Protein Alignment Sirt4 and HST3

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_014668.1
• Gene: HST3 / 854190
• SGDID: S000005551
• Length: 447
• Species: Saccharomyces cerevisiae
• Alignment Length: 371
• Identity: 91/371 - (24%)
• Similarity: 145/371 - (39%)
• Gaps: 111/371 - (29%)

  Fly    10 RSTSLRS---STARQEYVPHHKPVVEDD--IKRLEDFLLSKPNVLVLTGAGISTESGIPDYRSEG 69
            ||.|:.|   |:.:.|.:.|...:..||  ::|:...|.....:..|||||||..:||||:||..
Yeast    12 RSGSMCSDLPSSLQTEKLAHIIGLDADDEVLRRVTKQLSRSRRIACLTGAGISCNAGIPDFRSSD 76

  Fly    70 VGLYARSNHKPVQHMEFVKSSAVRKRYWA----RNFVG------------WPKF--------SAT 110
             |||           :.||...  .:||:    |....            :.||        ...
Yeast    77 -GLY-----------DLVKKDC--SQYWSIKSGREMFDISLFRDDFKISIFAKFMERLYSNVQLA 127

  Fly   111 QPNATHHALARFEREERVQAVVTQNVDRLHTKAG------------------SRNVVEVHGSGYV 157
            :|..||..:|..:...::....|||:|.|....|                  :.:||::||....
Yeast   128 KPTKTHKFIAHLKDRNKLLRCYTQNIDGLEESIGLTLSNRKLPLTSFSSHWKNLDVVQLHGDLKT 192

  Fly   158 VKCLSCEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPL----EYIENFRIPECTQCGGD- 217
            :.|..|        ||:.     |..:.....:|..   |:||    |.:.|.|:.|..:..|.
Yeast   193 LSCTKC--------FQTF-----PWSRYWSRCLRRG---ELPLCPDCEALINKRLNEGKRTLGSN 241

  Fly   218 ---LKPEIVFFGDSVPRPRV-------DQIAGMVYNSDGLLVLGSSLLVFSGYRVVLQTKDLKLP 272
               |:|.||.:|::.|...:       |.|.|   |.|.|:::|:||.| .|.:.:::....|:.
Yeast   242 VGILRPNIVLYGENHPSCEIITQGLNLDIIKG---NPDFLIIMGTSLKV-DGVKQLVKKLSKKIH 302

  Fly   273 -----VGIVN---IGETRADHLADIKISAKCGD-------VIPKLF 303
                 :.:||   |||:....:.|.:|.:.|.:       .||..|
Yeast   303 DRGGLIILVNKTPIGESSWHGIIDYQIHSDCDNWVTFLESQIPDFF 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	78/332 (23%)
HST3	NP_014668.1	SIR2	42..349	CDD:223915	82/341 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810