Protein Alignment RhoGAP5A and Chn1

DIOPT Version :9

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_038961900.1
• Gene: Chn1 / 84030
• RGDID: 620139
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 192/499 - (38%)
• Similarity: 274/499 - (54%)
• Gaps: 80/499 - (16%)

  Fly     2 PRNTEAGAGNANTGGSGG------VGGAPEPSSPVQKVWKPELYKLQLEAPAPCPLRCQRTLPLP 60
            ||.....|..|.:.|..|      :....|...|   |||..||:||.|||.|..:.|
  Rat   102 PRCRLPAAAGARSAGRRGSTMALTLFDTDEYRPP---VWKSYLYQLQQEAPHPRRVTC------- 156

  Fly    61 PAKSTAEAVEANNLAGRLYGSEYHGLMGHLEAEQLLANARDGSYFVRRSPQSDGYYTLSLRFNKR 125
                   ..|..| ..:.||.|:||::...|.:|||:.| :|||.:|.|.:..|.|||:|||..:
  Rat   157 -------TCEVEN-RPKYYGREFHGMISREETDQLLSVA-EGSYLIRESQRQPGTYTLALRFGSQ 212

  Fly   126 PKHYKLLYKPGVGHYLRGQDKRFDTVHDMVADGLINFHMQLHASPIIQQINQQTKN-CYQQSPYM 189
            .::::|.|.   |.:..| :|||:::||:|.||||..:::..|:   :.|.:.|.| .|:...|.
  Rat   213 TRNFRLYYD---GKHFVG-EKRFESIHDLVTDGLITLYIETKAA---EYIAKMTINPIYEHIGYT 270

  Fly   190 TLN-------------------------GRKLRALSNELGKAAAKESKESPAEEKEQKQEEPPPP 229
            |||                         |...:.|::.:.:|..||:::.|.
  Rat   271 TLNREPAYKQHMAVLKETHDEKEATGQDGVSEKRLTSLVRRATLKENEQIPK------------- 322

  Fly   230 AVDPMPLVYEKPHHFKVHTFKGLNWCEFCANFLWGFTAQGVKCEACGFVAHSKCSELVPPKCVPD 294
                    |||.|:||||||:|.:|||:||||:||..||||||..||...|.:||::||..|.||
  Rat   323 --------YEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPD 379

  Fly   295 LKRIRGVFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDRE 359
            ||.::.|:..||||:|:.....: |.||..|:.|:|:||:..||:||||||:|.||.:|:|.||:
  Rat   380 LKHVKKVYSCDLTTLVKAHITKR-PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRD 443

  Fly   360 GEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQRQLMAEAVRRLP 424
            |||.|:|...|.::|:|.|.||||.|.||:||||:.|||.|:.:.:.....||.:.:.||:|.||
  Rat   444 GEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIVDPDEQLETLHEALRSLP 508

  Fly   425 PAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQ 468
            |||...|:|::.|||||..|...|.|:..||..||.|||:.:|:
  Rat   509 PAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPE 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215	36/90 (40%)
		C1_1	242..294	CDD:278556	31/51 (61%)
		RhoGAP_chimaerin	302..491	CDD:239837	80/167 (48%)
Chn1	XP_038961900.1	SH2_a2chimerin_b2chimerin	163..249	CDD:198215	36/90 (40%)
		C1_alphaCHN	322..378	CDD:410406	34/76 (45%)
		RhoGAP_chimaerin	387..580	CDD:239837	80/167 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337260
Domainoid	1	1.000	160	1.000	Domainoid score	I3966
eggNOG	1	0.900	-	-		E1_KOG1453
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49440
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	1	1.000	-	-		FOG0001164
OrthoInspector	1	1.000	-	-		otm45875
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46075
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2268
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.820