Protein Alignment Sirt4 and Sirt7

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_694696.2
• Gene: Sirt7 / 209011
• MGIID: 2385849
• Length: 402
• Species: Mus musculus
• Alignment Length: 322
• Identity: 88/322 - (27%)
• Similarity: 134/322 - (41%)
• Gaps: 85/322 - (26%)

  Fly    12 TSLRSSTARQEYVPHHKPVVEDD-------IKRLEDFLLSKPNVLVLTGAGISTESGIPDYRS-E 68
            |.|:..:.|:|.:...:..|.||       ::.|...:.|..:::|.|||||||.:.|||||. .
Mouse    60 TELQGRSRRREGLKRRQEEVCDDPEELRRKVRELAGAVRSARHLVVYTGAGISTAASIPDYRGPN 124

  Fly    69 GVGLYARSNHKPVQHMEFVKSSAVRKRYWARNFVGWPKFSATQPNATHHALARFEREERVQAVVT 133
            ||....:.. :||...:                     .|..:|..||.::.|...::.||.||:
Mouse   125 GVWTLLQKG-RPVSAAD---------------------LSEAEPTLTHMSITRLHEQKLVQHVVS 167

  Fly   134 QNVDRLHTKAG-SRNVV-EVHGSGYVVKCLSCEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDV 196
            ||.|.||.::| .|..: |:||:.|:..|.||
Mouse   168 QNCDGLHLRSGLPRTAISELHGNMYIEVCTSC--------------------------------- 199

  Fly   197 EIP-LEYIENFRIPE------------CTQCGGDLKPEIVFFGD--SVPRP-RVDQIAGMVYNSD 245
             || .||:..|.:.|            |.:||..|:..||.||:  ::.:| ..:........:|
Mouse   200 -IPNREYVRVFDVTERTALHRHLTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASKAD 263

  Fly   246 GLLVLGSSLLVFSGY-RVVLQTK--DLKLPVGIVNIGETRADHLADIKISAKCGDVIPKLFD 304
            .:|.|||||.|...| |:...||  ..:..:.|||:..|..|..|.:|:..||.||:..|.:
Mouse   264 TILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMQLLMN 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	79/282 (28%)
Sirt7	NP_694696.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		SIRT7	102..315	CDD:238701	74/268 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	355..402

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810