DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlc-c and mlc-3

DIOPT Version :9

Sequence 1:	NP_001245533.1	Gene:	Mlc-c / 31474	FlyBaseID:	FBgn0004687	Length:	153	Species:	Drosophila melanogaster
Sequence 2:	NP_741145.1	Gene:	mlc-3 / 175768	WormBaseID:	WBGene00003371	Length:	153	Species:	Caenorhabditis elegans

Alignment Length:	138	Identity:	60/138 - (43%)
Similarity:	94/138 - (68%)	Gaps:	3/138 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 QEAFNLFDNRGDGKIQLSQVGECLRALGQNPTESDVKKCTHQ---LKPDERISFEVFLPIYQAIS 80
            :|.|||:|...||||..:|||:..||.|..||::.|.|...|   .|.::|::||.:||:|:.::
Worm    10 KEIFNLYDEELDGKIDGTQVGDVARAAGLKPTQAMVTKAAGQEFKRKGEKRLTFEEWLPMYEQLA 74

  Fly    81 KARSGDTADDFIEGLRHFDKDASGYISSAELRHLLTTLGEKLTDEEVEQLLANMEDQQGNINYEE 145
            |.:...|..||.|||:.|||:.:|.|.:|||||:|..|||:|:.:|.::||..:||.:|.:.||:
Worm    75 KEKEQGTYADFYEGLKVFDKEETGKILAAELRHILLALGERLSADEADELLKGVEDGEGMVKYED 139

  Fly   146 FVRMVMSG 153
            |::.|::|
Worm   140 FIKKVLAG 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlc-c	NP_001245533.1	PTZ00184	14..152	CDD:185504	59/135 (44%)
mlc-3	NP_741145.1	EF-hand_7	9..70	CDD:290234	26/59 (44%)
mlc-3	NP_741145.1	EFh	90..142	CDD:298682	24/51 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	1	1.000	-	-		FOG0000359
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920