DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP5A and AT4G03100

DIOPT Version :9

Sequence 1:	NP_727007.1	Gene:	RhoGAP5A / 31473	FlyBaseID:	FBgn0029778	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_192219.2	Gene:	AT4G03100 / 828092	AraportID:	AT4G03100	Length:	430	Species:	Arabidopsis thaliana

Alignment Length:	351	Identity:	71/351 - (20%)
Similarity:	118/351 - (33%)	Gaps:	129/351 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 GKAAAKESKESPAEEKEQKQEEPPPPAVDPMPLV-----------------------------YE 239
            ||...::|.....||:||.|::        :.||                             ..
plant    17 GKGGRRKSTAEEEEEEEQNQQQ--------LSLVEFLLTALRKSVVSCRVDNRQDDGGVGGGISS 73

  Fly   240 KPHHFKV-----------------HTFKGLNWCEFCANFLWGFTAQGVKCEACGFVAHSKCSEL- 286
            ..||.::                 |.|.||                          .|....|:
plant    74 AVHHMEIGWPTNVRHITHVTFDRFHGFLGL--------------------------PHELQVEIP 112

  Fly   287 --VPPKCVPDLKRIRGVFGTDLTTMVQL---EPHHQIPFVVRRCVEEV-EARGMLQEGIYRVSGF 345
              ||...|       .|||....:| |.   |..:.:|.::....|.: ..:|:..|||:|::..
plant   113 CRVPSASV-------SVFGVSAESM-QCSYDEKGNSVPTILLLMQERLYSQQGLKAEGIFRINPE 169

  Fly   346 ADEIEALKLALDR--EGEKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGK 408
            ..:.|.::..|:|  ..|..|        |:.:||.:|.:.|.||..::             .|.
plant   170 NSQEEHVRDQLNRGIVPENID--------VHCLAGLIKAWFRELPSGVL-------------DGL 213

  Fly   409 QAEQ------RQLMAEAVRRLPPAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATP 467
            ..|:      .....|.:::|.|...:.|.:.::.:..|......||||..|:|.||||.:....
plant   214 SPEEVLNCNTEDESVELIKQLKPTESALLNWAVDLMADVVEEEESNKMNARNIAMVFAPNMTQMT 278

  Fly   468 QHMTNL---TEEIFMLSSLITHCKTI 490
            ..:|.|   .:.:.:|.:|||  ||:
plant   279 DPLTALMHAVQVMNLLKTLIT--KTL 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215
		C1_1	242..294	CDD:278556	11/71 (15%)
		RhoGAP_chimaerin	302..491	CDD:239837	49/204 (24%)
AT4G03100	NP_192219.2	PBD	80..113	CDD:197628	6/58 (10%)
AT4G03100	NP_192219.2	RhoGAP	140..298	CDD:214618	39/178 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910