DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4119 and SNU71

DIOPT Version :9

Sequence 1:	NP_001284899.1	Gene:	CG4119 / 31481	FlyBaseID:	FBgn0028474	Length:	998	Species:	Drosophila melanogaster
Sequence 2:	NP_011527.1	Gene:	SNU71 / 852896	SGDID:	S000003245	Length:	620	Species:	Saccharomyces cerevisiae

Alignment Length:	549	Identity:	106/549 - (19%)
Similarity:	192/549 - (34%)	Gaps:	184/549 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 VSTFGFCEFDGPIAAMRAVRLLSEMEIDGKKLVAKVDAKNKVLIEDYKEQECKNGDRSNPVDEKT 157
            |:|..:|:     |....:|.|.|    ..|:...:|...|..:||      :.|...:...||.
Yeast   183 VNTLNYCK-----ALFAFIRKLHE----DFKIELHLDLNTKEYVED------RTGTIPSVKPEKA 232

  Fly   158 EDEFAIAQMHEFLEEHKHEFEGFDSSSRADLYGSANRNKKTRREEDIKMKV-LSENTLEE---EK 218
            .:.:::   .:.:|:...|                 ||.|..:.:|...:. :..|||.:   :.
Yeast   233 SEFYSV---FKNIEDQTDE-----------------RNSKKEQLDDSSTQYKVDTNTLSDLPSDA 277

  Fly   219 RNLISSEIGKFRMRAEEDEHRKELEKEKEKEKLAASKEKERKKQREMERMSSTSKSGSSSTAAAS 283
            .:.:..:|.:||.:.      ..:||||   |:.::.|:.|:::.:|:::....:...|
Yeast   278 LDQLCKDIIEFRTKV------VSIEKEK---KMKSTYEESRRQRHQMQKVFDQIRKNHS------ 327

  Fly   284 SSSATATSSTPAADGADMSDKTDKESVAVVIKETVKESKESASSTGRKESSSAAIEITQKERRSD 348
                          ||..|..|::|       :|..|.::....|    ....|:|..::||  |
Yeast   328 --------------GAKGSANTEEE-------DTNMEDEDEEDDT----EDDLALEKRKEER--D 365

  Fly   349 SKETRRR------RSKSRSKDRERERERELRELRDKERERERDRE---RERERERNEM---RERE 401
            .:|:.||      :..|.::.:.:....::....:.|...|::|.   :|.....|::   ..|.
Yeast   366 LEESNRRYEDMLHQLHSNTEPKIKSIRADIMSAENYEEHLEKNRSLYLKELLHLANDVHYDHHRS 430

  Fly   402 RNEMREREREREREREREEKLLKPVRDTWREKEMEDELRDRK-----------------KAEKKA 449
            ..|..||..|.:|.:....|.|.|:           :|.|.|                 |:|...
Yeast   431 FKEQEERRDEEDRAKNGNAKELAPI-----------QLSDGKAISAGKAAAITLPEGTVKSENYN 484

  Fly   450 REKEIAYQT----------RLTDWEVREKRKAKENEKYRLKELLRQEERETDAKRLKEFVEDYDD 504
            .:|.::..:          :..|..|   ..:.|:|.||..||...:..|..|
Yeast   485 ADKNVSESSEHVKIKFDFKKAIDHSV---ESSSEDEGYRESELPPTKPSERSA------------ 534

  Fly   505 ERDDSLYYRGRELQQRLAERVREADADSKDREKEAEELAELKSKFFSGEYENPSLEFEKARLEIE 569
             .:|.|.:...||..||...            ||:..:.||..:|. |.||:..:|:
Yeast   535 -AEDRLPFTADELNIRLTNL------------KESRYVDELVREFL-GVYEDELVEY-------- 577

  Fly   570 KLYEPRILINVNQEPPAAATSSVHQRKQA 598
                  ||.|:.          |:|.|||
Yeast   578 ------ILENIR----------VNQSKQA 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4119	NP_001284899.1	RRM_RBM25	62..136	CDD:240892	10/42 (24%)
CG4119	NP_001284899.1	PWI	917..988	CDD:214609
SNU71	NP_011527.1	PWI	547..620	CDD:214609	19/81 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900