Protein Alignment Pop1 and POP1

DIOPT Version :10

• Sequence 1: NP_572236.3
• Gene: Pop1 / 31475
• FlyBaseID: FBgn0026702
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_014178.1
• Gene: POP1 / 855500
• SGDID: S000005165
• Length: 875
• Species: Saccharomyces cerevisiae
• Alignment Length: 898
• Identity: 180/898 - (20%)
• Similarity: 290/898 - (32%)
• Gaps: 330/898 - (36%)

  Fly    13 GGRVTLPSHVTTYHYAAEALQEIRNLVADCQETTQRSSKLIFQTLPKHMRRRAMSHHPKRLPRKY 77
            |.::.:...:::..:      |::.|......:...||..|||.||:.:|||..||:.:|:|::.
Yeast    54 GSKLNVDQFISSRQF------EVKQLQLAMHNSKAASSTRIFQALPRKLRRRTASHNVRRIPKRM 112

  Fly    78 RQAHKSQMGKSGNQPV--NGKRPSRK--------------------------------------- 101
            |.....:|.||..|.|  .....|||
Yeast   113 RNRALREMRKSDQQDVLKGSSASSRKAHGLNAKQLYKARMSIKLLRLASKSTSMKLSMPPEVTSS 177

  Fly   102 ---YRRRPKNLMR--------------------------------------EYVRRQRRHVWLET 125
               .|::.|.|.|                                      :|.:||:...||.|
Yeast   178 NCHVRQKIKTLKRMIKESSTANPNIKLLNNRMGSYDCTGVNELAPIPKGRVKYTKRQKHFAWLPT 242

  Fly   126 HIWHAKRFHMVDRWGHRLPYASCDKTYRACYRASAEHC-----LLQDISFYGCVELRGPL----- 180
            |||:|||.||:.|||:::.:|...|.::..:|...:.|     |..|.|:.|.:.::...
Yeast   243 HIWNAKRSHMMKRWGYQMVWAPTQKCFKLTHRLGGDTCSSDGALCMDSSYIGTIIVKDKSNDSEG 307

  Fly   181 DMLREGFARLTSPQCGLGITARTFLSGRREGSVELFEDGRYPYGALQRASFMWRPRREEEDEKQT 245
            |.|:....:||:.:..|    |.:    |||.| ||:...|.:             .||..|..|
Yeast   308 DFLKSIIGKLTAERANL----RKY----REGQV-LFQGLIYSF-------------NEENGEDST 350

  Fly   246 N-----HTLW-------LWLHPSGAQAVLNQLISVFQLKSTRQQKLPLNEAVTEEKMDVDKIEPV 298
            .     ...|       :.||||....|.|.|:         |.|         ||:.|.... .
Yeast   351 KPLGPCDVFWVQKDTAIIRLHPSIYTQVFNILL---------QHK---------EKLTVQDCR-Y 396

  Fly   299 ELSKETSPGKKNSKKKPEQRPLRFWTKTKAFDPQPSYFNSDGTLHLVLLQREFNRFRLTGPRAQK 363
            .|:..|..|                  .||.:...|...|      ....:.|.:|::    ...
Yeast   397 SLASVTLKG------------------AKALESLASCLRS------TEYSKSFEQFKM----VSM 433

  Fly   364 VLFASLRPHREEELQDKANYCQAALQLSSPAELLSNLVMAHLVVDPR-LQRPKKRTKAVGKMEQP 427
            :...:..|.|          |..|.:                .:||| |..|||    :...::.
Yeast   434 ITDHNALPQR----------CTFAFE----------------AIDPRHLAAPKK----LNDSQRK 468

  Fly   428 PLSAGDLLM---NQPKSL----------PESPLWSKKARERLAKGIMSAHKYDQLREQHAVVPGA 479
            .:::.|:|.   |.|:..          |||...|...:..|.:  :||.:|..|......:...
Yeast   469 TVNSDDILSLHENYPQDEINAVFNELCDPESRTQSYNNQNTLKE--ISARRYKLLTATPNSINKT 531

  Fly   480 PCAF-EQQMQALPVILIQRPGSQDPRYKRLGYGCGWDVIAPAGYGMTLWLTLT----MWGARPGG 539
            ...| |....::|:::|:|..::|           |.|:.|..:.:.||..|.    |:..   |
Yeast   532 TVPFKESDDPSIPLVIIRRLKTRD-----------WIVVLPWFWLLPLWHLLNRIPRMYHI---G 582

  Fly   540 LRELDSVAREAGAEIHLPD-----TLAGVQRAAASADELRARYFRMPPNKRTNYRKLAVVSP--- 596
            ||:...:..| ..:::.||     .|..::.:....:..:.::.|.|..||.|:.|:..:..
Yeast   583 LRQFQQIQYE-NKQLYFPDDYPFTQLGYIENSFYKKEASKTKWDRKPMGKRINFEKIKDIHNTKL 646

  Fly   597 ----------FTAPWRHL--------------------------------VRD------------ 607
                      |::.||.|                                |||
Yeast   647 PAYSGEIGDFFSSDWRFLQILRNGIDYLQRNDKTLELMDSKKTGQFNAQGVRDINCVNDVLEFCK 711

  Fly   608 -----WRASFSSASEGSSFYVLRHRQQLEEIVESIR-HRSPLPQTLPDDAIIQIQLQLLSRGHVK 666
                 .:|...|..|.....:.::|:......:||. :.|....|.....||.:...||.|||.|
Yeast   712 DYEAKTKAMSLSIEENIPVALCKNRKCQFRTPDSISVNSSSFSLTFFPRCIIAVSCTLLERGHPK 776

  Fly   667 DNALICLPTAADHKKRWRQLKHNDQAPVHVEPTQPDLNEQLRKELRQSHKLKL 719
            |||.|......| .:.|.||......|                ..|:.|.||:
Yeast   777 DNARIYQVPEKD-LEHWLQLAKGVYRP----------------NGRKDHDLKI 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pop1	NP_572236.3	POP1	33..179	CDD:429227	54/232 (23%)
		POPLD	513..601	CDD:462391	21/109 (19%)
POP1	NP_014178.1	POP1	62..300	CDD:429227	54/243 (22%)
		POPLD	555..661	CDD:462391	22/120 (18%)