Protein Alignment PGAP1 and SPAC824.02

DIOPT Version :9

• Sequence 1: NP_572245.1
• Gene: PGAP1 / 31487
• FlyBaseID: FBgn0029789
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: NP_593441.1
• Gene: SPAC824.02 / 2542981
• PomBaseID: SPAC824.02
• Length: 1142
• Species: Schizosaccharomyces pombe
• Alignment Length: 1165
• Identity: 250/1165 - (21%)
• Similarity: 432/1165 - (37%)
• Gaps: 331/1165 - (28%)

  Fly     5 RNCAVLLVIGSICCFIYGLFRLHVEVEPNACRMTYMFGEPMFAKVGVRDGDQYP----NYALYYY 65
            |:.::.:.|.:|...:..|.......:.|.|..:|::  |.:.:. |...::|.    .|:||.|
pombe    80 RSWSLYVAIIAILLLLVILHSFQGRPQDNGCGKSYVW--PSYVRF-VDFDERYTRFANKYSLYLY 141

  Fly    66 YE-GLRQPLDPLKRRMTGAPVIFVPGNAGSYKQVRSLASVALR---KAMSNDAGIHL-------D 119
            .| .:.:..:|     :|.|::|:|||||||||||:.|:.|..   .|.:.||...|       |
pombe   142 REKSVEESDEP-----SGIPILFIPGNAGSYKQVRAFAAQAAHVYANAYAEDADGTLNAGKLVPD 201

  Fly   120 YYTIDYDEELSALYGGYLHRQQSYLKLCIRTILSIY------------EGRTEQPSIVLIGHSMG 172
            ::.:|::|:.||.:|..|..|..|:...|..|||:|            |......|::|:|||||
pombe   202 FFVVDFNEDFSAFHGQTLLDQAEYVNDAIPYILSLYRQNRKISSEYDNEAFPPPTSVILLGHSMG 266

  Fly   173 GKLAQSVL-----VDPAIGQHINTIISISTPLDQPVLNLDTQLEEFYDQTDAVLSKLRTATVPTM 232
            |.:||:..     ||.:    :||:|:::||.....|..|..|.|||:
pombe   267 GIVAQATFTMKNYVDGS----VNTLITLATPHAMAPLPFDRHLVEFYE----------------- 310

  Fly   233 TTNVCDSLHQRPPSVQRMASQD-----SSARLDNVLLISTGGGNRDLLVRPGLTS-SRF----ND 287
                         |::...||.     ....||:|||:|..||..|..|.|..:| |.|    |.
pombe   311 -------------SIKNFWSQSFLLSPEENSLDDVLLVSIAGGGLDTHVVPEYSSISTFVPPSNG 362

  Fly   288 LHAMTSAIPKVSLSCDHLSAVWCLQFMQAINRFLFSVAYVREDRSSIAFGTNKQ---------RN 343
            |...||.||.|....||.:..||..|.:.:.|.:|::...|..:.:::....|:         .:
pombe   363 LMVFTSGIPSVWAEIDHQAMAWCENFRRVLIRGIFAIMDARTSKCTVSLNLRKELLSRAYIQGSS 427

  Fly   344 LQTALSTFVKPRRRQQNTVRFGAAGNWHE--ERRLVINKYFTNGLKGTFFDL----IGLQRQERY 402
            .|..::...|| ..|...:.......:.|  .:.|.:|:...:.::...|.:    ..:.|.|..
pombe   428 FQNDITQISKP-IAQYKALDLDLTYVYSEMPGQLLFLNQLGVSYIRHHIFPIPKPTSSIDRFELL 491

  Fly   403 RKAAIE---------ALNVDD--EDWLFGCSAEDNNKTGQLYCEKATSLMHLVQWLPNEDREPRS 456
            ....|:         |..:|.  ::.:.......|||.....|.....|:.|:         |.|
pombe   492 TDQPIDLSSSNIKVLACRLDPKIDNTISALLENGNNKVINANCHLLRELVTLL---------PAS 547

  Fly   457 IALL-------DLHN--LRKTYVHWTHLLV-----RLPPSAKRIG--YNLDIYDPK----ERVTD 501
            .|..       ..:|  |.|..:...|.::     :.|.|...:|  .|:.: |||    .::..
pombe   548 TAYTSSPYGGDSFYNYVLPKEKMDDYHFILVSDDSKAPASGFVVGGFSNVSL-DPKTIKGSQIEL 611

  Fly   502 IKMPRWYTMAKLPLINETLQGTLHHRVR---ISEMVDPYQSIRVIVEPLQCINPEYRVTARICVP 563
            .|..|.:..        ..:|::..|.|   |...:..| :|.|..|......|:...|..:
pombe   612 FKSGRKFQF--------DTKGSISKRFRFPGIQSSIMAY-TISVTYELYPGAVPQKEFTPML--- 664

  Fly   564 WAAGFERFQTLKS-FDQKPQLYVNVPTLVPRHYNTTLN-----------------PVTLELYLDP 610
                   .|:::| |:.|  .:||:.       ||.|:                 .:|||.:|:|
pombe   665 -------KQSIESPFETK--YHVNMS-------NTELSVHGISPFMEFFGKESEKSLTLEFFLNP 713

  Fly   611 TCRYR---ISYEYSYSSALSRLVLEFYGWLPAHLVCVLLIVLRKQVETFYDVGTFRSLRPYVGYL 672
            .. |:   :|.:.||..:..||::.:...|.:..|.|:.:....|         ||       |.
pombe   714 AI-YKSVYVSIQPSYYRSAGRLLMRYRTLLASFPVVVISLAAYNQ---------FR-------YF 761

  Fly   673 QYTSLYIVTACRLLKKLIISSRVFPEPEPLDYSINVSIVIHCAAIALSLLAT------------L 725
            .|.|.|:..:..|  :::|...:          |.:..::...:||.|.|.:            :
pombe   762 HYGSAYLSMSAAL--EVMIRKGL----------IKLLFLVSILSIAFSYLISRVELIVADGADPV 814

  Fly   726 GTW----------------LALTLYGNAFYRLALRITRLSQA---TSNVMISIMTH-LPITYGIL 770
            .:|                |...|....|:.||..:|.:...   |::|:|..:.| |...|||.
pombe   815 ASWKIFAMMVPKSFWKQNHLLFGLQTAQFWFLAPLLTLMFVGLVITASVIILCVMHLLAFIYGIY 879

  Fly   771 TIATAMGTCSGVGLLLAFVFYFLMLSNAYK-DY-----LEDFLWQKAANLVRGKPS--------- 820
            .....: |.:||...:.|.|..|...|..| |:     |..||.|:  |:....||
pombe   880 LRYKGL-TFTGVCQAVKFSFQCLRTRNTRKLDHGEFKKLSSFLSQR--NMYYANPSLCYVYGKKH 941

  Fly   821 ---------------------------AVTEQEDATEEQNEEQNALKQNDEQKQQQQEEEEPEAC 858
                                       |:..|...|.:.........::...:::..:
pombe   942 MQARIIGIMLLLLMAMTVVPFQLVYGVALCTQTVTTAKALHLARFCTKSSHYRKKLWD------- 999

  Fly   859 VGLQNFSFHVTLLLMLFVQLLLNAPSSLAWLRSRRHGINLPDP------SLYPSIV---VLASLS 914
              ..|||..:|:|::|...  |:.|..:.|.|:.....::|.|      |:.|.|:   :|.:..
pombe  1000 --FYNFSCTITILMLLLAP--LDFPVLIVWARNLSMHWSIPFPTHHNFFSIIPFILLTEILRTGK 1060

  Fly   915 LLLQLRAPQKCQGYWMLSIAFYILAGVVLLYCQAAIYRLTYVIAGAFALLSAHQSLWILW 974
            :|.:|...:    |::.::..::|:...|:|.....|.:..|:...|        .|:|:
pombe  1061 MLPRLNDVE----YYINNVFLFLLSFYSLIYGAEKPYLIHNVVGLYF--------FWLLF 1108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGAP1	NP_572245.1	PGAP1	79..324	CDD:285110	89/281 (32%)
SPAC824.02	NP_593441.1	PGAP1	151..399	CDD:285110	90/286 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	112	1.000	Domainoid score	I1581
eggNOG	1	0.900	-	-		E1_KOG3724
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004158
OrthoInspector	1	1.000	-	-		oto101542
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15495
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R151
SonicParanoid	1	1.000	-	-		X2907
TreeFam	1	0.960	-	-
	9	8.990