Protein Alignment Sirt4 and HST4

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_010477.3
• Gene: HST4 / 851772
• SGDID: S000002599
• Length: 370
• Species: Saccharomyces cerevisiae
• Alignment Length: 353
• Identity: 84/353 - (23%)
• Similarity: 129/353 - (36%)
• Gaps: 106/353 - (30%)

  Fly     5 QLLRFRSTSLRSSTARQEYVP----------------------HHKPVVEDDIKRLEDFLLSKPN 47
            :||.....|:|:...|..|.|                      ||   ::.|...:...|.....
Yeast    33 RLLPQLKKSVRNRKPRLSYRPELNSVFDLDAYVDSTHLSKSQRHH---MDRDAGFISYALNYSKR 94

  Fly    48 VLVLTGAGISTESGIPDYRSEGVGLYARSN---HKPVQHMEFVKSSAVRKRYWARNFVGWPKFSA 109
            ::|::|||||..:||||:|| ..|:::..|   .|.:.....|.........:.:..|...:.|.
Yeast    95 MVVVSGAGISVAAGIPDFRS-SEGIFSTVNGGSGKDLFDYNRVYGDESMSLKFNQLMVSLFRLSK 158

  Fly   110 T-QPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNV---------VEVHGSGYVVKCLS 162
            . ||...|..|..|.|:.|:..:.|||:|.|.|:..  |.||         |::|||   :|.:.
Yeast   159 NCQPTKFHEMLNEFARDGRLLRLYTQNIDGLDTQLPHLSTNVPLAKPIPSTVQLHGS---IKHME 220

  Fly   163 CEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLEYIENFRIPECTQCG------------ 215
            |...::...|...|...:..|         |...||         ||.|.||.
Yeast   221 CNKCLNIKPFDPELFKCDDKF---------DSRTEI---------IPSCPQCEEYETVRKMAGLR 267

  Fly   216 ----GDLKPEIVFFGDSVPRPRVDQIAGMVYNS-----DGLLVLGSSLLVFSGYRVVLQTKDLKL 271
                |.|:|.::.:.:  ..|..|.|..:..|.     |.|:::|:|               ||:
Yeast   268 STGVGKLRPRVILYNE--VHPEGDFIGEIANNDLKKRIDCLIIVGTS---------------LKI 315

  Fly   272 PVGIVNIGETRADHLADIKISAKCGDVI 299
            | |:.||....|     .|:.|..|.|:
Yeast   316 P-GVKNICRQFA-----AKVHANRGIVL 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	73/296 (25%)
HST4	NP_010477.3	SIR2	77..370	CDD:223915	76/309 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810