Protein Alignment CG4119 and Rbm25

DIOPT Version :9

• Sequence 1: NP_001284899.1
• Gene: CG4119 / 31481
• FlyBaseID: FBgn0028474
• Length: 998
• Species: Drosophila melanogaster
• Sequence 2: NP_001351344.1
• Gene: Rbm25 / 67039
• MGIID: 1914289
• Length: 857
• Species: Mus musculus
• Alignment Length: 1068
• Identity: 354/1068 - (33%)
• Similarity: 497/1068 - (46%)
• Gaps: 305/1068 - (28%)

  Fly     1 MSYPPRAPMPPF----MNTAIPPPHIM---------QNMAKPPRSFRNSATISSQPTVYQ----- 47
            ||:||....||.    :...||||...         ..|...|.|....|.....|||..
Mouse    20 MSFPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTVSMVGKHL 84

  Fly    48 --RPPEPQPQFR------GPIITVFVGNISERVPEALLKRILNACGVVINWKRV-------STFG 97
              |...|..:.:      ||..|||||||||:..:.|::::|..||:|::||||       ..||
Mouse    85 GARKDHPGLKLKENDENCGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGASGKLQAFG 149

  Fly    98 FCEFDGPIAAMRAVRLLSEMEIDGKKLVAKVDAKNKVLIEDYKEQECKNG---------DRSNPV 153
            |||:..|.:.:||:|||.:::|..|||:.|||||.|..::::|.::..||         |....:
Mouse   150 FCEYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKANGNARPETVTNDDEEAL 214

  Fly   154 DEKTE--DEFAIAQMHEFLEEHKHEFEGFDSSSRADLYGSANRNKKTRREEDIKMK--------- 207
            ||:|:  |:.....:...:.|:..|...  .|..:|   |..|.||..::|||..:
Mouse   215 DEETKRRDQMIKGAIEVLIREYSSELNA--PSQESD---SHPRKKKKEKKEDIFRRFPVAPLIPY 274

  Fly   208 --VLSEN----TLEEEKRNLISSEIGKFR---MRAEEDEHRKELEKEK-EKEKLAASKEKERKKQ 262
              :..|:    .:||:||:|||.||.|||   .:.||::.:||.|::: |||:    :|:||:::
Mouse   275 PLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER----RERERERE 335

  Fly   263 REMERMSSTSKSGSSSTAAASSSSATATSSTPAADGADMSDKTDKESVAVVIKETVKESKESASS 327
            ||.||                                               :|..:|.:.....
Mouse   336 RERER-----------------------------------------------RERERERERERER 353

  Fly   328 TGRKESSSAAIEITQKERRSDSKETRRR-RSKSRSKDRERERERELRELRDKERERERDRERERE 391
            ...||..      .::||..|...|:.| |.:.|.:||:|||..:..:.|.:.||:.||||||||
Mouse   354 EKEKERE------RERERDRDRDRTKERDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 412

  Fly   392 RERNEMRERERNEMREREREREREREREEKLLKPVRDTWREKEM-EDELRDRKKAEKKAREKEIA 455
            |||...|||||...||||||||||||||       :|..|::|. |::..:|:|.|:|.||||.|
Mouse   413 RERERERERERERERERERERERERERE-------KDKKRDREEDEEDAYERRKLERKLREKEAA 470

  Fly   456 YQTRLTDWEVREKRKAKENEKYRLKELLRQEERETDAKRLKEFVEDYDDERDDSLYYRGRELQQR 520
            ||.||.:||:||::|.:|.||...:|..|:.|...:|||||||:|||||:|||..||||..||:|
Mouse   471 YQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKR 535

  Fly   521 LAERVREADADSKDREKEAEELAELKSKFFSGEYENPSLEFEKARLEIEKLYEPRILINVNQEPP 585
            |.:|.:|.:||.:||::|.|||.|::.:..:..:.:|..|.::...|.|:..:|:|    .|||.
Mouse   536 LRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQI----KQEPE 596

  Fly   586 AAATSSVHQRKQAASAPGEDDEGQKQRQKSQQLDSYDPDMAGTNDDDSISNDDRASMADTASNAS 650
            :.......|.|:.     :.:|..::.::.:|.....|.:.            ..|.|.:.|:||
Mouse   597 SEEEEEEKQEKEE-----KREEPVEEEEEPEQKPCLKPTLR------------PISSAPSVSSAS 644

  Fly   651 GVYAKNNNNDQSLSNSLSRHNSESRDSLAQIHTPTQSAILNDQESGHDAILPSATPPMTMPLISL 715
            |....|...|:|....:..|.:.......:.|.|...                         :||
Mouse   645 GNATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIG-------------------------LSL 684

  Fly   716 TLG--------NNLKKKKIEATGVFVNDDDNDENINPKKRKLVPLDYDDNISNTTPSNHAASSGS 772
            .||        |::|:||:....||...:|.|.:..|:|||||||||.::..|.|         .
Mouse   685 KLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLDYGEDDKNAT---------K 740

  Fly   773 GAANNSSSSNNNNSSSADRQSSAVSAATAAAAAVSQKIAQAFGGGSSGSGSGSGSGSNASGGKNN 837
            |..|.
Mouse   741 GTVNT------------------------------------------------------------ 745

  Fly   838 GGGSSSSSNNKHNSNSKHGKNEAAASAGSSADAAAANIKKDENGAKVYDEKRRHIKSIIDRIPTQ 902
                                                            :|||:||||:|::|||.
Mouse   746 ------------------------------------------------EEKRKHIKSLIEKIPTA 762

  Fly   903 KEELFNYKLDRNEIDSGLMERKIRPWINKKIIEYIGEPEPTLVDFICSKVLAGSPPQSILDDVQM 967
            |.|||.|.||.:.:||.||||:|||||||||||||||.|.|||||:||||:|.|.||||||||.|
Mouse   763 KPELFAYPLDWSIVDSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAM 827

  Fly   968 VLDEEAEVFVVKMWRLLIYELDAKKSGL 995
            |||||||||:||||||||||.:|||.||
Mouse   828 VLDEEAEVFIVKMWRLLIYETEAKKIGL 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4119	NP_001284899.1	RRM_RBM25	62..136	CDD:240892	39/80 (49%)
		PWI	917..988	CDD:214609	60/70 (86%)
Rbm25	NP_001351344.1	RRM_RBM25	106..188	CDD:409880	39/81 (48%)
		PWI	777..850	CDD:214609	61/72 (85%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836191
Domainoid	1	1.000	288	1.000	Domainoid score	I1568
eggNOG	1	0.900	-	-		E1_KOG2253
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	361	1.000	Inparanoid score	I2190
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59586
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003333
OrthoInspector	1	1.000	-	-		oto92183
orthoMCL	1	0.900	-	-		OOG6_103133
Panther	1	1.100	-	-	LDO	PTHR18806
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1872
SonicParanoid	1	1.000	-	-		X3224
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.880