Protein Alignment CG4119 and rbm25b

DIOPT Version :10

• Sequence 1: NP_572242.1
• Gene: CG4119 / 31481
• FlyBaseID: FBgn0028474
• Length: 998
• Species: Drosophila melanogaster
• Sequence 2: XP_009293281.1
• Gene: rbm25b / 327336
• ZFINID: ZDB-GENE-030131-5547
• Length: 830
• Species: Danio rerio
• Alignment Length: 1096
• Identity: 346/1096 - (31%)
• Similarity: 496/1096 - (45%)
• Gaps: 364/1096 - (33%)

  Fly     1 MSYPPRAPMP----PFMNTAIPPPHI-----------------MQNMAKPPRSFRNSATISSQPT 44
            ||:||....|    |.:...||||..                 |..||..|     :..:.:..:
Zfish     1 MSFPPHLNRPQIGIPTLPPGIPPPQFAGFPPTMPPGTPMIPVHMGIMAPAP-----AVLVPTTMS 60

  Fly    45 VYQRPPEPQPQ----------FRGPIITVFVGNISERVPEALLKRILNACGVVINWKRV------ 93
            |..:...|:.:          ..||..|||||||||:..:.|::::|..||:|::||||
Zfish    61 VVSKVAAPRKESIAAHAKDDDSSGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGASGK 125

  Fly    94 -STFGFCEFDGPIAAMRAVRLLSEMEIDGKKLVAKVDAKNKVLIEDYKEQE---CKNG------- 147
             ..|||||:..|.:.:||:|||.|:::..|||:.|||||.|..::::|.::   ..||
Zfish   126 LQAFGFCEYKEPESTLRALRLLHELQVGEKKLLVKVDAKTKAQLDEWKAKKKSTSANGNGKADDA 190

  Fly   148 --DRSNPVDEKTE--DEFAIAQMHEFLEEHKHEFEG---FDSSSRADLYGSANRNKKTRREEDIK 205
              :....:||:|:  |:.....:...:.|:..|...   .|.|||       .:.|:.:::||
Zfish   191 GEEEEEVLDEETKKRDQIVKGAIDGLIREYSSELNAQSQDDESSR-------RKKKREKKDED-- 246

  Fly   206 MKVLSENTLEEEKRNLISSEIGKFRMRAEEDEHRKELEKEK---EKEKLAASKE-KERKKQREME 266
              .::...:|::||:|||.||.|||     |.|:| ||:||   |||:....:| |||.|:||.|
Zfish   247 --DINAMEMEDDKRDLISREINKFR-----DTHKK-LEEEKGKREKERQELERERKERDKERERE 303

  Fly   267 RMSSTSKSGSSSTAAASSSSATATSSTPAADGADMSDKTDKESVAVVIKETVKESKESASSTGRK 331
            |
Zfish   304 R---------------------------------------------------------------- 304

  Fly   332 ESSSAAIEITQKERRSDSKETRRRRSKSRSKDRERERERELRELRDKERERERDRERERERERNE 396
                        |||...:|..|.|.:.|.::|||||:|: || |.|||:|:||.||:|.|:|:|
Zfish   305 ------------ERRDREREKERERERERERERERERDRD-RE-RTKERDRDRDWERDRSRDRSE 355

  Fly   397 MRERERNEMREREREREREREREEKLLKPVRDTWREKEMEDELRDRKKAEKKAREKEIAYQTRLT 461
            .|.|.|.:.|:|||:::::|:|||.              |:|..:|:|.|:|.||||.|||.||.
Zfish   356 GRSRSREQSRDRERDKDKKRDREED--------------EEEAYERRKLERKLREKEAAYQERLK 406

  Fly   462 DWEVREKRKAKENEKYRLKELLRQEERE----TDAKRLKEFVEDYDDERDDSLYYRGRELQQRLA 522
            :||:||::||::..    ||:.|:|||.    .:.||||||:|||||:|||..||||..||:||.
Zfish   407 NWELRERKKARDYS----KEIEREEERRREMAKEGKRLKEFLEDYDDDRDDPKYYRGSALQKRLR 467

  Fly   523 ERVREADADSKDREKEAEELAELKSKFFSGEYENPSLEFEKARLEIEKLYEPRILINVNQE---- 583
            :|.:|.:.|.:||::|.|||.|::.:..:..:.:|..|..:...|.|:|.:|.:.....:|
Zfish   468 DREKEIELDERDRKREKEELEEIRQRLLAEGHPDPDAELRRMEEEAERLRQPPVKPEPEEEREHK 532

  Fly   584 ------------------PPAAATSSVHQRKQA---ASAPGEDD--EGQKQRQKSQQLDSYDPDM 625
                              .|....:.||.....   |:.|.:||  ||::...:.:......|.|
Zfish   533 PSREERDRERGRDRDRRKAPVETHTHVHAHVHTHVHANIPSDDDVEEGEEIEDEEEPKPCLKPTM 597

  Fly   626 AGTNDDDSISNDDRASMADTASNASGVYAKNNNNDQSLSNSLSRHNSESRDSLAQIHTPTQSAIL 690
            .            ..:.|.:.|:|||....|...::|....:..|
Zfish   598 R------------PITAAPSVSSASGNATPNTPREESPCGIIIPH-------------------- 630

  Fly   691 NDQESGHDAILPSATPPMTMPLISLTLGNN--------LKKKKIEATGVFVNDDDNDENINPKKR 747
              :.|..:.:||....|...  :||.||::        .|:||:....||...||::.:..|:||
Zfish   631 --ENSPQEMLLPEENRPKIG--LSLKLGSSGSPGQPSVAKRKKLPVESVFNRFDDDEVDEAPRKR 691

  Fly   748 KLVPLDYDDNISNTTPSNHAASSGSGAANNSSSSNNNNSSSADRQSSAVSAATAAAAAVSQKIAQ 812
            |||||||:|                                   :..||..||.|
Zfish   692 KLVPLDYED-----------------------------------EEKAVDGATVA---------- 711

  Fly   813 AFGGGSSGSGSGSGSGSNASGGKNNGGGSSSSSNNKHNSNSKHGKNEAAASAGSSADAAAANIKK 877
                                |||                    |.|.
Zfish   712 --------------------GGK--------------------GVNT------------------ 718

  Fly   878 DENGAKVYDEKRRHIKSIIDRIPTQKEELFNYKLDRNEIDSGLMERKIRPWINKKIIEYIGEPEP 942
                    :|||:||||:|::|||.|.|||||.||.:.:|:.|||::|||||||||:|||||.|.
Zfish   719 --------EEKRKHIKSLIEKIPTAKPELFNYPLDWSVVDTALMEKRIRPWINKKIVEYIGEEEA 775

  Fly   943 TLVDFICSKVLAGSPPQSILDDVQMVLDEEAEVFVVKMWRLLIYELDAKKSGLAGK 998
            |||||:||||:|.|.||.|||||.||||||||||:||||||||||.:|||.|| ||
Zfish   776 TLVDFVCSKVMAHSTPQGILDDVAMVLDEEAEVFIVKMWRLLIYETEAKKIGL-GK 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4119	NP_572242.1	RRM_RBM25	62..136	CDD:409880	39/80 (49%)
		PWI	917..988	CDD:214609	56/70 (80%)
rbm25b	XP_009293281.1	RRM_RBM25	87..169	CDD:409880	39/81 (48%)
		PWI	750..823	CDD:214609	57/72 (79%)