Protein Alignment Pop1 and Pop1

DIOPT Version :10

• Sequence 1: NP_572236.3
• Gene: Pop1 / 31475
• FlyBaseID: FBgn0026702
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_690854.1
• Gene: Pop1 / 67724
• MGIID: 1914974
• Length: 1045
• Species: Mus musculus
• Alignment Length: 1021
• Identity: 287/1021 - (28%)
• Similarity: 436/1021 - (42%)
• Gaps: 261/1021 - (25%)

  Fly    18 LPSHVTTYHYAAEALQEIRNLVADCQETTQRSS-KLIFQTLPKHMRRRAMSHHPKRLPRKYRQAH 81
            :|.::|...:|.....||..::   :..||:|| .|:|||||:|||||||||:.|||||:.::..
Mouse    98 IPKYITASTFAQARAAEISAML---KAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEMA 159

  Fly    82 KSQMGKSGNQ-PVNGKRPSRKYRRRPKNLMREYVRRQRRHVWLETHIWHAKRFHMVDRWGHRLPY 145
            |.:..|:.:| ..:.|....|.||...|...|:.|||::::|||||||||||||||.:||:.|..
Mouse   160 KKEAEKAAHQKKEHSKNKCHKARRCHINRTLEFNRRQQKNIWLETHIWHAKRFHMVKKWGYCLGE 224

  Fly   146 ASCDKTYRACYRASAEHCLLQDISFYGCVELRGPLDMLREGFARLTSPQCGLGITARTFLSGRRE 210
            ....|::||||||....|||||:|:|.|:||:|..:.|.:..:::.|...||...|...|||:|:
Mouse   225 RPTAKSHRACYRAMTNLCLLQDLSYYCCLELKGKEEELLKALSQMCSIDAGLTFAAVHCLSGKRQ 289

  Fly   211 GSVELFEDGRYPYGALQRASFMWRPRREEEDEKQTNHTLWLWLHPSGAQAVLNQLISVFQLKSTR 275
            ||:.|:...:||...|...:|:|:.|...||..: :..||:||||:...|||.      ::|:|.
Mouse   290 GSLMLYRANKYPREMLGPVTFIWKSRMTPEDASE-DRQLWIWLHPTLKLAVLE------EIKTTC 347

  Fly   276 QQKLPLNEAV-------TEEKMDV------DKIEPVELSKETSPGKKNSKK------KPEQRPLR 321
            ....|:...:       |....|:      |||......::.......:||      :...:| |
Mouse   348 HCSEPVKSNICMPDPLLTPAPEDIQAGLAGDKISKKRKRRDDGESVSRAKKTIGDGTRDACQP-R 411

  Fly   322 FWTKTKAFDPQPSYFNSDGTLHLVLLQREFNRFRLTGPRAQKVLFASLRP---HR-EEELQDKAN 382
            .|.     .|......||.|:       |.|||||.||.:..:|.::||.   |. ||:.::..:
Mouse   412 SWR-----SPTTGIIVSDLTM-------EMNRFRLIGPLSHCILTSALRAAPVHTGEEDAEETPH 464

  Fly   383 Y-----C------------QAALQL----SSPAELLSNLVMAHLVVDPRLQRPKKRTKAVGKMEQ 426
            :     |            :|..:|    |||||:.:..::...|.|||:..|.:|::|:...|:
Mouse   465 HWWTDTCRSSDGRSLHQRQEAVFELLGGISSPAEIPAGTILGLTVRDPRVNLPPQRSRALPDPER 529

  Fly   427 ----------------------PPLS------AGD-----LLMNQPKSLPESPLWSKKARERLAK 458
                                  .|||      |.:     ||...|.:...|.:|.:.....:.:
Mouse   530 YQVSEFTCEEGMCTGSWSCAHWKPLSDHTDDPANERVKQLLLEGVPVACAHSFIWDQDICRSVTE 594

  Fly   459 GIMSAHKYDQLREQHAVVPGAPCAFEQQMQALPVILIQRPG---SQDPRYKRLGYGCGWDVIAPA 520
            ..:.....:::|.: .:|||:......:...:|::|||:||   .:|    |||:|.||||:.|.
Mouse   595 NKLLDQDLNRMRSE-LLVPGSQLDLGARESKIPILLIQQPGKVTGED----RLGWGSGWDVLIPK 654

  Fly   521 GYGMTLWLTLTMWGARPGGLRELDSVAREAGAEIH------------LPDTLAGVQRAAASADEL 573
            |:||..|:.....|||.|||:|         |.:|            .||..|||..|...|.:|
Mouse   655 GWGMAFWIPFIYRGARVGGLKE---------ATVHSQYRRSPNIPGDFPDCRAGVLFAEDQAKDL 710

  Fly   574 RARYFRMPPNKRTNYRKLAVVSPFTAPWRHLVRDWR-----------ASFSSASE---------- 617
            ..:|.|.||.||.||.||..::||..||..|.|||.           ||...|.|
Mouse   711 LEKYRRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRVHAQEAAIIASMPGAQETDPRRLGVPC 775

  Fly   618 -------------------------------------------------GSSFYVLRHRQQLEEI 633
                                                             ||...|:|.|:.|:::
Mouse   776 VPKEICQLSNEAGIAENQPRKPEVTGCQAQEGTKVAMEWNASEAHMATTGSQLCVVRSRKLLKQL 840

  Fly   634 ------VESIRHRSP--LPQTLPDD-----------AIIQIQLQLLSRGHVKDNALICLPTAAD- 678
                  ...|| |:|  ..|.|..:           |::.:.|.||.:|..:.:.:||:|:..|
Mouse   841 SSWCGPSSEIR-RAPCRAQQELTSNVCLSILNDFPRALVWVSLSLLRKGSPEPHTMICVPSKEDL 904

  Fly   679 HKKRWRQLKHNDQAPVHVEPTQPDLNEQLRKELRQSHKLKLKRLRSRRVREKRRLQETATKRVHI 743
            |:....|..|......|.:|    ....:.||       |.|:.:.:|...:.|..|.......|
Mouse   905 HRLSQDQCYHGPWESRHSDP----FKSLILKE-------KEKKKKEKRQDGEHRASEGQAAGPPI 958

  Fly   744 RPANTAHLVRGQLQEMCRLW---LPTDPAELRDSVRRQCSRQVFGYVSTAGFSFTEALVCAVGYV 805
              |....|.:|       ||   ||        .:...|||.:.|:|:...||.......|:|:|
Mouse   959 --AGQEALTQG-------LWSGPLP--------GLTSHCSRLLLGFVTQGDFSMAAGCGEALGFV 1006

  Fly   806 TPAG-LQQLIEELPASKGNRKQPPLMCLVRDADSRDYRWASFQVNL 850
            :..| |:.|..:..|.:|       :.|:|...|..||:|...:.:
Mouse  1007 SMTGLLEMLSSQSAAMRG-------LVLLRPPTSLQYRFARITIEV 1045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pop1	NP_572236.3	POP1	33..179	CDD:429227	73/147 (50%)
		POPLD	513..601	CDD:462391	38/99 (38%)
Pop1	NP_690854.1	POP1	107..257	CDD:429227	73/151 (48%)
		POPLD	647..738	CDD:462391	37/179 (21%)