Protein Alignment Sirt4 and sirt1

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: XP_001334440.4
• Gene: sirt1 / 797132
• ZFINID: ZDB-GENE-070801-2
• Length: 710
• Species: Danio rerio
• Alignment Length: 311
• Identity: 89/311 - (28%)
• Similarity: 138/311 - (44%)
• Gaps: 73/311 - (23%)

  Fly    34 DIKRLED---FLLSKPNVLVLTGAGISTESGIPDYRSEGVGLYARSNHKPVQHMEFVKSSAVRK- 94
            ||..|||   .|..:..:|||||||:|...||||:||.. |:|||   ..|...:.....|:..
Zfish   175 DINTLEDVVRLLNERKKILVLTGAGVSVSCGIPDFRSRD-GIYAR---LAVDFPDLPDPQAMFDI 235

  Fly    95 RYWARNFVGWPKFSAT------QPNATHHALARFEREERVQAVVTQNVDRLHTKAGSRNVVEVHG 153
            .|:.|:...:.||:..      ||:..|..::..:::.|:....|||:|.|...||.:.:::.||
Zfish   236 DYFRRDPRPFFKFAKEIYPGQFQPSPCHRFISMLDKKGRLLRNYTQNIDTLEQVAGIQKIIQCHG 300

  Fly   154 SGYVVKCLSCEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLEYIENFRIPECTQCGGD- 217
            |.....||.|::::|                  .:.||.|         |.|..:|.|.:|..|
Zfish   301 SFATASCLICKHKVD------------------CEAIRED---------IFNQVVPHCPRCPSDV 338

  Fly   218 ----LKPEIVFFGDSVP-------RPRVDQIAGMVYNSDGLLVLGSSLLVFSGYRVVLQTKDLKL 271
                :||:|||||:::|       :...|::       |.|:|:||||.|   ..|.|....:..
Zfish   339 PYAIMKPDIVFFGENLPEFFHRAMKQDKDEV-------DLLIVIGSSLKV---RPVALIPSSIPH 393

  Fly   272 PVGIVNIGETRADHL-ADIKISAKCGDVIPKLF-----DFR----NSKSVS 312
            .|..|.|......|| .|:::...|..::.:|.     ||:    ||..:|
Zfish   394 DVPQVLINREPLPHLNFDVELLGDCDVIVNELCHRLNGDFQQLCYNSSRLS 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	81/283 (29%)
sirt1	XP_001334440.4	SIRT1	190..425	CDD:238699	77/275 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810