| Sequence 1: | NP_572245.1 | Gene: | PGAP1 / 31487 | FlyBaseID: | FBgn0029789 | Length: | 980 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_034267.3 | Gene: | Epas1 / 13819 | MGIID: | 109169 | Length: | 874 | Species: | Mus musculus |
| Alignment Length: | 229 | Identity: | 47/229 - (20%) |
|---|---|---|---|
| Similarity: | 76/229 - (33%) | Gaps: | 69/229 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 131 ALYGGYL------------HRQQSYLKLCIRTILSIYEGR-----TEQPSIVLIGHSMGGKLAQS 178
Fly 179 VLVDPAIGQHINTIIS------------ISTPLDQPVLNLDTQLEEFYDQTDAV----------- 220
Fly 221 LSKLR-------TATVPTMTTNVCDSLHQRPPSVQRMAS-------QDSSARLDNVL-------L 264
Fly 265 ISTGGGNRDLLVRPGLTSSRFN--DLHAMTSAIP 296 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PGAP1 | NP_572245.1 | PGAP1 | 79..324 | CDD:285110 | 47/229 (21%) |
| Epas1 | NP_034267.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..23 | ||
| HLH | 12..68 | CDD:238036 | |||
| DNA-binding. /evidence=ECO:0000269|PubMed:26245371 | 26..53 | ||||
| PAS | 86..147 | CDD:214512 | |||
| Required for heterodimer formation with ARNT. /evidence=ECO:0000269|PubMed:26245371 | 171..192 | ||||
| PAS | 241..340 | CDD:238075 | 5/28 (18%) | ||
| PAS_3 | 254..341 | CDD:285623 | 6/29 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 438..489 | 10/50 (20%) | |||
| NTAD | 495..541 | 12/43 (28%) | |||
| HIF-1 | 516..548 | CDD:288296 | 6/18 (33%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 777..803 | ||||
| CTAD | 834..874 | ||||
| HIF-1a_CTAD | 837..873 | CDD:285931 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S163 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.950 | |||||