Protein Alignment Sirt4 and LOC1273019

DIOPT Version :10

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: XP_311957.5
• Gene: LOC1273019 / 1273019
• VectorBaseID: AGAMI1_003031
• Length: 615
• Species: Anopheles gambiae
• Alignment Length: 315
• Identity: 78/315 - (24%)
• Similarity: 124/315 - (39%)
• Gaps: 98/315 - (31%)

  Fly    48 VLVLTGAGISTESGIPDYRSEGVGLYARSNH---------KPVQHMEFVKSS-----AVRKRYWA 98
            ::.:.||||||.:||||:||...|||   |:         :.:..:|::..:     .:.|..:.
Mosquito   176 IVTMVGAGISTSAGIPDFRSPNTGLY---NNLMKYNLPYPQAIFELEYLHQNPKPFFTLAKELYP 237

  Fly    99 RNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVHGSGYVVKCL 161
            ..|         :|..:|:.:...|::..:....|||:|.|...||  ...:||.||:.|...||
Mosquito   238 GTF---------KPTPSHYFVRLLEQKGLLVRHYTQNIDTLERIAGIPEDKIVEAHGTFYTNHCL 293

  Fly   162 SCEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLEYIENFRIPECTQCGGDLKPEIVFFG 226
            .|:          |..||                 |...|.|....:|.| .|||.:||:|||||
Mosquito   294 ECK----------IAYSL-----------------EFVKEKIFADEVPTC-PCGGVIKPDIVFFG 330

  Fly   227 DSVPR-----PRVDQIAGMVYNSDGLLVLGSSLLVFSGYRVVLQTKD--LKL-----PVGIVNIG 279
            :.:|.     |..|     ....|.|:::|:||.|.....:|....|  ::|     .||..:.|
Mosquito   331 EGLPERFHMLPHQD-----FAECDLLIIMGTSLTVQPFASLVEYVNDDCVRLLINRDKVGCNSFG 390

  Fly   280 ETRA------------DHLADIKISAKC-------------GDVIPKLFDFRNSK 309
            ..|:            .:..|:..:..|             ||.:.||.:..::|
Mosquito   391 FLRSMVFGEGLCFDLPGNRRDVAWTGNCDDGCFFLADQLGWGDELRKLVETEHAK 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	75/303 (25%)
LOC1273019	XP_311957.5	SIRT1	174..422	CDD:238699	73/290 (25%)