Protein Alignment RhoGAP5A and BEM3

DIOPT Version :10

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_015210.1
• Gene: BEM3 / 855988
• SGDID: S000006036
• Length: 1128
• Species: Saccharomyces cerevisiae
• Alignment Length: 216
• Identity: 67/216 - (31%)
• Similarity: 103/216 - (47%)
• Gaps: 37/216 - (17%)

  Fly   301 VFGTDLTTMVQLEPH-----HQIPFVVRRCVEEV-EARGMLQEGIYRVSGFADEIEALKLALDR- 358
            :||:.|.|.::|..|     :.:|.||.||:|.: :.||:.:|||:|:||.:..|:.|:...|:
Yeast   904 IFGSSLETCLRLSSHKYQNVYDLPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTVIKTLQERFDKE 968

  Fly   359 ------------EGEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSF-MAAGRTGKQA 410
                        |.:..:.|.:.|..||.::|.||||||.||..|...:.:.|| ..........
Yeast   969 YDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKLPHLLFGDEQFLSFKRVVDENHNNP 1033

  Fly   411 EQ-----RQLMAEAVRRLPPAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQHM 470
            .|     ::|:...:  :|.|:.|.:..:.|.|.|:..:...||||..||..||:|||
Yeast  1034 VQISLGFKELIESGL--VPHANLSLMYALFELLVRINENSKFNKMNLRNLCIVFSPTL------- 1089

  Fly   471 TNLTEEIFMLSSLITHCKTIF 491
             |:  .|.||...||....||
Yeast  1090 -NI--PISMLQPFITDFACIF 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215
		C1_CHN	241..293	CDD:410356
		RhoGAP_chimaerin	302..491	CDD:239837	65/213 (31%)
BEM3	NP_015210.1	PX	520..622	CDD:214610
		PH_Bem3	633..741	CDD:270096
		RhoGAP	904..1110	CDD:470621	67/216 (31%)