Protein Alignment Sirt4 and Sirt6

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_001026819.1
• Gene: Sirt6 / 299638
• RGDID: 1305216
• Length: 330
• Species: Rattus norvegicus
• Alignment Length: 288
• Identity: 74/288 - (25%)
• Similarity: 120/288 - (41%)
• Gaps: 68/288 - (23%)

  Fly    31 VEDDIKRLEDFLLSKPNVLVLTGAGISTESGIPDYRS-EGVGLYARSNHKPVQHMEFVKSSAVRK 94
            :|..:..|...:.....|:..|||||||.|||||:|. .||
  Rat    30 LECKVWELARLMWQSSTVVFHTGAGISTASGIPDFRGPHGV------------------------ 70

  Fly    95 RYWARNFVGW-PKFSAT----QPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVH 152
              |.....|. |||..|    :|:.||.||.:.||...:..:|:||||.||.::|  ...:.|:|
  Rat    71 --WTMEERGLAPKFDITFENARPSKTHMALVQLERMGFLSFLVSQNVDGLHVRSGFPRDKLAELH 133

  Fly   153 GSGYVVKCLSCEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLEYIENFRIPECT----- 212
            |:.:|.:|..|:.:..|   .:::.::.         ::..|.:              ||
  Rat   134 GNMFVEECPKCKTQYVR---DTVVGTMG---------LKATGRL--------------CTVAKAR 172

  Fly   213 ---QCGGDLKPEIVFFGDSVPRPRVDQIAGMVYNSDGLLVLGSSLLVFSGYRVVLQTKDLKLPVG 274
               .|.|:|:..|:.:.|::|...:.........:|..:.||:||.:.....:.|.||.....:.
  Rat   173 GLRACRGELRDTILDWEDALPDRDLTLADEASRTADLSVTLGTSLQIRPSGNLPLATKRRGGRLV 237

  Fly   275 IVNIGETRADHLADIKISAKCGDVIPKL 302
            |||:..|:.|..||:.|.....:|:.||
  Rat   238 IVNLQPTKHDRQADLCIHGYVDEVMCKL 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	70/276 (25%)
Sirt6	NP_001026819.1	SIRT7	45..257	CDD:238701	69/263 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810