Protein Alignment Sirt4 and Sirt6

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_649990.2
• Gene: Sirt6 / 41254
• FlyBaseID: FBgn0037802
• Length: 325
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 79/293 - (26%)
• Similarity: 125/293 - (42%)
• Gaps: 75/293 - (25%)

  Fly    30 VVEDDIKRLEDFLLSKPNVLVLTGAGISTESGIPDYRS-EGVGLYARSNHKPVQHMEFVKSSAVR 93
            ||.:..:.|.:.:....:|::.|||||||.:||||:|. :||........||    :|..|
  Fly    29 VVAEKCQELAELIKKSGHVVLHTGAGISTSAGIPDFRGPKGVWTLEEKGEKP----DFNVS---- 85

  Fly    94 KRYWARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVHGSGY 156
                         |...:|..||.|:........||.|::||:|.||.|:|  .:.:.|:||:.|
  Fly    86 -------------FDEARPTKTHMAIIALIESGYVQYVISQNIDGLHLKSGLDRKYLSELHGNIY 137

  Fly   157 VVKCLSCEYRIDRHEFQSILA-------SLNPAFKDAPDMIRPDGDVEIPLEYIENFRIPECTQC 214
            :.:|..|     |.:|.|..|       ||..|.|.:.|                        ..
  Fly   138 IEQCKKC-----RRQFVSPSAVETVGQKSLQRACKSSMD------------------------SK 173

  Fly   215 GGDLKPEIVFFGDSV-----PRPRVDQIAGMVYN--SDGLLVLGSSL-LVFSGYRVVLQTKDLKL 271
            |...:..|::  |:|     ..|..|...|::::  :|..:.||::| :|.||   .|..|:||.
  Fly   174 GRSCRSGILY--DNVLDWEHDLPENDLEMGVMHSTVADLNIALGTTLQIVPSG---DLPLKNLKC 233

  Fly   272 --PVGIVNIGETRADHLADIKISAKCGDVIPKL 302
              ...|.|:..|:.|..|::.||:....|:.|:
  Fly   234 GGKFVICNLQPTKHDKKANLIISSYVDVVLSKV 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	75/280 (27%)
Sirt6	NP_649990.2	SIRT7	45..258	CDD:238701	74/267 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438948
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48252
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840