 YLYREQSVDREPLNGDELQLDGIPVLFIPGNAGSFRQCRSIASACSNIYFDSNTRATLRNENVRN 178

  Fly   118 LDYYTIDYDEELSALYGGYLHRQQSYLKLCIRTILSIYEGRTEQP-----SIVLIGHSMGGKLAQ 177
            ||::|.|::|:.:|.:|..:..|..||...|:.|||:||...:.|     |::::||||||.:::
Yeast   179 LDFFTADFNEDFTAFHGETMLDQAEYLNDAIKYILSLYERTPDYPHPKPQSVIIVGHSMGGIVSR 243

  Fly   178 SVLVDPAIGQH----INTIISISTPLDQPVLNLDTQLEEFYDQTDAVLSKLRTATVPTMTTNVCD 238
            .:|   .:..|    |:||:::|:|.....:..|..:.:.|..|:....|
Yeast   244 VML---TLKNHVPGSISTILTLSSPHAASPVTFDGDILKLYKNTNEYWRK--------------- 290

  Fly   239 SLHQRPPSVQRMASQDSSARLDNVLLISTGGGNRDLLVRPGLTS-----SRFNDLHAMTSAIPKV 298
                       ..||:.|....|:.|:|..||..|..:.....|     |..|...:.|:.||.|
Yeast   291 -----------QLSQNDSFFSKNISLVSITGGILDTTLPADYASVEDLVSLENGFTSFTTTIPDV 344

  Fly   299 SLSCDHLSAVWCLQFMQAINRFLFSVAYVREDRSSIAFGTNKQRNLQTALSTF-------VKPRR 356
            ....|||:.|||.|..:.:.|.|.......:...........|...:..||.|       .|...
Yeast   345 WTPIDHLAIVWCKQLREVLARLLLESIDASKPEKVKPLNQRLQIARKLLLSGFEDYSWMNSKLNY 409

  Fly   357 RQQNTVRFGAAGNWHEERRLVINKYFTNGLKGTF-FDLIGLQR-QERYRKAAIEALNVD------ 413
            .|:|...|  :.|:..:       |.|..:.... |::..|:: ...|.|..|.: |:.
Yeast   410 PQENLQEF--SDNFFSD-------YATLEMNDVLDFEMFNLEKWHNNYTKINIPS-NISSTEHLH 464

  Fly   414 -------DEDWLFGCSAEDNNKTGQLYCEKATSLMHLV-------QWLPN----EDREPRSIALL 460
                   |...::.|:....|    |.|..|...:..|       |:..:    |.:.|.....:
Yeast   465 FTLLTSLDMPMIYFCTESRVN----LSCITAVDSILTVPRSSKDTQFAADSSFGEAKNPFKAVSV 525

  Fly   461 DLHNLRKTYVHWTHLLVRLPPSAKRIGYNLDIYDPKERVTD-----IKMPRWYTMAKLPLINET- 519
            ..:.|:|    :.:|::..|...:        :..:|.:.|     :.:.|  .::.:.::|.|
Yeast   526 GKNILQK----YDYLMISKPTYGE--------FSEQEGMEDNQGFLLALLR--NVSNVQIVNTTP 576

  Fly   520 -----------LQG-TLHHRVRISEMVDPYQSIRVIVEPLQCINPEYRVTARICVPWAAGFERFQ 572
                       |.| .:...:..|.:.|...|.::..: ::..|........:..|    |.|..
Yeast   577 SQILLFGEQLHLDGKDIEQVISFSNLWDSLLSYKLETK-IEASNEGIASEETLFQP----FIRQW 636

  Fly   573 TLKSFDQKPQLYV----------NVPTLVPRHYNTTLNPVTLEL--YLDPTCRYRISYEYSYSSA 625
            ..:.|:.|..|.:          ||...:|.:.:   .|.:|:|  ::.|..........::|..
Yeast   637 VYEPFESKWHLNIINKSLDINMHNVAPFIPLNES---EPRSLQLSFFIPPGMSLEAKMTINWSLT 698

  Fly   626 LSRLVLEFYGWLPAHLVCVLLIVLRKQVETFYDVGTFRSLRPYVGY-------LQYTSLYIVTAC 683
            |..|.:.:...|.:..|..:.:||..|...:.....|.|....:||       |.:.:|::.:..
Yeast   699 LKMLFIRYRLALASFPVAFIALVLSYQFYWYNKTSEFPSFDSTLGYILRKHGILMFFTLFLASPV 763

  Fly   684 RLLKKLIISSRVFPEPEPLDYSINVSIVIHCAAIALSLLATLGTWLALTLYGNAFYRLALRITRL 748
             :..||:.......:|..|:|...:|                    ...::.| ||.|.:|..
Yeast   764 -VNNKLVQRILYLLDPVGLNYPFLLS--------------------ERNMHAN-FYYLGIRDW-- 804

  Fly   749 SQATSNVMISIMTHLPITYGILTIATAMGTCSGVGLLLAFVFYFLMLSNAYKDYLEDFLWQKAAN 813
                      .|:.:.|.:|::|:        |:..|::.:|..|       :.|..||.:|.:.
Yeast   805 ----------FMSTIGILFGVMTV--------GLLALVSKIFGSL-------EILVIFLQRKLSK 844

  Fly   814 LVRGKPSAVTEQEDATEEQNEEQNALK-------------------------------------- 840
                |.:...|..|..|.:...:..|.
Yeast   845 ----KNTEDKEAFDTIEHKAYGKGRLMASVLLLLLVFFHIPYQMAFVISLVIQIATCIRVALLKL 905

  Fly   841 QNDEQKQQQQEEEEPEACVGLQNFSFHVTLLLMLFVQLLLNAP--------SSLAWLRSRR--HG 895
            .|:|||              |...::::||||:|.....:|.|        .::.|..|.|  |.
Yeast   906 SNNEQK--------------LNLLNYNMTLLLLLLFVSAINIPIIIVFLHNVAIKWETSFRSHHN 956

  Fly   896 INLPDPSLY----------PSIVVL----ASLSLLLQLRAPQKCQGYWMLSIAFYILAGVVLLYC 946
            |....|.::          |:.|.|    ..::::|           ::....|..:.|:..||.
Yeast   957 ILAVAPIIFLVGNNSIFKMPNSVPLDTWDGKVTIIL-----------FVYLTVFSFIYGIRNLYW 1010

  Fly   947 QAAIYRLTYVIAGAFALLSAHQSLWILW 974
               |:.|..:|..           |:|:
Yeast  1011 ---IHHLVNIICA-----------WLLF 1024

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGAP1	NP_572245.1	PGAP1	79..324	CDD:369540	77/266 (29%)
BST1	NP_116628.1	PGAP1	132..369	CDD:369540	77/265 (29%)