Protein Alignment CG4119 and rbm-25

DIOPT Version :10

• Sequence 1: NP_572242.1
• Gene: CG4119 / 31481
• FlyBaseID: FBgn0028474
• Length: 998
• Species: Drosophila melanogaster
• Sequence 2: NP_001256427.1
• Gene: rbm-25 / 259655
• WormBaseID: WBGene00012245
• Length: 707
• Species: Caenorhabditis elegans
• Alignment Length: 1016
• Identity: 245/1016 - (24%)
• Similarity: 383/1016 - (37%)
• Gaps: 363/1016 - (35%)

  Fly    32 SFRNSATISSQPTVYQR----------------PPEPQPQFRGPIITVFVGNISERVPEALLKRI 80
            :||....:||.|...|:                |.:...|.:.....|||||||::..:..:::|
 Worm     2 AFRQGYGVSSYPHYPQQQQQIVFGQMRMPGQHTPAQQSSQQKPDSSPVFVGNISDKCSDEFIRKI 66

  Fly    81 LNACGVVINWKRV-------STFGFCEFDGPIAAMRAVRLLSEMEIDGKKLVAKVDAKNKVLIED 138
            ||.||.|.:|||:       ..||||.|......:||:|:|.|..:..|||..|
 Worm    67 LNECGNVASWKRIKGSNGKLQGFGFCHFTDLEGTLRALRILHEFHLGDKKLTVK----------- 120

  Fly   139 YKEQECKNGDRSNPVDEKTEDEFAIAQMHEFLEEHKHEFEGFDSSSRADLYGSANRNKKTRREED 203
                          .|||..|                           ||..:|..|:|.:.:::
 Worm   121 --------------PDEKVRD---------------------------DLRKNAIENRKRQGKKE 144

  Fly   204 IKMKVLSENTLEEEKRNLISSEIGKFRMRAEEDEHRKELEKEKEKEKLAASKEKERKKQREMERM 268
            :|:|       .:|             :.|:||:.:|:   |:.:.|:....|.:.|     |..
 Worm   145 LKLK-------HDE-------------LPADEDDLKKD---EEIRLKILHWMETDHK-----ELF 181

  Fly   269 SSTSKSGSSSTAAASSSSATATSSTPAADGADMSDKTDKESVAVVIK----ETVKESKESASSTG 329
            |.|.                        || ::||:|.|      :|    :..|::..|:||..
 Worm   182 SITE------------------------DG-ELSDETKK------VKGHDSKIEKQTVPSSSSNP 215

  Fly   330 RKESSSAAIEITQKERRSDSKETRRRRSKSRSKDRERERERELRELRDKERERERDRERERERER 394
            :|:               :.|..|.|||:||:    |.|||..|..|.||..|.: |.|......
 Worm   216 KKD---------------EHKRNRNRRSRSRT----RSRERTSRRSRSKESPRSK-RSRRSRSSS 260

  Fly   395 NEMRERERNEMR-----EREREREREREREEKLLKPVRDTWREKEMEDELRDRKKAEKKAREKEI 454
            |...|.:.:..|     .|.|.|..:|.|..|..   |......|..|:.|:::..::...:|:.
 Worm   261 NSSSESDSSSSRSSSYSSRSRSRTPQRSRTSKRR---RSNSHASEDSDDAREKRAFKQMMLDKKQ 322

  Fly   455 AYQTRLTDWEVREKRKAKENEKYRLKELLRQEERETDAKRLKEFVEDYDDERDDSLYYRGRELQQ 519
            ||..||..||.||::.:|..|:...||..|::..:.:.||||.|:||||||:||..||...:..|
 Worm   323 AYLARLKRWESRERQMSKRYEREERKEKDRKKTLQKEGKRLKLFLEDYDDEKDDPKYYTSSQFFQ 387

  Fly   520 RLAERVREADADSKDREKEAEELAELKSKFFSGEYENPSLEFEKARLEIEKLYEPRILINVNQEP 584
            |..:..||.:||.|||.:|.:|:.|||.:.......:.|:..|:   |..|.::.:.     ||.
 Worm   388 RKRDYEREREADQKDRMQEQQEIEELKRQIMEEAANDESINIEE---EARKRHKLKF-----QEE 444

  Fly   585 PAAATSSVHQRKQAASAP--------GEDDEGQKQRQKSQQLDSYDPDMAGTNDDDSISND---- 637
            .|       .||..|.:.        |:...|:|. ...::.||...|:. ....|.|..:
 Worm   445 EA-------MRKMRADSGSPNPHQPLGQSANGEKS-SSEEESDSEKTDVK-KEIKDEIKEEPIDV 500

  Fly   638 DRASMADTASNASGVYAKNNN-------NDQSLSNSLSRHNSESRDSLAQIHTPTQSAILNDQES 695
            |.:...|..:.:||.   |.|       :|.||:..::|..:....:..||.
 Worm   501 DISEHVDPNTGSSGT---NGNFGWKAIGDDSSLNTKINRPIANGNQNQPQIK------------- 549

  Fly   696 GHDAILPSATP-PMTMPLISLTLGNNLKKKKIEATGVFVNDDDNDENINPKKRKLVPLDYDDNIS 759
                  ..|:| |:...|                :|||.||||.|: ::.|| ||.|.:.
 Worm   550 ------KEASPIPIAQRL----------------SGVFGNDDDEDD-VHSKK-KLKPFEI----- 585

  Fly   760 NTTPSNHAASSGSGAANNSSSSNNNNSSSADRQSSAVSAATAAAAAVSQKIAQAFGGGSSGSGSG 824
                                        :.:.:...:||
 Worm   586 ----------------------------TREERMQVMSA-------------------------- 596

  Fly   825 SGSGSNASGGKNNGGGSSSSSNNKHNSNSKHGKNEAAASAGSSADAAAANIKKDENGAKVYDEKR 889
                                                                         :|||
 Worm   597 -------------------------------------------------------------EEKR 600

  Fly   890 RHIKSIIDRIPTQKEELFNYKLDRNEIDSGLMERKIRPWINKKIIEYIGEPEPTLVDFICSKVLA 954
            ...|.||..||..|:|||.::::.:::|...|..:||||:.||:.:::||.:.:..||||.::..
 Worm   601 ELTKQIIKTIPATKDELFVHRIEWDQLDGKWMNDRIRPWVAKKVTQFLGEEDKSFCDFICDQIEK 665

  Fly   955 GSPPQSILDDVQMVLDEEAEVFVVKMWRLLIYELDAKKSGL 995
            .:.||.||.||.:::||:||.||:|||||||||..|::.|:
 Worm   666 QATPQEILKDVAVIIDEDAEQFVIKMWRLLIYEGQARRLGI 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4119	NP_572242.1	RRM_RBM25	62..136	CDD:409880	30/80 (38%)
		PWI	917..988	CDD:214609	34/70 (49%)
rbm-25	NP_001256427.1	RRM_RBM25	49..129	CDD:409880	34/131 (26%)
		PTZ00121	<116..449	CDD:173412	119/481 (25%)
		PWI	628..701	CDD:214609	35/72 (49%)