Protein Alignment RhoGAP5A and myo9b

DIOPT Version :10

• Sequence 1: NP_727007.1
• Gene: RhoGAP5A / 31473
• FlyBaseID: FBgn0029778
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_005171391.2
• Gene: myo9b / 560956
• ZFINID: ZDB-GENE-030131-938
• Length: 1974
• Species: Danio rerio
• Alignment Length: 385
• Identity: 91/385 - (23%)
• Similarity: 164/385 - (42%)
• Gaps: 61/385 - (15%)

  Fly   115 YYTLSLRFNKRPKHYKLLYKPGVGH--YLRGQDKRFDTVHDMVADGLINFHMQLHAS--PIIQQI 175
            ::|.:.:|.:..|....:..|.:|:  .:.|..|:.|::..           :..||  |::..:
Zfish  1433 FFTATTQFRETIKSMYSISNPSIGYKVLMSGYQKKVDSLAG-----------KKKASEVPLVVNL 1486

  Fly   176 NQQTKNCYQQSPYMTLNGRKLRALSNELGKAAAKESKESPAEEKEQKQEEPPPPAVDPMPLVYEK 240
            .|.           .|:|    .:..||.:..|:..|......::.|:|..|     ..||
Zfish  1487 FQS-----------VLDG----FIRGELKRIDAEPCKVKERNRRKSKREAHP-----DSPL---- 1527

  Fly   241 PHHFKVHTFKGLNWCEFCANFLWGFTAQGVKCEACGFVAHSKCSELVPPKCVPD-LKRIRGV--- 301
            .|.|..:....:..|:.|.:::||. .:...|.:|..|.|.||...:...|... :::..|.
Zfish  1528 GHLFSTYQVTIMQSCDQCTSYIWGM-EKAFMCSSCKMVCHKKCLSKITINCTAHYIRKKEGEHTL 1591

  Fly   302 -FGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTDM 365
             ||..|..:|...  ..:|||:.:.:..||..|:..|||||.||.|...:.|...|:::.....:
Zfish  1592 HFGVPLCALVHAA--DSVPFVLEQMLVHVEMNGLYTEGIYRKSGAACRAKELHQKLEKDPHTVSL 1654

  Fly   366 SETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQRQLMAEAVRRLPPAHHSC 430
            ....   ::.:.|.:|.:||.||.||:|:..|..|:.|....:.:|:.:.:...:..||.::.|.
Zfish  1655 DTYP---IHTVTGLVKQWLRELPDPLMTYSLYNDFLYAVDLPETSERLRAVYRKLEELPSSNIST 1716

  Fly   431 LQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQ-----------HMTNLTEEIFM 479
            |:.::.||.:||.....|:|:..:||.||||.::..|.           :.|.|..||.:
Zfish  1717 LERLIFHLVKVAKEEEHNRMSADSLAIVFAPCILRCPDSSDPLLSMKDINKTTLCVEILI 1776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP5A	NP_727007.1	SH2_a2chimerin_b2chimerin	75..166	CDD:198215	8/52 (15%)
		C1_CHN	241..293	CDD:410356	13/51 (25%)
		RhoGAP_chimaerin	302..491	CDD:239837	54/189 (29%)
myo9b	XP_005171391.2	None