Protein Alignment Pop1 and Pop1

DIOPT Version :10

• Sequence 1: NP_572236.3
• Gene: Pop1 / 31475
• FlyBaseID: FBgn0026702
• Length: 857
• Species: Drosophila melanogaster
• Sequence 2: NP_001124022.1
• Gene: Pop1 / 315045
• RGDID: 1308609
• Length: 1044
• Species: Rattus norvegicus
• Alignment Length: 1022
• Identity: 291/1022 - (28%)
• Similarity: 443/1022 - (43%)
• Gaps: 263/1022 - (25%)

  Fly    18 LPSHVTTYHYAAEALQEIRNLVADCQETTQRSS-KLIFQTLPKHMRRRAMSHHPKRLPRKYRQAH 81
            :|.::|...:|.....||..::   :..||:|| .|:|||||:|||||||||:.|||||:.::..
  Rat    97 IPKYITASTFAQARAAEISAML---KAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEMA 158

  Fly    82 KSQMGKSGNQ-PVNGKRPSRKYRRRPKNLMREYVRRQRRHVWLETHIWHAKRFHMVDRWGHRLPY 145
            |.:..|:.:| ..:.|....|.||...|...|:.|||::::|||||||||||||||.|||:.|..
  Rat   159 KKEAEKAAHQKKEHSKNKCHKARRCHINRTLEFNRRQQKNIWLETHIWHAKRFHMVKRWGYCLGE 223

  Fly   146 ASCDKTYRACYRASAEHCLLQDISFYGCVELRGPLDMLREGFARLTSPQCGLGITARTFLSGRRE 210
            ....|::||||||..:.|||||:|:|.|:||:|..:.:.:..:::.|...||...|...|||:|:
  Rat   224 RPTAKSHRACYRAMTDLCLLQDLSYYCCLELKGKEEEILKALSQMCSIDTGLTFAAVHCLSGKRQ 288

  Fly   211 GSVELFEDGRYPYGALQRASFMWRPRR---EEEDEKQTNHTLWLWLHPSGAQAVLNQLISVFQLK 272
            ||:.|:...:||...|...:|:|:.|.   :..:|:|    ||:||||:...|||.      ::|
  Rat   289 GSLMLYRANKYPRDMLGPVTFIWKSRETPGDASEERQ----LWIWLHPTLKLAVLE------EIK 343

  Fly   273 STRQQKLPLNEAV-------TEEKMDV------DKIEPVELSKETSPGKKNSKKKPEQRPLRFWT 324
            :|.|...|:..:|       |..:.|:      |||           |||. |::.:....|...
  Rat   344 TTCQCSEPVKPSVCVPAPLLTPAQEDIQAGLADDKI-----------GKKR-KRRDDGENARRAK 396

  Fly   325 KT---KAFDP-QPSYFNSDGTLHLVL-LQREFNRFRLTGPRAQKVLFASLRP---HREEELQDKA 381
            ||   ...|| ||..:.|..|..:|. |..|.|||||.||.:..:|.::||.   ||.||..::.
  Rat   397 KTIGDGTGDPCQPRSWLSPTTGIVVSDLTMEMNRFRLVGPLSHCILTSALRAAPVHRGEEDAEET 461

  Fly   382 NY------C------------QAALQL----SSPAELLSNLVMAHLVVDPRLQRPKKRTKAVGKM 424
            .:      |            :|..||    |||||:.:..::...|.|||:..|.:|.:|:...
  Rat   462 PHGWWTDTCRSPHGLSLHQRQEAVFQLLGGISSPAEIPAGTILGLTVRDPRVNLPPQRCRALPDP 526

  Fly   425 EQ----------------------PPLS--AGD---------LLMNQPKSLPESPLWSKKARERL 456
            |:                      .|||  ..|         ||...|.....|.:|::...:.:
  Rat   527 ERYHVSEFICEEGMCTSSWSCAHWKPLSDHTDDPDNEQVKQLLLEGVPVECAHSFIWNQDICQSV 591

  Fly   457 AKGIMSAHKYDQLREQHAVVPGAPCAFEQQMQALPVILIQRPG---SQDPRYKRLGYGCGWDVIA 518
            .:..:.....:::|.: .:|||:......:...:|::|||:||   .:|    |||:|.|||::.
  Rat   592 TENKIVDQDLNRMRSE-LLVPGSQLVLGARESKIPILLIQQPGKVTGED----RLGWGSGWDILL 651

  Fly   519 PAGYGMTLWLTLTMWGARPGGLRELDSVAREAGAEIH------------LPDTLAGVQRAAASAD 571
            |.|:||..|:.....|||.|||:|         |.:|            .||..|||..|...|.
  Rat   652 PKGWGMAFWIPFIYRGARVGGLKE---------AAVHSQYKRSPNVPGDFPDCRAGVLFAEDQAK 707

  Fly   572 ELRARYFRMPPNKRTNYRKLAVVSPFTAPWRHLVRDWRASFS----------------------- 613
            :|..:|.|.||.||.||.||..::||..||..|.|||.:...
  Rat   708 DLLEKYQRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRIQTQEAAVIDSVPGAQETDPRRLGV 772

  Fly   614 -----------------------------------------------SASEGSSFYVLRHRQQLE 631
                                                           :|:.||...|:|.|:.|:
  Rat   773 PCVPKETCQLSNEASIAENQPRKPEVTGCQAQAGTEVALEQNASEDHAAATGSQLCVVRSRKLLK 837

  Fly   632 EI------VESIRH----------RSPLPQTLPD--DAIIQIQLQLLSRGHVKDNALICLPTAAD 678
            ::      ...:|.          |......|.|  .|::.:.|.||.:|..:.:.:||:|:..|
  Rat   838 QLSSWCGPSSEVRRAPCRGQQELTRKACLSILADFPRALVWVSLSLLKKGSPEPHTMICVPSKED 902

  Fly   679 -HKKRWRQLKHNDQAPVHVEPTQPDLNEQLRKELRQSHKLKLKRLRSRRVREKRRLQETATKRVH 742
             .:....|..|......|.:|.:               .|.||. :.::.:|||:..|....:..
  Rat   903 LFQLSQDQCYHGPCESRHSDPFK---------------SLILKE-KEKKKKEKRQDGEQGASKGQ 951

  Fly   743 IRPANTAHLVRGQLQEMCRLW---LPTDPAELRDSVRRQCSRQVFGYVSTAGFSFTEALVCAVGY 804
            ...|.||    ||...:..||   ||        .:...|||.:.|:|:...||.......|:|:
  Rat   952 AAGAPTA----GQEARIQGLWSGPLP--------GLTSHCSRPLLGFVTHGDFSMAVGCGEALGF 1004

  Fly   805 VTPAG-LQQLIEELPASKGNRKQPPLMCLVRDADSRDYRWASFQVNL 850
            |:..| |:.|..:..|.:|       :.|:|...|..||:|...:.:
  Rat  1005 VSVTGLLEMLSSQSAAMRG-------LVLLRPPTSLQYRFARVTIEV 1044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pop1	NP_572236.3	POP1	33..179	CDD:429227	74/147 (50%)
		POPLD	513..601	CDD:462391	37/99 (37%)
Pop1	NP_001124022.1	POP1	106..256	CDD:429227	74/151 (49%)
		POPLD	646..737	CDD:462391	32/178 (18%)