Protein Alignment PGAP1 and pgap1

DIOPT Version :10

• Sequence 1: NP_572245.1
• Gene: PGAP1 / 31487
• FlyBaseID: FBgn0029789
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: XP_031748645.1
• Gene: pgap1 / 100379938
• XenbaseID: XB-GENE-5818692
• Length: 929
• Species: Xenopus tropicalis
• Alignment Length: 1040
• Identity: 272/1040 - (26%)
• Similarity: 438/1040 - (42%)
• Gaps: 226/1040 - (21%)

  Fly     9 VLLVIG-SICCFIYGLFRLHVEVEPNACRMTYMFGEPMFAKVGV--RDGDQYPNYALYYYYEGLR 70
            |||.:| :...|.|         |.:.|.|||||..|.:.|:.:  :....||.|.||.|.|| .
 Frog    14 VLLALGVNDVFFAY---------ESSRCSMTYMFEYPEYQKIQLSKKVSRLYPLYELYLYGEG-S 68

  Fly    71 QPLDPLKRRMTGAPVIFVPGNAGSYKQVRSLASVALRKAMSNDAGIHLDYYTIDYDEELSALYGG 135
            ...:.....:||.||:|:|||||||||||||||||||||.:.....|.:.:|::::|||.|||||
 Frog    69 YAEENKNLTLTGVPVLFLPGNAGSYKQVRSLASVALRKAENIGNQYHFNIFTVNFNEELVALYGG 133

  Fly   136 YLHRQQSYLKLCIRTILSIYEGRTEQP-SIVLIGHSMGGKLAQSVLV----DPAIGQHINTIISI 195
            .|.||..::..||:|||.:|:.:...| |:.:|||||||.:|:::|.    .|.:   ||.||:.
 Frog   134 SLRRQTRFVHECIKTILCLYKNQKFPPESVAIIGHSMGGLIARALLTLNHFKPDL---INVIITQ 195

  Fly   196 STPLDQPVLNLDTQLEEFYDQTDAVLSKLRTATVPTMTTNVCDSLHQRPPSVQRMASQDSSARLD 260
            :||...|||:.||.|.:||                ||..|....               :|.:|.
 Frog   196 ATPHILPVLSADTYLTDFY----------------TMVNNYWIY---------------NSFKLR 229

  Fly   261 NVLLISTGGGNRDLLVRPGLT---SSRFND--LHAMTSAIPKVSLSCDHLSAVWCLQFMQAINRF 320
            |:..:|..||..|..||.|||   :|.|:.  |..::||:|:...|.||||.|||.:.:.|..|.
 Frog   230 NITTLSVAGGYSDYQVRSGLTFLPTSSFHTSALSVVSSAVPRTWASTDHLSIVWCRELVLATARA 294

  Fly   321 LFSVAYVREDRSSIAFGTNKQRNLQTALSTFVK-PRRRQQNTVRFGAAGNWHEERRLVINK---- 380
            ||.:.    |..:.....:.||.|......||: |.:..::..:..||  :.|..||:..|
 Frog   295 LFDLI----DGHTKQINRDPQRRLAVMKHHFVRHPAKHFESRHQITAA--FTETPRLITVKDSKW 353

  Fly   381 -YFTNGLKG-TFFDLIGLQRQERYRKAAIEALNVDDEDWLFGCSAEDNNKTGQLYCEKATSLMHL 443
             |..|.... :||....|.::..|.....:...:....|:|||     |||....|.:.|.|...
 Frog   354 TYTVNKESNESFFAFPLLDKRIVYSHFHCQNTFLYTHSWIFGC-----NKTVSPKCLQITDLSWE 413

  Fly   444 VQWLPNEDREPRSIALLDLHNLRKTYVHWTHLLVRLPPSAKRIGYNLDIYDPKERVTDIKMPRWY 508
            .:.||:     ..:..|.|    :.|.:.:|.::.| |:.....::::.....|..:.|.:|
 Frog   414 TELLPS-----AKVVTLKL----ELYSNLSHFILYL-PATNGSKFSVECEFLSEETSTIHVP--- 465

  Fly   509 TMAKLPLINETLQ---GTLHHRVRISEMV---------DPYQSIRV-IVEPLQCINPEYRVTARI 560
                   :...|.   .:.|.||..|.::         ..||:..| ||.....|........|.
 Frog   466 -------VTHVLSFGFSSSHARVNSSGLLYVIQFEDFSKIYQAFNVFIVRKCGQIKESKSSIYRF 523

  Fly   561 CVPWAAGFERFQTLKSFDQKPQLYVNVPTLVPRHYNTTLNPVTLELYLDPTCRYRISYEYSYSSA 625
            .|||:  .|....|.|.:...::...:....|.:.|..:|   |.||....|.:.::...|:...
 Frog   524 HVPWS--HEDVIGLLSDEFPVRIAAKLHAAQPHNDNRMVN---LFLYASQECLHEVTISTSFLQI 583

  Fly   626 LSRLVLEFYG-WLPAHLVCVLLIVLRKQVETF--------YDVGTFRSLRPYVGYLQYTSLYIVT 681
            |.::| .|:| :||.::|..||:....|:.:.        .||....:.:||    :...:.|:
 Frog   584 LGQIV-RFHGVYLPVYIVANLLLAYGAQLHSVLIQGSCMDLDVSLDVAAKPY----KVDPILII- 642

  Fly   682 ACRLLKKLIISSRVFPE---PEPLDYSINVSIVIHCAAIALSLLATLGTWLALT-----LYGNAF 738
             |:.|.......:.:.|   |: ||     ::.:|          |.|.|..|.     ::|.:.
 Frog   643 -CKYLLNYKWFKKAWDELMLPQ-LD-----AVQLH----------TFGFWFPLASLFFFIFGTSI 690

  Fly   739 -YRLALRITRLSQATSNVMISIMTHLPI-------TY----GILTIA-TAMGTCSGVGLLLAF-- 788
             |..::.:..:.:..|::.:...:..|:       ||    .||..| .:..:|....|||.|
 Frog   691 AYWSSVGLHSVLRIFSSLWMFFKSSPPVFPKESRFTYRVCVEILFFAFISWRSCGTFSLLLVFLR 755

  Fly   789 ------VFYFLMLSN-AYKDYLEDFLWQKAANLVRGKPSAVTEQEDATEEQNEEQNALKQNDEQK 846
                  :.|..:.|| :.|.::|....|.:.....|.....|:.:..........:.:|..|:
 Frog   756 YLSKVLILYSSVKSNISLKAHMEKLSKQNSVKTDSGTNKKSTQPDFNISHHQTPSSDIKSLDD-- 818

  Fly   847 QQQQEEEEPEACVGLQNFSFHVTLLLMLFVQLLLNAPSSLAWLRSRRHGINL-PDPSLYPSIVVL 910
                       |:     ..|.|:|.:....:||..||.:.||::.|:.|.| |||:..|::.::
 Frog   819 -----------CL-----KMHFTILNLNLWIVLLGLPSFVYWLKTLRYNIQLDPDPNRLPALALI 867

  Fly   911 ASLSLLLQ-----------------LRAPQKCQGYWMLSIAFYILAGVVLLYCQAAIYRLTYVIA 958
            ..|.:|:.                 |:.|        |||       :::.:....:||::|:||
 Frog   868 LILEILMNSSTSAIKSSVCLKTAAVLQLP--------LSI-------IIVAFGTLHLYRVSYLIA 917

  Fly   959  958
             Frog   918  917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGAP1	NP_572245.1	PGAP1	79..324	CDD:369540	104/254 (41%)
pgap1	XP_031748645.1	PGAP1	78..298	CDD:369540	104/253 (41%)