Protein Alignment Sirt4 and Sirt4

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: XP_036021467.1
• Gene: Sirt4 / 75387
• MGIID: 1922637
• Length: 393
• Species: Mus musculus
• Alignment Length: 323
• Identity: 147/323 - (45%)
• Similarity: 207/323 - (64%)
• Gaps: 20/323 - (6%)

  Fly     7 LRFRSTSLRSSTARQE---------YVPHHKPVVEDDIKRLEDFLLSKPNVLVLTGAGISTESGI 62
            |.||.|..|..|....         :||...|:..:.||.|:.|:.....:||:|||||||||||
Mouse    45 LTFRPTKGRWITHLSRPRSCGPSGLFVPPSPPLDPEKIKELQRFISLSKKLLVMTGAGISTESGI 109

  Fly    63 PDYRSEGVGLYARSNHKPVQHMEFVKSSAVRKRYWARNFVGWPKFSATQPNATHHALARFEREER 127
            ||||||.||||||::.:|:||::||:|:.||:|||||||||||:||:.|||..|.||:.:||..:
Mouse   110 PDYRSEKVGLYARTDRRPIQHIDFVRSAPVRQRYWARNFVGWPQFSSHQPNPAHWALSNWERLGK 174

  Fly   128 VQAVVTQNVDRLHTKAGSRNVVEVHGSGYVVKCLSCEYRIDRHEFQSILASLNPAFKDAPDMIRP 192
            :..:||||||.||:||||:.:.|:||..:.|.||:|..:..|...|....:|||::......:.|
Mouse   175 LHWLVTQNVDALHSKAGSQRLTELHGCMHRVLCLNCGEQTARRVLQERFQALNPSWSAEAQGVAP 239

  Fly   193 DGDVEIPLEYIENFRIPECTQCGGDLKPEIVFFGDSVPRPRVDQIAGMVYNSDGLLVLGSSLLVF 257
            ||||.:..|.:.:|::|.|.:|||.|||::|||||:|...:||.:...|..:|.|||:||||.|.
Mouse   240 DGDVFLTEEQVRSFQVPCCDRCGGPLKPDVVFFGDTVNPDKVDFVHRRVKEADSLLVVGSSLQVP 304

  Fly   258 SGYRV----------VLQTKDLKLPVGIVNIGETRADHLADIKISAKCGDVIPKLFDFRNSKS 310
            ...||          :|..::.|||:.|:|||.||:|.||.:|:.::||:::| |.|.|...|
Mouse   305 DSVRVAVAFAHPTGFILTAREQKLPIAILNIGPTRSDDLACLKLDSRCGELLP-LIDPRRQHS 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	131/270 (49%)
Sirt4	XP_036021467.1	SIRT4	85..356	CDD:238700	134/274 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841844
Domainoid	1	1.000	226	1.000	Domainoid score	I2506
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8164
Inparanoid	1	1.050	294	1.000	Inparanoid score	I2729
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56570
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005863
OrthoInspector	1	1.000	-	-		oto91884
orthoMCL	1	0.900	-	-		OOG6_103918
Panther	1	1.100	-	-	LDO	PTHR48252
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2794
SonicParanoid	1	1.000	-	-		X4258
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790