Protein Alignment Sirt4 and sirt5

DIOPT Version :10

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_001002605.1
• Gene: sirt5 / 436878
• ZFINID: ZDB-GENE-040718-349
• Length: 305
• Species: Danio rerio
• Alignment Length: 289
• Identity: 81/289 - (28%)
• Similarity: 137/289 - (47%)
• Gaps: 29/289 - (10%)

  Fly    34 DIKRLEDFLLSKPNVLVLTGAGISTESGIPDYRSEGVGLYARSNHKPVQHME-FVKS-SAVRKRY 96
            |:....:......::.::||||:|.|||:|.:|..| |.:.:...:.:...| |.:. |.|.:.|
Zfish    35 DLTAFREHFAKAKHIAIITGAGVSAESGVPTFRGPG-GFWRKWQAQDLATPEAFSRDPSLVWEFY 98

  Fly    97 WARNFVGWPKFSATQPNATHHAL----ARFEREERVQAVVTQNVDRLHTKAGSRNVVEVHGSGYV 157
            ..|..|    ..:..||..|.|:    ||..::.|...::|||:|.||.:|||::|.|:|||.:.
Zfish    99 HYRREV----MRSKMPNPAHLAIAECEARLGQQGRSVVIITQNIDELHHRAGSKHVYEIHGSLFK 159

  Fly   158 VKCLSCEYRIDRHEFQSILASLNPAF--KDAPDMIRPD-GDVEIPLEYIENFRIPECTQ--CGGD 217
            .:|:||......|:     :.:.||.  |.|||   |: .:..||:|.     :|.|.:  |.|.
Zfish   160 TRCMSCGEVKANHK-----SPICPALDGKGAPD---PNTKEARIPVEL-----LPRCERKSCNGL 211

  Fly   218 LKPEIVFFGDSVPRPRVDQIAGMVYNSDGLLVLGSSLLVFSGYRVVLQTKDLKLPVGIVNIGETR 282
            |:|.:|:||:::....:..:...:...|..||:|:|.:|:.......|.....:||...|:..|.
Zfish   212 LRPHVVWFGETLDSDILTAVERELEKCDLCLVVGTSSIVYPAAMFAPQVASRGVPVAEFNMECTP 276

  Fly   283 ADHLADIKISAKCGDVIPKLFDFRNSKSV 311
            |...........||..:|...:...|::|
Zfish   277 ATQRFKYHFEGPCGSTLPPALERHESEAV 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	77/271 (28%)
sirt5	NP_001002605.1	SIRT5_Af1_CobB	47..297	CDD:238703	78/267 (29%)