Protein Alignment CG4119 and rbm25

DIOPT Version :9

• Sequence 1: NP_001284899.1
• Gene: CG4119 / 31481
• FlyBaseID: FBgn0028474
• Length: 998
• Species: Drosophila melanogaster
• Sequence 2: XP_031746171.1
• Gene: rbm25 / 407928
• XenbaseID: XB-GENE-490152
• Length: 810
• Species: Xenopus tropicalis
• Alignment Length: 1055
• Identity: 347/1055 - (32%)
• Similarity: 489/1055 - (46%)
• Gaps: 307/1055 - (29%)

  Fly     1 MSYPPRAPMPPF----MNTAIPPPHIM-------QNMAKPPRSFRNSATISSQPTVYQRPPEPQP 54
            |||||....||.    :...||||...       ..|...|.|..........|||........|
 Frog     1 MSYPPHLNRPPMGIPTLPPGIPPPQFPGFPPPPGTPMIPVPMSLMAPGPTVLVPTVSMVGKHLGP 65

  Fly    55 Q-------------FRGPIITVFVGNISERVPEALLKRILNACGVVINWKRV-------STFGFC 99
            :             ..||..|||||||||:..:.|::::|..||:|::||||       ..||||
 Frog    66 RKDMIGLKNKENDDNSGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGASGKLQAFGFC 130

  Fly   100 EFDGPIAAMRAVRLLSEMEIDGKKLVAKVDAKNKVLIEDYK-EQECKNG--------DRSNPVDE 155
            |:..|.:.:||:|||.:::|..|||:.|||||.|..::::| .:...||        |..:.|||
 Frog   131 EYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKASKRASNGSAKPESAADDEDDVDE 195

  Fly   156 KTE--DEFAIAQMHEFLEEHKHEFE--GFDSSSRADLYGSANRNKKTRREEDIKMKVLSEN---- 212
            .|:  |......:...::|:..|..  ..||.|.      ..:.||.::||......|.|:
 Frog   196 DTKRRDGIIKGAIEVLIKEYSSELNAPSQDSDSH------PRKKKKDKKEEMSNSVQLQEDINAI 254

  Fly   213 TLEEEKRNLISSEIGKFRMRAEEDEHRKELEKE---KEKEKLAASKE-KERKKQREMERMSSTSK 273
            .:||:||:|||.||.|||     |.|:| ||:|   ||||:....|| :||:::||.||
 Frog   255 EMEEDKRDLISREISKFR-----DTHKK-LEEEKGKKEKERQEIEKERRERERERERER------ 307

  Fly   274 SGSSSTAAASSSSATATSSTPAADGADMSDKTDKESVAVVIKETVKESKESASSTGRKESSSAAI 338
                                                     :|..:|
 Frog   308 -----------------------------------------RERERE------------------ 313

  Fly   339 EITQKERRSDSKETRRRRSKSRSKDRERERERELRELRDKERERERDRERERERERNEMRERERN 403
              .:|||   .||..|.|.:.|:|||:|:|:|:....|||:|:|.||..::|.|.|.:.|:|:|:
 Frog   314 --REKER---EKEKERERDRERNKDRDRDRDRDRDRDRDKDRDRARDHSKDRSRSREKSRDRDRD 373

  Fly   404 EMREREREREREREREEKLLKPVRDTWREK-----EMEDELRDRKKAEKKAREKEIAYQTRLTDW 463
            ..|||:|||||||:||       ||..::|     |.|:|..:|:|.|:|.||||.|||.||.:|
 Frog   374 RDRERDRERERERDRE-------RDREKDKKRDREEDEEEAYERRKLERKLREKEAAYQERLKNW 431

  Fly   464 EVREKRKAKENEKYRLKELLRQEERETDAKRLKEFVEDYDDERDDSLYYRGRELQQRLAERVREA 528
            |:||::||:|.||...:|..|:.|...:|||||||:|||||:|||..||||..||:||.:|.:|.
 Frog   432 EIRERKKAREYEKDAEREEERRRETAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEM 496

  Fly   529 DADSKDREKEAEELAELKSKFFSGEYENPSLEFEKARLEIEKLYEPRILINVNQEPPAAATSSVH 593
            :||.:||::|.|||.|::.:..:..:.:|..|.::...|.|:..:|.   .:..:|.:.....|.
 Frog   497 EADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEEERRRQPP---QIKPQPESEEEEEVK 558

  Fly   594 -QRKQAASAPGEDDEGQKQRQKSQQLDSYDPDMAGTNDDDSISNDDRASMADTASNAS--GVYAK 655
             .|::....|.|::|.:.:       ....|.|...:...|:|:..|.:..::..:.|  |:...
 Frog   559 PMREEKIEEPVEEEELEPK-------PCLKPTMRPISSAPSVSSGSRNATPNSPGDESPCGIIIP 616

  Fly   656 NNNNDQSLSNSLSRHNSESRDSLAQIHTPTQSAILNDQESGHDAILPSATPPMTMPLISLTLGNN 720
            :.|:.:.......|...|....|...::|:|               |:|.
 Frog   617 HENSPEQQPQEEYRPKIELSLKLGAPNSPSQ---------------PNAA--------------- 651

  Fly   721 LKKKKIEATGVFVNDDDNDENINPKKRKLVPLDYDDNISNTTPSNHAASSGSGAANNSSSSNNNN 785
             |:||:....||...||.|.:..|:|||||||||.|:                  :.:|:.||.|
 Frog   652 -KRKKLPVDSVFNKFDDEDSDEVPRKRKLVPLDYGDD------------------DKTSAKNNVN 697

  Fly   786 SSSADRQSSAVSAATAAAAAVSQKIAQAFGGGSSGSGSGSGSGSNASGGKNNGGGSSSSSNNKHN 850
            :
 Frog   698 T---------------------------------------------------------------- 698

  Fly   851 SNSKHGKNEAAASAGSSADAAAANIKKDENGAKVYDEKRRHIKSIIDRIPTQKEELFNYKLDRNE 915
                                               :|||:||||:|::|||.|.|||.|.||.:.
 Frog   699 -----------------------------------EEKRKHIKSLIEKIPTAKPELFAYPLDWSI 728

  Fly   916 IDSGLMERKIRPWINKKIIEYIGEPEPTLVDFICSKVLAGSPPQSILDDVQMVLDEEAEVFVVKM 980
            :|:.||||:|||||||||||||||.|.|||||:||||:|.|.||||||||.||||||||||:|||
 Frog   729 VDTTLMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKM 793

  Fly   981 WRLLIYELDAKKSGL 995
            |||||||.:|||.||
 Frog   794 WRLLIYETEAKKIGL 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4119	NP_001284899.1	RRM_RBM25	62..136	CDD:240892	39/80 (49%)
		PWI	917..988	CDD:214609	59/70 (84%)
rbm25	XP_031746171.1	RRM_RBM25	85..167	CDD:409880	39/81 (48%)
		PWI	730..803	CDD:214609	60/72 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	261	1.000	Domainoid score	I1920
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378934at33208
OrthoFinder	1	1.000	-	-		FOG0003333
OrthoInspector	1	1.000	-	-		otm47635
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1872
SonicParanoid	1	1.000	-	-		X3224
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090