Protein Alignment Sirt4 and HST2

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_015310.1
• Gene: HST2 / 856092
• SGDID: S000005936
• Length: 357
• Species: Saccharomyces cerevisiae
• Alignment Length: 284
• Identity: 77/284 - (27%)
• Similarity: 129/284 - (45%)
• Gaps: 65/284 - (22%)

  Fly    32 EDDIKRLEDFLLSKPN--VLVLTGAGISTESGIPDYRSEGVGLY---ARSN---HKPVQHMEFVK 88
            |..::::...:.|.||  |:.:.||||||..||||:||.|.|||   ||..   .:.|..::|.:
Yeast     9 EMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQ 73

  Fly    89 SS-----AVRKRYWARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAGSRN- 147
            |.     .:.|..:..||         :|:..|:.|..|:.::.::.|.|||:|.|..:||.::
Yeast    74 SDPLPFYTLAKELYPGNF---------RPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDD 129

  Fly   148 -VVEVHGSGYVVKCLSCEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLEYIENFRIPEC 211
             ::|.|||.....|:.|........|:|.||                   |.|   |::|  .:|
Yeast   130 LIIEAHGSFAHCHCIGCGKVYPPQVFKSKLA-------------------EHP---IKDF--VKC 170

  Fly   212 TQCGGDLKPEIVFFGDSVP--------------RPRVDQIAGMVYNSDGLLVLGSSLLV--FSGY 260
            ..||..:||.|||||:.:|              |.:: ..:|.......::|:|:||.|  |:..
Yeast   171 DVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKI-TTSGKHPQQPLVIVVGTSLAVYPFASL 234

  Fly   261 RVVLQTKDLKLPVGIVNIGETRAD 284
            ...:..|..::...:..:|:.:|:
Yeast   235 PEEIPRKVKRVLCNLETVGDFKAN 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	76/278 (27%)
HST2	NP_015310.1	SIRT1	26..277	CDD:238699	73/267 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810