Protein Alignment RhoGAP5A and arhgap32a

DIOPT Version :9

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_690921.4
• Gene: arhgap32a / 562449
• ZFINID: ZDB-GENE-060503-918
• Length: 1676
• Species: Danio rerio
• Alignment Length: 472
• Identity: 112/472 - (23%)
• Similarity: 181/472 - (38%)
• Gaps: 132/472 - (27%)

  Fly    94 QLLANARDGSYFVRRSPQSDGYYTLSLRFNKRPKHYKL-LYKPGVGHYLRGQDKRF--------- 148
            |:....|  .:.||||.:         .|....||..| :|           |:||
Zfish   144 QICCQGR--KWTVRRSYE---------EFRVLDKHLHLCIY-----------DRRFSQLPELPRI 186

  Fly   149 DTVHDMVADGLINFHMQLHASPIIQQINQQTKNCYQQSPYMTLNGRKLRALSNELGK------AA 207
            |::.|..  |.::..:..:.|. :..|.....||.....:|.::.:....|.|:...      ||
Zfish   187 DSLKDKT--GTLSQMLTAYISR-LSAIADNKINCGPALTWMEIDNKGNHLLVNDESSINVPAVAA 248

  Fly   208 AKESKESPAEEKEQKQEEPPPPAVDPMPLVYEKPHHFKVHTFKGLNWCEFCANFLWGFTAQGVKC 272
            |...|...|:..::...|     |..:..|.:.|.......::|.:          ||..
Zfish   249 AHVIKRYIAQAADELSFE-----VGDIVSVIDMPPKEDTGWWRGKH----------GFQV----- 293

  Fly   273 EACGFVAHSKCSELVPPKCVPD---------------------------------LKRIRG---- 300
               ||.. |:|.||:..| :|.                                 ||: ||
Zfish   294 ---GFFP-SECVELISEK-IPSNVTSSLAKPVSKKHGKLITFLRTFMKSRPTKQKLKQ-RGILKE 352

  Fly   301 -VFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTD 364
             |||.||...: |...|.:|.|:|.|.|.:|..|:: :||||:||.:..|:.|:...|.|.....
Zfish   353 RVFGCDLGEHL-LNSGHDVPQVIRSCTEFIERHGVV-DGIYRLSGISSNIQKLRHEFDSEHVPDL 415

  Fly   365 MSETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQRQLMAEAVRRLPPAHHS 429
            ..:|...:::.:....|||.|.||.||:|:|.|..|..|.......|:...:.:.:::|||.|:.
Zfish   416 TKDTYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDDERLVKVHDVIQQLPPPHYR 480

  Fly   430 CLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQ-----------------------HMT 471
            .|::::.||.|:.::..|..|:..|||.|:||.|:.:.|                       .:.
Zfish   481 TLEFLMRHLSRMGTYSNVTNMHCKNLAIVWAPNLLRSKQIESACFSGTSAFMEVRVQSVVVEFIL 545

  Fly   472 NLTEEIF--MLSSLITH 486
            |..:.:|  .||:||.|
Zfish   546 NHVDVLFSPKLSTLIRH 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215	17/81 (21%)
		C1_1	242..294	CDD:278556	10/51 (20%)
		RhoGAP_chimaerin	302..491	CDD:239837	63/210 (30%)
arhgap32a	XP_690921.4	PX_domain	112..226	CDD:295365	22/106 (21%)
		SH3_ARHGAP32_33	248..301	CDD:212769	14/76 (18%)
		RhoGAP_CdGAP	353..547	CDD:239849	57/195 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1300981at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920